Prevalence of newly detected diabetes in pregnancy in Qatar, using universal screening

<h3>Background</h3><p dir="ltr">Diabetes first detected during pregnancy is currently divided into gestational diabetes mellitus (GDM) and diabetes mellitus (DM)- most of which are type 2 DM (T2DM). This study aims to define the prevalence and outcomes of diabetes first d...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Mohammed Bashir (5593550) (author)
مؤلفون آخرون: Manar E. Abdel-Rahman (16122263) (author), Mahmoud Aboulfotouh (5593556) (author), Fatin Eltaher (5593559) (author), Khalid Omar (5593562) (author), Isaac Babarinsa (5593565) (author), Kwabena Appiah-Sakyi (5593568) (author), Tarek Sharaf (5593571) (author), Eman Azzam (5593574) (author), Mohammad Abukhalil (5593577) (author), Malika Boumedjane (5593580) (author), Wigdan Yousif (5593583) (author), Warda Ahmed (5593586) (author), Sadaf Khan (129161) (author), Justin C. Konje (374363) (author), Abdul-Badi Abou-Samra (3411167) (author)
منشور في: 2018
الموضوعات:
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author Mohammed Bashir (5593550)
author2 Manar E. Abdel-Rahman (16122263)
Mahmoud Aboulfotouh (5593556)
Fatin Eltaher (5593559)
Khalid Omar (5593562)
Isaac Babarinsa (5593565)
Kwabena Appiah-Sakyi (5593568)
Tarek Sharaf (5593571)
Eman Azzam (5593574)
Mohammad Abukhalil (5593577)
Malika Boumedjane (5593580)
Wigdan Yousif (5593583)
Warda Ahmed (5593586)
Sadaf Khan (129161)
Justin C. Konje (374363)
Abdul-Badi Abou-Samra (3411167)
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author_facet Mohammed Bashir (5593550)
Manar E. Abdel-Rahman (16122263)
Mahmoud Aboulfotouh (5593556)
Fatin Eltaher (5593559)
Khalid Omar (5593562)
Isaac Babarinsa (5593565)
Kwabena Appiah-Sakyi (5593568)
Tarek Sharaf (5593571)
Eman Azzam (5593574)
Mohammad Abukhalil (5593577)
Malika Boumedjane (5593580)
Wigdan Yousif (5593583)
Warda Ahmed (5593586)
Sadaf Khan (129161)
Justin C. Konje (374363)
Abdul-Badi Abou-Samra (3411167)
author_role author
dc.creator.none.fl_str_mv Mohammed Bashir (5593550)
Manar E. Abdel-Rahman (16122263)
Mahmoud Aboulfotouh (5593556)
Fatin Eltaher (5593559)
Khalid Omar (5593562)
Isaac Babarinsa (5593565)
Kwabena Appiah-Sakyi (5593568)
Tarek Sharaf (5593571)
Eman Azzam (5593574)
Mohammad Abukhalil (5593577)
Malika Boumedjane (5593580)
Wigdan Yousif (5593583)
Warda Ahmed (5593586)
Sadaf Khan (129161)
Justin C. Konje (374363)
Abdul-Badi Abou-Samra (3411167)
dc.date.none.fl_str_mv 2018-08-03T03:00:00Z
dc.identifier.none.fl_str_mv 10.1371/journal.pone.0201247
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Prevalence_of_newly_detected_diabetes_in_pregnancy_in_Qatar_using_universal_screening/25331308
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Clinical sciences
Medical biochemistry and metabolomics
Reproductive medicine
diabetes
pregnancy
Qatar
gestational diabetes mellitus (GDM)
diabetes mellitus (DM)
dc.title.none.fl_str_mv Prevalence of newly detected diabetes in pregnancy in Qatar, using universal screening
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3>Background</h3><p dir="ltr">Diabetes first detected during pregnancy is currently divided into gestational diabetes mellitus (GDM) and diabetes mellitus (DM)- most of which are type 2 DM (T2DM). This study aims to define the prevalence and outcomes of diabetes first detected in pregnancy based on 75-gram oral glucose tolerance test (OGTT)using the recent WHO/IADPSG guidelines in a high-risk population.</p><h3>Methods</h3><p dir="ltr">This is a retrospective study that included all patients who underwent a 75 g (OGTT) between Jan 2016 and Apr 2016 and excluded patients with known pre-conception diabetes.</p><h3>Results</h3><p dir="ltr">The overall prevalence of newly detected diabetes in pregnancy among the 2000 patients who fulfilled the inclusion/exclusion criteria was 24.0% (95% CI 22.1–25.9) of which T2DM was 2.5% (95% CI 1.9–3.3), and GDM was 21.5% (95% CI 19.7–23.3). The prevalence of newly detected diabetes in pregnancy was similar among the different ethnic groups.</p><p><br></p><p dir="ltr">The T2DM group was older (mean age in years was 34 ±5.7 vs 31.7±5.7 vs 29.7 ±5.7, p<0.001); and has a higher mean BMI (32.4±6.4 kg/m2 vs 31.7±6.2 kg/m2 vs 29.7± 6.2 kg/m2, p< 0.01) than the GDM and the non-DM groups, respectively. The frequency of pre-eclampsia, pre-term delivery, Caesarean-section, macrosomia, LGA and neonatal ICU admissions were significantly higher in the T2DM group compared to GDM and non-DM groups.</p><h3>Conclusion</h3><p dir="ltr">Diabetes first detected in pregnancy is equally prevalent among the various ethnic groups residing in Qatar. Newly detected T2DM carries a higher risk of poor pregnancy outcomes; stressing the importance of proper classification of cases of newly detected diabetes in pregnancy.</p><h2>Other Information</h2><p dir="ltr">Published in: PLOS ONE<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1371/journal.pone.0201247" target="_blank">https://dx.doi.org/10.1371/journal.pone.0201247</a></p>
