Automated insulin delivery for safe fasting and exercise during Ramadan in patients with type 1 diabetes: The active fast study
<h3>Aims</h3><p dir="ltr">To evaluate the safe and effective use of the MiniMed™ 780G Advanced Hybrid Closed-Loop system (AHCLS) in adults with<u> type 1 diabetes mellitus</u> (T1DM) during <u>Ramadan fasting</u> combined with structured Moderate-I...
محفوظ في:
| المؤلف الرئيسي: | |
|---|---|
| مؤلفون آخرون: | , , , , , , , , , , |
| منشور في: |
2025
|
| الموضوعات: | |
| الوسوم: |
إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
|
| _version_ | 1864513533584080896 |
|---|---|
| author | Khaled Baagar (7487690) |
| author2 | Hamda Ali (14115357) Fateen Ata (12217764) Kawsar Mohamud (22504061) Najla Al-Naimi (22504064) Arwa Alsaud (18060364) Hamad Al-Sharshani (22504067) Alaa Abd-Alrazaq (17430900) Arfan Ahmed (17541309) Sarah Aziz (17541312) Rawan Al Saad (22504070) Dabia Al-Mohanadi (17032269) |
| author2_role | author author author author author author author author author author author |
| author_facet | Khaled Baagar (7487690) Hamda Ali (14115357) Fateen Ata (12217764) Kawsar Mohamud (22504061) Najla Al-Naimi (22504064) Arwa Alsaud (18060364) Hamad Al-Sharshani (22504067) Alaa Abd-Alrazaq (17430900) Arfan Ahmed (17541309) Sarah Aziz (17541312) Rawan Al Saad (22504070) Dabia Al-Mohanadi (17032269) |
| author_role | author |
| dc.creator.none.fl_str_mv | Khaled Baagar (7487690) Hamda Ali (14115357) Fateen Ata (12217764) Kawsar Mohamud (22504061) Najla Al-Naimi (22504064) Arwa Alsaud (18060364) Hamad Al-Sharshani (22504067) Alaa Abd-Alrazaq (17430900) Arfan Ahmed (17541309) Sarah Aziz (17541312) Rawan Al Saad (22504070) Dabia Al-Mohanadi (17032269) |
| dc.date.none.fl_str_mv | 2025-06-28T12:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1016/j.diabres.2025.112353 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Automated_insulin_delivery_for_safe_fasting_and_exercise_during_Ramadan_in_patients_with_type_1_diabetes_The_active_fast_study/30455825 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Medical biochemistry and metabolomics Nutrition and dietetics Health sciences Public health Type 1 Diabetes System Ramadan Fasting MiniMed™ 780G Exercise Advanced Hybrid Closed-Loop System |
| dc.title.none.fl_str_mv | Automated insulin delivery for safe fasting and exercise during Ramadan in patients with type 1 diabetes: The active fast study |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Aims</h3><p dir="ltr">To evaluate the safe and effective use of the MiniMed™ 780G Advanced Hybrid Closed-Loop system (AHCLS) in adults with<u> type 1 diabetes mellitus</u> (T1DM) during <u>Ramadan fasting</u> combined with structured Moderate-Intensity Exercise (MIE) followed by the non-fasting month (Shawwal) with continued MIE. </p><h3>Methods</h3><p dir="ltr">This prospective, single-arm interventional study recruited 34 adults with T1DM using the MiniMed™ 780G. Participants performed MIE during non-fasting hours in Ramadan and continued it in Shawwal. Analyzed parameters included <u>glycemic control</u>, insulin requirements, usage of the MiniMed™ 780G system, metabolic parameters, and treatment satisfaction. </p><h3>Results</h3><p dir="ltr">Median time below range (<70 mg/dL) remained stable (1.0 %) across Ramadan and Shawwal (p = 0.39). Time in range (70–180 mg/dL) was significantly higher during Ramadan (70.5 %) than Shawwal (68.5 %, p = 0.0134), with a less median time above range(>180 mg/dL) in Ramadan (29 %) compared to Shawwal (30 %) (p = 0.0088). No severe hypoglycemia or <u>DKA</u> occurred. Participants demonstrated high treatment satisfaction and SmartGuard mode usage, with good adherence to fasting and exercise. </p><h3>Conclusions</h3><p dir="ltr">Adults with T1DM can safely fast during Ramadan and exercise using the MiniMed™ 780G to manage diabetes. Findings from this study build on the real-world evidence to enhance clinical guidelines for optimal T1DM care using advanced technology.</p><h2>Other Information</h2><p dir="ltr">Published in: Diabetes Research and Clinical Practice<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.diabres.2025.112353" target="_blank">https://dx.doi.org/10.1016/j.diabres.2025.112353</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_baa6834e05913db7e7e0e63365425274 |
