Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens?
<p>Obesity is a risk for many different cancers. Laparoscopic sleeve gastrectomy (LSG) is common, and benign or pre-malignant histopathology types are reported in the removed gastric specimens. We assessed whether higher BMI was associated with certain benign or pre-malignant histopathological...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | , |
| Published: |
2019
|
| Subjects: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1864513567453085696 |
|---|---|
| author | Tamer Saafan (14151819) |
| author2 | Walid El Ansari (93732) Moataz Bashah (14148867) |
| author2_role | author author |
| author_facet | Tamer Saafan (14151819) Walid El Ansari (93732) Moataz Bashah (14148867) |
| author_role | author |
| dc.creator.none.fl_str_mv | Tamer Saafan (14151819) Walid El Ansari (93732) Moataz Bashah (14148867) |
| dc.date.none.fl_str_mv | 2019-04-15T06:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1007/s11695-019-03801-y |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Compared_to_What_Is_BMI_Associated_with_Histopathological_Changes_in_Laparoscopic_Sleeve_Gastrectomy_Specimens_/21597594 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Medical biochemistry and metabolomics Nutrition and dietetics Nutrition and Dietetics Endocrinology, Diabetes and Metabolism Surgery |
| dc.title.none.fl_str_mv | Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens? |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p>Obesity is a risk for many different cancers. Laparoscopic sleeve gastrectomy (LSG) is common, and benign or pre-malignant histopathology types are reported in the removed gastric specimens. We assessed whether higher BMI was associated with certain benign or pre-malignant histopathological changes. Retrospective chart review of all primary LSG patients (N = 1555). Demographic, clinical, and LSG histopathology data were retrieved. BMI of patients with specific benign or pre-malignant conditions in their gastric specimens was compared with the BMI of the rest of the patients with abnormal histopathology specimens and also compared with the BMI of patients with normal control specimens. Females comprised 70% of the patients. Mean BMI were 46.3 (females) and 48 (males). Normal LSG specimens comprised 52%. Most common abnormal histopathologies were chronic inactive gastritis (33%), chronic active gastritis (6.8%), follicular gastritis (2.7%), lymphoid aggregates (2.2%), intestinal metaplasia (1.4%) and GIST (0.7%). After controlling for confounders (age, gender, H. pylori, diabetes mellitus type 2, hypertension), no significant association was observed between the BMI of patients with specific benign or pre-malignant histopathology compared with the BMI of the rest of the patients with abnormal histopathologies and compared to the BMI of patients with normal histopathologies. When confounders were taken into account, there appeared no significant associations between the BMI of patients with specific benign or pre-malignant histopathology compared with the BMI of the rest of the patients with abnormal histopathologies and compared to the BMI of patients with normal histopathologies of their gastric specimens. There was a very weak correlation between BMI and other covariates.</p><h2>Other Information</h2> <p> Published in: Obesity Surgery<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s11695-019-03801-y" target="_blank">http://dx.doi.org/10.1007/s11695-019-03801-y</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_cb38e687df236d084b2148b72e80bd34 |
| identifier_str_mv | 10.1007/s11695-019-03801-y |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/21597594 |
| publishDate | 2019 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens?Tamer Saafan (14151819)Walid El Ansari (93732)Moataz Bashah (14148867)Biomedical and clinical sciencesMedical biochemistry and metabolomicsNutrition and dieteticsNutrition and DieteticsEndocrinology, Diabetes and MetabolismSurgery<p>Obesity is a risk for many different cancers. Laparoscopic sleeve gastrectomy (LSG) is common, and benign or pre-malignant histopathology types are reported in the removed gastric specimens. We assessed whether higher BMI was associated with certain benign or pre-malignant histopathological changes. Retrospective chart review of all primary LSG patients (N = 1555). Demographic, clinical, and LSG histopathology data were retrieved. BMI of patients with specific benign or pre-malignant conditions in their gastric specimens was compared with the BMI of the rest of the patients with abnormal histopathology specimens and also compared with the BMI of patients with normal control specimens. Females comprised 70% of the patients. Mean BMI were 46.3 (females) and 48 (males). Normal LSG specimens comprised 52%. Most common abnormal histopathologies were chronic inactive gastritis (33%), chronic active gastritis (6.8%), follicular gastritis (2.7%), lymphoid aggregates (2.2%), intestinal metaplasia (1.4%) and GIST (0.7%). After controlling for confounders (age, gender, H. pylori, diabetes mellitus type 2, hypertension), no significant association was observed between the BMI of patients with specific benign or pre-malignant histopathology compared with the BMI of the rest of the patients with abnormal histopathologies and compared to the BMI of patients with normal histopathologies. When confounders were taken into account, there appeared no significant associations between the BMI of patients with specific benign or pre-malignant histopathology compared with the BMI of the rest of the patients with abnormal histopathologies and compared to the BMI of patients with normal histopathologies of their gastric specimens. There was a very weak correlation between BMI and other covariates.</p><h2>Other Information</h2> <p> Published in: Obesity Surgery<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s11695-019-03801-y" target="_blank">http://dx.doi.org/10.1007/s11695-019-03801-y</a></p>2019-04-15T06:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s11695-019-03801-yhttps://figshare.com/articles/journal_contribution/Compared_to_What_Is_BMI_Associated_with_Histopathological_Changes_in_Laparoscopic_Sleeve_Gastrectomy_Specimens_/21597594CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/215975942019-04-15T06:00:00Z |
| spellingShingle | Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens? Tamer Saafan (14151819) Biomedical and clinical sciences Medical biochemistry and metabolomics Nutrition and dietetics Nutrition and Dietetics Endocrinology, Diabetes and Metabolism Surgery |
| status_str | publishedVersion |
| title | Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens? |
| title_full | Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens? |
| title_fullStr | Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens? |
| title_full_unstemmed | Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens? |
| title_short | Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens? |
| title_sort | Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens? |
| topic | Biomedical and clinical sciences Medical biochemistry and metabolomics Nutrition and dietetics Nutrition and Dietetics Endocrinology, Diabetes and Metabolism Surgery |