Application of CRISPR/Cas gene editing for infectious disease control in poultry

<p dir="ltr">The poultry industry faces multifaceted challenges, including escalating demand for poultry products, climate change impacting feed availability, emergence of novel avian pathogens, and antimicrobial resistance. Traditional disease control measures are costly and not alw...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي: Mahdi Gallala (22457734) (author)
منشور في: 2025
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author Mahdi Gallala (22457734)
author_facet Mahdi Gallala (22457734)
author_role author
dc.creator.none.fl_str_mv Mahdi Gallala (22457734)
dc.date.none.fl_str_mv 2025-05-20T09:00:00Z
dc.identifier.none.fl_str_mv 10.1515/biol-2025-1095
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Application_of_CRISPR_Cas_gene_editing_for_infectious_disease_control_in_poultry/30393259
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Agricultural, veterinary and food sciences
Animal production
Biological sciences
Genetics
gene editing
CRISPR/Cas
poultry
infectious disease prevention and control
vaccines
disease-resilience
dc.title.none.fl_str_mv Application of CRISPR/Cas gene editing for infectious disease control in poultry
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr">The poultry industry faces multifaceted challenges, including escalating demand for poultry products, climate change impacting feed availability, emergence of novel avian pathogens, and antimicrobial resistance. Traditional disease control measures are costly and not always effective, prompting the need for complementary methods. Gene editing (GE, also called genome editing) technologies, particularly CRISPR/Cas9, offer promising solutions. This article summarizes recent advancements in utilizing CRISPR/Cas GE to enhance infectious disease control in poultry. It begins with an overview of modern GE techniques, highlighting CRISPR/Cas9’s advantages over other methods. The potential applications of CRISPR/Cas in poultry infectious disease prevention and control are explored, including the engineering of innovative vaccines, the generation of disease-resilient birds, and in vivo pathogen targeting. Additionally, insights are provided regarding regulatory frameworks and future perspectives in this rapidly evolving field.</p><h2>Other Information</h2><p dir="ltr">Published in: Open Life Sciences<br>License: <a href="http://creativecommons.org/licenses/by/4.0" target="_blank">http://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1515/biol-2025-1095" target="_blank">https://dx.doi.org/10.1515/biol-2025-1095</a></p>
eu_rights_str_mv openAccess
id Manara2_b7f598dac8b571b044a4b6dcdeccdaf9
identifier_str_mv 10.1515/biol-2025-1095
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/30393259
publishDate 2025
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spelling Application of CRISPR/Cas gene editing for infectious disease control in poultryMahdi Gallala (22457734)Agricultural, veterinary and food sciencesAnimal productionBiological sciencesGeneticsgene editingCRISPR/Caspoultryinfectious disease prevention and controlvaccinesdisease-resilience<p dir="ltr">The poultry industry faces multifaceted challenges, including escalating demand for poultry products, climate change impacting feed availability, emergence of novel avian pathogens, and antimicrobial resistance. Traditional disease control measures are costly and not always effective, prompting the need for complementary methods. Gene editing (GE, also called genome editing) technologies, particularly CRISPR/Cas9, offer promising solutions. This article summarizes recent advancements in utilizing CRISPR/Cas GE to enhance infectious disease control in poultry. It begins with an overview of modern GE techniques, highlighting CRISPR/Cas9’s advantages over other methods. The potential applications of CRISPR/Cas in poultry infectious disease prevention and control are explored, including the engineering of innovative vaccines, the generation of disease-resilient birds, and in vivo pathogen targeting. Additionally, insights are provided regarding regulatory frameworks and future perspectives in this rapidly evolving field.</p><h2>Other Information</h2><p dir="ltr">Published in: Open Life Sciences<br>License: <a href="http://creativecommons.org/licenses/by/4.0" target="_blank">http://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1515/biol-2025-1095" target="_blank">https://dx.doi.org/10.1515/biol-2025-1095</a></p>2025-05-20T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1515/biol-2025-1095https://figshare.com/articles/journal_contribution/Application_of_CRISPR_Cas_gene_editing_for_infectious_disease_control_in_poultry/30393259CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/303932592025-05-20T09:00:00Z
spellingShingle Application of CRISPR/Cas gene editing for infectious disease control in poultry
Mahdi Gallala (22457734)
Agricultural, veterinary and food sciences
Animal production
Biological sciences
Genetics
gene editing
CRISPR/Cas
poultry
infectious disease prevention and control
vaccines
disease-resilience
status_str publishedVersion
title Application of CRISPR/Cas gene editing for infectious disease control in poultry
title_full Application of CRISPR/Cas gene editing for infectious disease control in poultry
title_fullStr Application of CRISPR/Cas gene editing for infectious disease control in poultry
title_full_unstemmed Application of CRISPR/Cas gene editing for infectious disease control in poultry
title_short Application of CRISPR/Cas gene editing for infectious disease control in poultry
title_sort Application of CRISPR/Cas gene editing for infectious disease control in poultry
topic Agricultural, veterinary and food sciences
Animal production
Biological sciences
Genetics
gene editing
CRISPR/Cas
poultry
infectious disease prevention and control
vaccines
disease-resilience