| identifier_str_mv | 10.1016/j.diabres.2025.112353 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/30455825 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Automated insulin delivery for safe fasting and exercise during Ramadan in patients with type 1 diabetes: The active fast studyKhaled Baagar (7487690)Hamda Ali (14115357)Fateen Ata (12217764)Kawsar Mohamud (22504061)Najla Al-Naimi (22504064)Arwa Alsaud (18060364)Hamad Al-Sharshani (22504067)Alaa Abd-Alrazaq (17430900)Arfan Ahmed (17541309)Sarah Aziz (17541312)Rawan Al Saad (22504070)Dabia Al-Mohanadi (17032269)Biomedical and clinical sciencesMedical biochemistry and metabolomicsNutrition and dieteticsHealth sciencesPublic healthType 1 DiabetesSystemRamadanFastingMiniMed™ 780GExerciseAdvanced Hybrid Closed-Loop System<h3>Aims</h3><p dir="ltr">To evaluate the safe and effective use of the MiniMed™ 780G Advanced Hybrid Closed-Loop system (AHCLS) in adults with<u> type 1 diabetes mellitus</u> (T1DM) during <u>Ramadan fasting</u> combined with structured Moderate-Intensity Exercise (MIE) followed by the non-fasting month (Shawwal) with continued MIE. </p><h3>Methods</h3><p dir="ltr">This prospective, single-arm interventional study recruited 34 adults with T1DM using the MiniMed™ 780G. Participants performed MIE during non-fasting hours in Ramadan and continued it in Shawwal. Analyzed parameters included <u>glycemic control</u>, insulin requirements, usage of the MiniMed™ 780G system, metabolic parameters, and treatment satisfaction. </p><h3>Results</h3><p dir="ltr">Median time below range (<70 mg/dL) remained stable (1.0 %) across Ramadan and Shawwal (p = 0.39). Time in range (70–180 mg/dL) was significantly higher during Ramadan (70.5 %) than Shawwal (68.5 %, p = 0.0134), with a less median time above range(>180 mg/dL) in Ramadan (29 %) compared to Shawwal (30 %) (p = 0.0088). No severe hypoglycemia or <u>DKA</u> occurred. Participants demonstrated high treatment satisfaction and SmartGuard mode usage, with good adherence to fasting and exercise. </p><h3>Conclusions</h3><p dir="ltr">Adults with T1DM can safely fast during Ramadan and exercise using the MiniMed™ 780G to manage diabetes. Findings from this study build on the real-world evidence to enhance clinical guidelines for optimal T1DM care using advanced technology.</p><h2>Other Information</h2><p dir="ltr">Published in: Diabetes Research and Clinical Practice<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.diabres.2025.112353" target="_blank">https://dx.doi.org/10.1016/j.diabres.2025.112353</a></p>2025-06-28T12:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.diabres.2025.112353https://figshare.com/articles/journal_contribution/Automated_insulin_delivery_for_safe_fasting_and_exercise_during_Ramadan_in_patients_with_type_1_diabetes_The_active_fast_study/30455825CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/304558252025-06-28T12:00:00Z |
| spellingShingle | Automated insulin delivery for safe fasting and exercise during Ramadan in patients with type 1 diabetes: The active fast study Khaled Baagar (7487690) Biomedical and clinical sciences Medical biochemistry and metabolomics Nutrition and dietetics Health sciences Public health Type 1 Diabetes System Ramadan Fasting MiniMed™ 780G Exercise Advanced Hybrid Closed-Loop System |
| status_str | publishedVersion |
| title | Automated insulin delivery for safe fasting and exercise during Ramadan in patients with type 1 diabetes: The active fast study |
| title_full | Automated insulin delivery for safe fasting and exercise during Ramadan in patients with type 1 diabetes: The active fast study |
| title_fullStr | Automated insulin delivery for safe fasting and exercise during Ramadan in patients with type 1 diabetes: The active fast study |
| title_full_unstemmed | Automated insulin delivery for safe fasting and exercise during Ramadan in patients with type 1 diabetes: The active fast study |
| title_short | Automated insulin delivery for safe fasting and exercise during Ramadan in patients with type 1 diabetes: The active fast study |
| title_sort | Automated insulin delivery for safe fasting and exercise during Ramadan in patients with type 1 diabetes: The active fast study |
| topic | Biomedical and clinical sciences Medical biochemistry and metabolomics Nutrition and dietetics Health sciences Public health Type 1 Diabetes System Ramadan Fasting MiniMed™ 780G Exercise Advanced Hybrid Closed-Loop System |