Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells <i>via</i> Tryptophan 2,3 Dioxygenase

Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells <i>via</i> Tryptophan 2,3 Dioxygenase

<p dir="ltr">In addition to its well-established immunosuppressive actions, tryptophan 2,3-dioxygenase (TDO) appears to elicit direct effects on tumor cell function. Although TDO has been associated with cancer stemness, its involvement in melanoma stem cell biology remains largely u...

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Bibliographic Details
Main Author: Marta Cecchi (21363581) (author)
Other Authors: Antonella Mannini (21363584) (author), Andrea Lapucci (470257) (author), Angela Silvano (21363587) (author), Matteo Lulli (7463885) (author), Cristina Luceri (3567536) (author), Mario D’Ambrosio (13172607) (author), Alberto Chiarugi (321191) (author), Ali H. Eid (5461829) (author), Astrid Parenti (578664) (author)
Published: 2022
Subjects:
Biomedical and clinical sciences
Immunology
Oncology and carcinogenesis
Pharmacology and pharmaceutical sciences
melanoma,
SK-MEL-28
A375
dexamethasone
glucocorticoids
tryptophan 2,3 dioxygenase
melanospheres
embryonic stem cell markers
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