Intensivist performed compression ultrasound (IPCUS) for screening and early detection of deep venous thrombosis in trauma intensive care unit: a prospective study

<h3>Introduction</h3><p dir="ltr">Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a critical complication in trauma patients, contributing to considerable morbidity and mortality. Multiple factors in trauma pose a challen...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Ahmad Kloub (16855149) (author)
مؤلفون آخرون: Nuri Abdurraheim (22502795) (author), Ahmed Ramzee (22827422) (author), Naushad Ahmad Khan (6406973) (author), Mushreq Alani (22827425) (author), Suhail Hakim (9184946) (author), Zeenat Bakhsh (17883045) (author), Ibrahim Taha (14150361) (author), Basil Younis (14150349) (author), Gustav Strandvik (9756205) (author), Tariq Siddiqui (444882) (author), Yousif Ibrahim (22827428) (author), Mohamed Nasr (9637052) (author), Sherwan Khoschnau (16855143) (author), Khalid Ahmed (710040) (author), Ahad Kanbar (9184943) (author), Ashok Parchani (768895) (author), Amor Kilani (22827431) (author), Ala’ Suliman (22827434) (author), Motasem Awwad (22827437) (author), Sana’a Odeh (22827440) (author), Lady Faye Estalilla (22827443) (author), Ana Giurgea (22827446) (author), Abdul Nasar Avayil (22827449) (author), Jenalyn Salvador (22827452) (author), Jennely Dayandante (22827455) (author), Greesha Alias (22827458) (author), Sandro Rizoli (67238) (author), Ayman El-Menyar (440103) (author), Hassan Al-Thani (440106) (author)
منشور في: 2025
الموضوعات:
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_version_ 1864513531953545216
author Ahmad Kloub (16855149)
author2 Nuri Abdurraheim (22502795)
Ahmed Ramzee (22827422)
Naushad Ahmad Khan (6406973)
Mushreq Alani (22827425)
Suhail Hakim (9184946)
Zeenat Bakhsh (17883045)
Ibrahim Taha (14150361)
Basil Younis (14150349)
Gustav Strandvik (9756205)
Tariq Siddiqui (444882)
Yousif Ibrahim (22827428)
Mohamed Nasr (9637052)
Sherwan Khoschnau (16855143)
Khalid Ahmed (710040)
Ahad Kanbar (9184943)
Ashok Parchani (768895)
Amor Kilani (22827431)
Ala’ Suliman (22827434)
Motasem Awwad (22827437)
Sana’a Odeh (22827440)
Lady Faye Estalilla (22827443)
Ana Giurgea (22827446)
Abdul Nasar Avayil (22827449)
Jenalyn Salvador (22827452)
Jennely Dayandante (22827455)
Greesha Alias (22827458)
Sandro Rizoli (67238)
Ayman El-Menyar (440103)
Hassan Al-Thani (440106)
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author_facet Ahmad Kloub (16855149)
Nuri Abdurraheim (22502795)
Ahmed Ramzee (22827422)
Naushad Ahmad Khan (6406973)
Mushreq Alani (22827425)
Suhail Hakim (9184946)
Zeenat Bakhsh (17883045)
Ibrahim Taha (14150361)
Basil Younis (14150349)
Gustav Strandvik (9756205)
Tariq Siddiqui (444882)
Yousif Ibrahim (22827428)
Mohamed Nasr (9637052)
Sherwan Khoschnau (16855143)
Khalid Ahmed (710040)
Ahad Kanbar (9184943)
Ashok Parchani (768895)
Amor Kilani (22827431)
Ala’ Suliman (22827434)
Motasem Awwad (22827437)
Sana’a Odeh (22827440)
Lady Faye Estalilla (22827443)
Ana Giurgea (22827446)
Abdul Nasar Avayil (22827449)
Jenalyn Salvador (22827452)
Jennely Dayandante (22827455)
Greesha Alias (22827458)
Sandro Rizoli (67238)
Ayman El-Menyar (440103)
Hassan Al-Thani (440106)
author_role author
dc.creator.none.fl_str_mv Ahmad Kloub (16855149)
Nuri Abdurraheim (22502795)
Ahmed Ramzee (22827422)
Naushad Ahmad Khan (6406973)
Mushreq Alani (22827425)
Suhail Hakim (9184946)
Zeenat Bakhsh (17883045)
Ibrahim Taha (14150361)
Basil Younis (14150349)
Gustav Strandvik (9756205)
Tariq Siddiqui (444882)
Yousif Ibrahim (22827428)
Mohamed Nasr (9637052)
Sherwan Khoschnau (16855143)
Khalid Ahmed (710040)
Ahad Kanbar (9184943)
Ashok Parchani (768895)
Amor Kilani (22827431)
Ala’ Suliman (22827434)
Motasem Awwad (22827437)
Sana’a Odeh (22827440)
Lady Faye Estalilla (22827443)
Ana Giurgea (22827446)
Abdul Nasar Avayil (22827449)
Jenalyn Salvador (22827452)
Jennely Dayandante (22827455)
Greesha Alias (22827458)
Sandro Rizoli (67238)
Ayman El-Menyar (440103)
Hassan Al-Thani (440106)
dc.date.none.fl_str_mv 2025-07-04T03:00:00Z
dc.identifier.none.fl_str_mv 10.1007/s00068-025-02920-9
