Stem cell library screen identified ruxolitinib as regulator of osteoblastic differentiation of human skeletal stem cells

Stem cell library screen identified ruxolitinib as regulator of osteoblastic differentiation of human skeletal stem cells

<h3>Background</h3><p dir="ltr">Better understanding of the signaling pathways that regulate human bone marrow stromal stem cell (hBMSC) differentiation into bone-forming osteoblasts is crucial for their clinical use in regenerative medicine. Chemical biology approaches u...

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Bibliographic Details
Main Author: Nihal AlMuraikhi (6002234) (author)
Other Authors: Dalia Ali (6002237) (author), Aliah Alshanwani (6002240) (author), Radhakrishnan Vishnubalaji (3563306) (author), Muthurangan Manikandan (6002243) (author), Muhammad Atteya (6002246) (author), Abdulaziz Siyal (6002249) (author), Musaad Alfayez (3571736) (author), Abdullah Aldahmash (3563300) (author), Moustapha Kassem (101848) (author), Nehad M. Alajez (7397276) (author)
Published: 2018
Subjects:
Biological sciences
Biochemistry and cell biology
Biomedical and clinical sciences
Medical biotechnology
Ruxolitinib
Osteoblast Differentiation
hBMSCs
Mineralized Matrix Formation
Chemical Biology Approach
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