Retrospective identification of medication related adverse events in the emergency medical services through the analysis of a patient safety register
<p dir="ltr">Adverse drug events encompass a wide range of potential unintended and harmful events, from adverse drug reactions to medication errors, many of which in retrospect, are considered preventable. However, the primary challenge towards reducing their burden lies in consiste...
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| مؤلفون آخرون: | , , , |
| منشور في: |
2022
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إضافة وسم
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| _version_ | 1864513547884560384 |
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| author | Ian Howard (2026753) |
| author2 | Ian Howland (18464452) Nicholas Castle (6011018) Loua Al Shaikh (6011021) Robert Owen (3247584) |
| author2_role | author author author author |
| author_facet | Ian Howard (2026753) Ian Howland (18464452) Nicholas Castle (6011018) Loua Al Shaikh (6011021) Robert Owen (3247584) |
| author_role | author |
| dc.creator.none.fl_str_mv | Ian Howard (2026753) Ian Howland (18464452) Nicholas Castle (6011018) Loua Al Shaikh (6011021) Robert Owen (3247584) |
| dc.date.none.fl_str_mv | 2022-02-16T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1038/s41598-022-06290-9 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Retrospective_identification_of_medication_related_adverse_events_in_the_emergency_medical_services_through_the_analysis_of_a_patient_safety_register/29098418 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Pharmacology and pharmaceutical sciences Health sciences Epidemiology Adverse drug events (ADEs) Medication errors Prehospital care Emergency medical services (EMS) Patient safety |
| dc.title.none.fl_str_mv | Retrospective identification of medication related adverse events in the emergency medical services through the analysis of a patient safety register |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Adverse drug events encompass a wide range of potential unintended and harmful events, from adverse drug reactions to medication errors, many of which in retrospect, are considered preventable. However, the primary challenge towards reducing their burden lies in consistently identifying and monitoring these occurrences, a challenge faced across the spectrum of healthcare, including the emergency medical services. The aim of this study was to identify and describe medication related adverse events (AEs) in the out-of-hospital setting. The medication components of a dedicated patient safety register were analysed and described for the period Jan 2017–Sept 2020. Univariate descriptive analysis was used to summarize and report on basic case and patient demographics, intervention related AEs, medication related AEs, and AE severity. Multivariable logistic regression was used to assess the odds of AE severity, by AE type. A total of 3475 patient records were assessed where 161 individual medication AEs were found in 150 (4.32%), 12 of which were categorised as harmful. Failure to provide a required medication was found to be the most common error (1.67%), followed by the administration of medications outside of prescribed practice guidelines (1.18%). There was evidence to suggest a 63% increase in crude odds of any AE severity [OR 1.63 (95% CI 1.03–2.6), p = 0.035] with the medication only AEs when compared to the intervention only AEs. Prehospital medication related adverse events remain a significant threat to patient safety in this setting and warrant greater widespread attention and future identification of strategies aimed at their reduction.</p><h2>Other Information</h2><p dir="ltr">Published in: Scientific Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1038/s41598-022-06290-9" target="_blank">https://dx.doi.org/10.1038/s41598-022-06290-9</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_bcbe6cdbd07e5343ecf039b51e9d6f94 |
| identifier_str_mv | 10.1038/s41598-022-06290-9 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/29098418 |
| publishDate | 2022 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Retrospective identification of medication related adverse events in the emergency medical services through the analysis of a patient safety registerIan Howard (2026753)Ian Howland (18464452)Nicholas Castle (6011018)Loua Al Shaikh (6011021)Robert Owen (3247584)Biomedical and clinical sciencesClinical sciencesPharmacology and pharmaceutical sciencesHealth sciencesEpidemiologyAdverse drug events (ADEs)Medication errorsPrehospital careEmergency medical services (EMS)Patient safety<p dir="ltr">Adverse drug events encompass a wide range of potential unintended and harmful events, from adverse drug reactions to medication errors, many of which in retrospect, are considered preventable. However, the primary challenge towards reducing their burden lies in consistently identifying and monitoring these occurrences, a challenge faced across the spectrum of healthcare, including the emergency medical services. The aim of this study was to identify and describe medication related adverse events (AEs) in the out-of-hospital setting. The medication components of a dedicated patient safety register were analysed and described for the period Jan 2017–Sept 2020. Univariate descriptive analysis was used to summarize and report on basic case and patient demographics, intervention related AEs, medication related AEs, and AE severity. Multivariable logistic regression was used to assess the odds of AE severity, by AE type. A total of 3475 patient records were assessed where 161 individual medication AEs were found in 150 (4.32%), 12 of which were categorised as harmful. Failure to provide a required medication was found to be the most common error (1.67%), followed by the administration of medications outside of prescribed practice guidelines (1.18%). There was evidence to suggest a 63% increase in crude odds of any AE severity [OR 1.63 (95% CI 1.03–2.6), p = 0.035] with the medication only AEs when compared to the intervention only AEs. Prehospital medication related adverse events remain a significant threat to patient safety in this setting and warrant greater widespread attention and future identification of strategies aimed at their reduction.</p><h2>Other Information</h2><p dir="ltr">Published in: Scientific Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1038/s41598-022-06290-9" target="_blank">https://dx.doi.org/10.1038/s41598-022-06290-9</a></p>2022-02-16T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1038/s41598-022-06290-9https://figshare.com/articles/journal_contribution/Retrospective_identification_of_medication_related_adverse_events_in_the_emergency_medical_services_through_the_analysis_of_a_patient_safety_register/29098418CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/290984182022-02-16T09:00:00Z |
| spellingShingle | Retrospective identification of medication related adverse events in the emergency medical services through the analysis of a patient safety register Ian Howard (2026753) Biomedical and clinical sciences Clinical sciences Pharmacology and pharmaceutical sciences Health sciences Epidemiology Adverse drug events (ADEs) Medication errors Prehospital care Emergency medical services (EMS) Patient safety |
| status_str | publishedVersion |
| title | Retrospective identification of medication related adverse events in the emergency medical services through the analysis of a patient safety register |
| title_full | Retrospective identification of medication related adverse events in the emergency medical services through the analysis of a patient safety register |
| title_fullStr | Retrospective identification of medication related adverse events in the emergency medical services through the analysis of a patient safety register |
| title_full_unstemmed | Retrospective identification of medication related adverse events in the emergency medical services through the analysis of a patient safety register |
| title_short | Retrospective identification of medication related adverse events in the emergency medical services through the analysis of a patient safety register |
| title_sort | Retrospective identification of medication related adverse events in the emergency medical services through the analysis of a patient safety register |
| topic | Biomedical and clinical sciences Clinical sciences Pharmacology and pharmaceutical sciences Health sciences Epidemiology Adverse drug events (ADEs) Medication errors Prehospital care Emergency medical services (EMS) Patient safety |