Keratinocytes Derived from Patient-Specific Induced Pluripotent Stem Cells Recapitulate the Genetic Signature of Psoriasis Disease

Keratinocytes Derived from Patient-Specific Induced Pluripotent Stem Cells Recapitulate the Genetic Signature of Psoriasis Disease

<p dir="ltr">Psoriasis is characterized by hyperproliferation and defective differentiation of keratinocytes (KCs). Patients with psoriasis are at a high risk of developing diabetes and cardiovascular diseases. The debate on the genetic origin of psoriasis pathogenesis remains unreso...

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Bibliographic Details
Main Author: Gowher Ali (14152593) (author)
Other Authors: Ahmed K. Elsayed (13275302) (author), Manjula Nandakumar (1545811) (author), Mohammed Bashir (5593550) (author), Ihab Younis (57824) (author), Yasmin Abu Aqel (18940657) (author), Bushra Memon (4792767) (author), Ramzi Temanni (671528) (author), Fadhil Abubaker (14778163) (author), Shahrad Taheri (57360) (author), Essam M. Abdelalim (5768072) (author)
Published: 2020
Subjects:
Biological sciences
Genetics
Biomedical and clinical sciences
Clinical sciences
Medical biochemistry and metabolomics
Psoriasis
Keratinocytes (KCs)
Genetic Signature
Insulin Resistance
Diabetes and Cardiovascular Diseases
Pathogenesis
RNA Sequencing
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