Seroprevalence and factors associated with SARS-CoV-2 infection among healthcare workers: cross-sectional study

<h3>Background</h3><p dir="ltr">Healthcare workers (HCWs) are at a higher risk of contracting COVID-19 due to their close contact with infected patients. However, the true burden of COVID-19 among HCWs in Yemen is unknown due to the inadequate availability of healthcare a...

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Main Author: Watheq Thabet Taher (17541210) (author)
Other Authors: Amen A. Bawazir (17541213) (author), Talal A. Sallam (17541216) (author), Khaled Alsurimi (17541219) (author)
Published: 2023
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author Watheq Thabet Taher (17541210)
author2 Amen A. Bawazir (17541213)
Talal A. Sallam (17541216)
Khaled Alsurimi (17541219)
author2_role author
author
author
author_facet Watheq Thabet Taher (17541210)
Amen A. Bawazir (17541213)
Talal A. Sallam (17541216)
Khaled Alsurimi (17541219)
author_role author
dc.creator.none.fl_str_mv Watheq Thabet Taher (17541210)
Amen A. Bawazir (17541213)
Talal A. Sallam (17541216)
Khaled Alsurimi (17541219)
dc.date.none.fl_str_mv 2023-11-06T03:00:00Z
dc.identifier.none.fl_str_mv 10.1186/s12879-023-08760-5
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Seroprevalence_and_factors_associated_with_SARS-CoV-2_infection_among_healthcare_workers_cross-sectional_study/24717063
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Cardiovascular medicine and haematology
Clinical sciences
Health sciences
Epidemiology
Public health
Seroprevalence
COVID-19
SARS-CoV-2
Healthcare workers
COVID-19 vaccines
dc.title.none.fl_str_mv Seroprevalence and factors associated with SARS-CoV-2 infection among healthcare workers: cross-sectional study
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3>Background</h3><p dir="ltr">Healthcare workers (HCWs) are at a higher risk of contracting COVID-19 due to their close contact with infected patients. However, the true burden of COVID-19 among HCWs in Yemen is unknown due to the inadequate availability of healthcare and the subclinical nature of the disease. This study aims to estimate the seroprevalence of SARS-CoV-2 infection among HCWs in two Yemeni governorates and identify associated factors using a cross-sectional design.</p><h3>Method</h3><p dir="ltr">A total of 404 HCWs were surveyed from June 2022 to September 2022 in Lahj and AL-Dhalea hospitals. A self-administered questionnaire collected demographic data, COVID-19 infection history, and vaccination status. A total of 404 human sera were tested using a specific electrochemiluminescence immunoassay assay. Association analysis was conducted to identify associations between antibody prevalence and demographic and vaccine-related variables.</p><h3>Result</h3><p dir="ltr">The median age of the HCWs was 31 (Range 20–64) years, with 65.0% being male and 35.0% female. Of all HCWs, 94% were SARS-CoV-2 seropositive and 77.0% had no confirmed test of COVID-19-related symptoms. There was no significant association between seropositivity and demographic factors such as age, gender, occupation, or COVID-19 vaccination (P > 0.05).</p><h3>Conclusion</h3><p dir="ltr">The seroprevalence of SARS-CoV-2 was high among HCWs in Yemen, primarily due to natural infection rather than vaccination. Compliance with infection prevention and control measures did not significantly affect seropositivity. This study highlights the need for improved healthcare systems and resources to reduce the burden of COVID-19 and promote infection prevention and control (IPC) measures among HCWs in Yemen.</p><h2>Other Information</h2><p dir="ltr">Published in: BMC Infectious Diseases<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1186/s12879-023-08760-5" target="_blank">https://dx.doi.org/10.1186/s12879-023-08760-5</a></p>
eu_rights_str_mv openAccess
id Manara2_c14c516520bfa22cdef62b2c26a43a61
identifier_str_mv 10.1186/s12879-023-08760-5
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/24717063
publishDate 2023
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rights_invalid_str_mv CC BY 4.0
