Perinatal exposure to PFOS and sustained high-fat diet promote neurodevelopmental disorders via genomic reprogramming of pathways associated with neuromotor development

Perinatal exposure to PFOS and sustained high-fat diet promote neurodevelopmental disorders via genomic reprogramming of pathways associated with neuromotor development

<p>Perfluorooctanesulfonic acid (PFOS) is a neurotoxic widespread organic contaminant which affects several brain functions including memory, motor coordination and social activity. PFOS has the ability to traverse the placenta and the blood brain barrier (BBB) and cause weight gain in female...

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Bibliographic Details
Main Author: Issam Hmila (9239059) (author)
Other Authors: Jaunetta Hill (18255631) (author), Karim E. Shalaby (12267224) (author), Khalid Ouararhni (3145734) (author), Houari Abedsselem (18255634) (author), Seyed Mohamad Sadegh Modaresi (18255637) (author), Syed Waseem Bihaqi (18255640) (author), Emily Marques (9654981) (author), Anya Sondhi (18255643) (author), Angela L. Slitt (8806952) (author), Nasser H. Zawia (18255646) (author)
Published: 2024
Subjects:
Biomedical and clinical sciences
Pharmacology and pharmaceutical sciences
Environmental sciences
Pollution and contamination
Health sciences
Public health
PFOS
High fat diet
Tau pathology
Calcium pathway
MAPK pathway
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