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Intensivist_performed_compression_ultrasound_IPCUS_for_screening_and_early_detection_of_deep_venous_thrombosis_in_trauma_intensive_care_unit_a_prospective_study/30859838
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Cardiovascular medicine and haematology
Clinical sciences
Venous thromboembolism
Chemoprophylaxis
Trauma
Intensivists
Doppler ultrasound
dc.title.none.fl_str_mv Intensivist performed compression ultrasound (IPCUS) for screening and early detection of deep venous thrombosis in trauma intensive care unit: a prospective study
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3>Introduction</h3><p dir="ltr">Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a critical complication in trauma patients, contributing to considerable morbidity and mortality. Multiple factors in trauma pose a challenge to the early initiation of VTE chemoprophylaxis, thereby underscoring the benefit of early detection strategies for DVT. This study evaluated the feasibility of intensivist-performed Compression Ultrasound (IPCUS) for screening of proximal lower limbs for DVT in the trauma intensive care unit (TICU).</p><h3>Methods</h3><p dir="ltr">We conducted a prospective study at a level 1 trauma center from November 2021 to May 2023 to assess the utility of IPCUS at the TICU. The study cohort included 800 multi-trauma patients aged 14 years and older admitted to trauma intensive care and step-down units. IPCUS was performed using a three-point compression technique at multiple post-injury time points. Positive or equivocal findings were validated by duplex ultrasonography (DUS). Patients were followed up for one month after discharge.</p><h3>Results</h3><p dir="ltr">The cohort was predominantly male (94.2%), with a mean injury severity score of 20. The overall incidence of VTE within the cohort was 3%. VTE chemoprophylaxis was administered to 60% of patients within the first 48 h. IPCUS identified DVT in 10 patients, with a sensitivity of 89% and specificity of 100%. There was no clinical evidence of missed proximal lower limb DVTs. There was a moderate agreement (Cohen’s Kappa score of 0.46) between IPCUS and radiographer-performed DUS.</p><h3>Conclusion</h3><p dir="ltr">IPCUS is a feasible and effective screening method for proximal lower limb DVT in trauma patients with high diagnostic accuracy. Enhanced ultrasonography training for intensivists could further improve screening outcomes, reducing the number of equivocal cases. Larger studies are warranted to confirm these findings and establish standardized training protocols for IPCUS in trauma care settings.</p><h2>Other Information</h2><p dir="ltr">Published in: European Journal of Trauma and Emergency Surgery<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s00068-025-02920-9" target="_blank">https://dx.doi.org/10.1007/s00068-025-02920-9</a></p>
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spelling Intensivist performed compression ultrasound (IPCUS) for screening and early detection of deep venous thrombosis in trauma intensive care unit: a prospective studyAhmad Kloub (16855149)Nuri Abdurraheim (22502795)Ahmed Ramzee (22827422)Naushad Ahmad Khan (6406973)Mushreq Alani (22827425)Suhail Hakim (9184946)Zeenat Bakhsh (17883045)Ibrahim Taha (14150361)Basil Younis (14150349)Gustav Strandvik (9756205)Tariq Siddiqui (444882)Yousif Ibrahim (22827428)Mohamed Nasr (9637052)Sherwan Khoschnau (16855143)Khalid Ahmed (710040)Ahad Kanbar (9184943)Ashok Parchani (768895)Amor Kilani (22827431)Ala’ Suliman (22827434)Motasem Awwad (22827437)Sana’a Odeh (22827440)Lady Faye Estalilla (22827443)Ana Giurgea (22827446)Abdul Nasar Avayil (22827449)Jenalyn Salvador (22827452)Jennely Dayandante (22827455)Greesha Alias (22827458)Sandro Rizoli (67238)Ayman El-Menyar (440103)Hassan Al-Thani (440106)Biomedical and clinical sciencesCardiovascular medicine and haematologyClinical sciencesVenous thromboembolismChemoprophylaxisTraumaIntensivistsDoppler ultrasound<h3>Introduction</h3><p dir="ltr">Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a critical complication in trauma patients, contributing to considerable morbidity and mortality. Multiple factors in trauma pose a challenge to the early initiation of VTE chemoprophylaxis, thereby underscoring the benefit of early detection strategies for DVT. This study evaluated the feasibility of intensivist-performed Compression Ultrasound (IPCUS) for screening of proximal lower limbs for DVT in the trauma intensive care unit (TICU).