spelling Seroprevalence and factors associated with SARS-CoV-2 infection among healthcare workers: cross-sectional studyWatheq Thabet Taher (17541210)Amen A. Bawazir (17541213)Talal A. Sallam (17541216)Khaled Alsurimi (17541219)Biomedical and clinical sciencesCardiovascular medicine and haematologyClinical sciencesHealth sciencesEpidemiologyPublic healthSeroprevalenceCOVID-19SARS-CoV-2Healthcare workersCOVID-19 vaccines<h3>Background</h3><p dir="ltr">Healthcare workers (HCWs) are at a higher risk of contracting COVID-19 due to their close contact with infected patients. However, the true burden of COVID-19 among HCWs in Yemen is unknown due to the inadequate availability of healthcare and the subclinical nature of the disease. This study aims to estimate the seroprevalence of SARS-CoV-2 infection among HCWs in two Yemeni governorates and identify associated factors using a cross-sectional design.</p><h3>Method</h3><p dir="ltr">A total of 404 HCWs were surveyed from June 2022 to September 2022 in Lahj and AL-Dhalea hospitals. A self-administered questionnaire collected demographic data, COVID-19 infection history, and vaccination status. A total of 404 human sera were tested using a specific electrochemiluminescence immunoassay assay. Association analysis was conducted to identify associations between antibody prevalence and demographic and vaccine-related variables.</p><h3>Result</h3><p dir="ltr">The median age of the HCWs was 31 (Range 20–64) years, with 65.0% being male and 35.0% female. Of all HCWs, 94% were SARS-CoV-2 seropositive and 77.0% had no confirmed test of COVID-19-related symptoms. There was no significant association between seropositivity and demographic factors such as age, gender, occupation, or COVID-19 vaccination (P > 0.05).</p><h3>Conclusion</h3><p dir="ltr">The seroprevalence of SARS-CoV-2 was high among HCWs in Yemen, primarily due to natural infection rather than vaccination. Compliance with infection prevention and control measures did not significantly affect seropositivity. This study highlights the need for improved healthcare systems and resources to reduce the burden of COVID-19 and promote infection prevention and control (IPC) measures among HCWs in Yemen.</p><h2>Other Information</h2><p dir="ltr">Published in: BMC Infectious Diseases<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1186/s12879-023-08760-5" target="_blank">https://dx.doi.org/10.1186/s12879-023-08760-5</a></p>2023-11-06T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1186/s12879-023-08760-5https://figshare.com/articles/journal_contribution/Seroprevalence_and_factors_associated_with_SARS-CoV-2_infection_among_healthcare_workers_cross-sectional_study/24717063CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/247170632023-11-06T03:00:00Z
spellingShingle Seroprevalence and factors associated with SARS-CoV-2 infection among healthcare workers: cross-sectional study
Watheq Thabet Taher (17541210)
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Clinical sciences
Health sciences
Epidemiology
Public health
Seroprevalence
COVID-19
SARS-CoV-2
Healthcare workers
COVID-19 vaccines
status_str publishedVersion
title Seroprevalence and factors associated with SARS-CoV-2 infection among healthcare workers: cross-sectional study
title_full Seroprevalence and factors associated with SARS-CoV-2 infection among healthcare workers: cross-sectional study
title_fullStr Seroprevalence and factors associated with SARS-CoV-2 infection among healthcare workers: cross-sectional study
title_full_unstemmed Seroprevalence and factors associated with SARS-CoV-2 infection among healthcare workers: cross-sectional study
title_short Seroprevalence and factors associated with SARS-CoV-2 infection among healthcare workers: cross-sectional study
title_sort Seroprevalence and factors associated with SARS-CoV-2 infection among healthcare workers: cross-sectional study
topic Biomedical and clinical sciences
Cardiovascular medicine and haematology
Clinical sciences
Health sciences
Epidemiology
Public health
Seroprevalence
COVID-19
SARS-CoV-2
Healthcare workers
COVID-19 vaccines