eu_rights_str_mv openAccess
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network_acronym_str Manara2
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publishDate 2018
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spelling Prevalence of newly detected diabetes in pregnancy in Qatar, using universal screeningMohammed Bashir (5593550)Manar E. Abdel-Rahman (16122263)Mahmoud Aboulfotouh (5593556)Fatin Eltaher (5593559)Khalid Omar (5593562)Isaac Babarinsa (5593565)Kwabena Appiah-Sakyi (5593568)Tarek Sharaf (5593571)Eman Azzam (5593574)Mohammad Abukhalil (5593577)Malika Boumedjane (5593580)Wigdan Yousif (5593583)Warda Ahmed (5593586)Sadaf Khan (129161)Justin C. Konje (374363)Abdul-Badi Abou-Samra (3411167)Biomedical and clinical sciencesClinical sciencesMedical biochemistry and metabolomicsReproductive medicinediabetespregnancyQatargestational diabetes mellitus (GDM)diabetes mellitus (DM)<h3>Background</h3><p dir="ltr">Diabetes first detected during pregnancy is currently divided into gestational diabetes mellitus (GDM) and diabetes mellitus (DM)- most of which are type 2 DM (T2DM). This study aims to define the prevalence and outcomes of diabetes first detected in pregnancy based on 75-gram oral glucose tolerance test (OGTT)using the recent WHO/IADPSG guidelines in a high-risk population.</p><h3>Methods</h3><p dir="ltr">This is a retrospective study that included all patients who underwent a 75 g (OGTT) between Jan 2016 and Apr 2016 and excluded patients with known pre-conception diabetes.</p><h3>Results</h3><p dir="ltr">The overall prevalence of newly detected diabetes in pregnancy among the 2000 patients who fulfilled the inclusion/exclusion criteria was 24.0% (95% CI 22.1–25.9) of which T2DM was 2.5% (95% CI 1.9–3.3), and GDM was 21.5% (95% CI 19.7–23.3). The prevalence of newly detected diabetes in pregnancy was similar among the different ethnic groups.</p><p><br></p><p dir="ltr">The T2DM group was older (mean age in years was 34 ±5.7 vs 31.7±5.7 vs 29.7 ±5.7, p<0.001); and has a higher mean BMI (32.4±6.4 kg/m2 vs 31.7±6.2 kg/m2 vs 29.7± 6.2 kg/m2, p< 0.01) than the GDM and the non-DM groups, respectively. The frequency of pre-eclampsia, pre-term delivery, Caesarean-section, macrosomia, LGA and neonatal ICU admissions were significantly higher in the T2DM group compared to GDM and non-DM groups.</p><h3>Conclusion</h3><p dir="ltr">Diabetes first detected in pregnancy is equally prevalent among the various ethnic groups residing in Qatar. Newly detected T2DM carries a higher risk of poor pregnancy outcomes; stressing the importance of proper classification of cases of newly detected diabetes in pregnancy.</p><h2>Other Information</h2><p dir="ltr">Published in: PLOS ONE<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1371/journal.pone.0201247" target="_blank">https://dx.doi.org/10.1371/journal.pone.0201247</a></p>2018-08-03T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1371/journal.pone.0201247https://figshare.com/articles/journal_contribution/Prevalence_of_newly_detected_diabetes_in_pregnancy_in_Qatar_using_universal_screening/25331308CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/253313082018-08-03T03:00:00Z
spellingShingle Prevalence of newly detected diabetes in pregnancy in Qatar, using universal screening
Mohammed Bashir (5593550)
Biomedical and clinical sciences
Clinical sciences
Medical biochemistry and metabolomics
Reproductive medicine
diabetes
pregnancy
Qatar
gestational diabetes mellitus (GDM)
diabetes mellitus (DM)
status_str publishedVersion
title Prevalence of newly detected diabetes in pregnancy in Qatar, using universal screening
title_full Prevalence of newly detected diabetes in pregnancy in Qatar, using universal screening
title_fullStr Prevalence of newly detected diabetes in pregnancy in Qatar, using universal screening
title_full_unstemmed Prevalence of newly detected diabetes in pregnancy in Qatar, using universal screening
title_short Prevalence of newly detected diabetes in pregnancy in Qatar, using universal screening
title_sort Prevalence of newly detected diabetes in pregnancy in Qatar, using universal screening
topic Biomedical and clinical sciences
Clinical sciences
Medical biochemistry and metabolomics
Reproductive medicine
diabetes
pregnancy
Qatar
gestational diabetes mellitus (GDM)
diabetes mellitus (DM)