</p><h3>Methods</h3><p dir="ltr">We conducted a prospective study at a level 1 trauma center from November 2021 to May 2023 to assess the utility of IPCUS at the TICU. The study cohort included 800 multi-trauma patients aged 14 years and older admitted to trauma intensive care and step-down units. IPCUS was performed using a three-point compression technique at multiple post-injury time points. Positive or equivocal findings were validated by duplex ultrasonography (DUS). Patients were followed up for one month after discharge.</p><h3>Results</h3><p dir="ltr">The cohort was predominantly male (94.2%), with a mean injury severity score of 20. The overall incidence of VTE within the cohort was 3%. VTE chemoprophylaxis was administered to 60% of patients within the first 48 h. IPCUS identified DVT in 10 patients, with a sensitivity of 89% and specificity of 100%. There was no clinical evidence of missed proximal lower limb DVTs. There was a moderate agreement (Cohen’s Kappa score of 0.46) between IPCUS and radiographer-performed DUS.</p><h3>Conclusion</h3><p dir="ltr">IPCUS is a feasible and effective screening method for proximal lower limb DVT in trauma patients with high diagnostic accuracy. Enhanced ultrasonography training for intensivists could further improve screening outcomes, reducing the number of equivocal cases. Larger studies are warranted to confirm these findings and establish standardized training protocols for IPCUS in trauma care settings.</p><h2>Other Information</h2><p dir="ltr">Published in: European Journal of Trauma and Emergency Surgery<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s00068-025-02920-9" target="_blank">https://dx.doi.org/10.1007/s00068-025-02920-9</a></p>2025-07-04T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s00068-025-02920-9https://figshare.com/articles/journal_contribution/Intensivist_performed_compression_ultrasound_IPCUS_for_screening_and_early_detection_of_deep_venous_thrombosis_in_trauma_intensive_care_unit_a_prospective_study/30859838CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/308598382025-07-04T03:00:00Z
spellingShingle Intensivist performed compression ultrasound (IPCUS) for screening and early detection of deep venous thrombosis in trauma intensive care unit: a prospective study
Ahmad Kloub (16855149)
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Clinical sciences
Venous thromboembolism
Chemoprophylaxis
Trauma
Intensivists
Doppler ultrasound
status_str publishedVersion
title Intensivist performed compression ultrasound (IPCUS) for screening and early detection of deep venous thrombosis in trauma intensive care unit: a prospective study
title_full Intensivist performed compression ultrasound (IPCUS) for screening and early detection of deep venous thrombosis in trauma intensive care unit: a prospective study
title_fullStr Intensivist performed compression ultrasound (IPCUS) for screening and early detection of deep venous thrombosis in trauma intensive care unit: a prospective study
title_full_unstemmed Intensivist performed compression ultrasound (IPCUS) for screening and early detection of deep venous thrombosis in trauma intensive care unit: a prospective study
title_short Intensivist performed compression ultrasound (IPCUS) for screening and early detection of deep venous thrombosis in trauma intensive care unit: a prospective study
title_sort Intensivist performed compression ultrasound (IPCUS) for screening and early detection of deep venous thrombosis in trauma intensive care unit: a prospective study
topic Biomedical and clinical sciences
Cardiovascular medicine and haematology
Clinical sciences
Venous thromboembolism
Chemoprophylaxis
Trauma
Intensivists
Doppler ultrasound