The Role of Apolipoproteins in the Commonest Cancers: A Review
<div><p>Apolipoproteins (APOs) are vital structural components of plasma lipoproteins that are involved in lipid metabolism and transport. Recent studies have reported an association between apolipoprotein dysregulation and the onset of a variety of human cancers; however, the role of ce...
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2023
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| _version_ | 1864513519866609664 |
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| author | Nour M. Darwish (18192730) |
| author2 | Mooza Kh. Al-Hail (18192733) Youssef Mohamed (10869765) Rafif Al Saady (18192736) Sara Mohsen (18192739) Amna Zar (18192742) Layla Al-Mansoori (9522518) Shona Pedersen (2792278) |
| author2_role | author author author author author author author |
| author_facet | Nour M. Darwish (18192730) Mooza Kh. Al-Hail (18192733) Youssef Mohamed (10869765) Rafif Al Saady (18192736) Sara Mohsen (18192739) Amna Zar (18192742) Layla Al-Mansoori (9522518) Shona Pedersen (2792278) |
| author_role | author |
| dc.creator.none.fl_str_mv | Nour M. Darwish (18192730) Mooza Kh. Al-Hail (18192733) Youssef Mohamed (10869765) Rafif Al Saady (18192736) Sara Mohsen (18192739) Amna Zar (18192742) Layla Al-Mansoori (9522518) Shona Pedersen (2792278) |
| dc.date.none.fl_str_mv | 2023-11-24T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.3390/cancers15235565 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/The_Role_of_Apolipoproteins_in_the_Commonest_Cancers_A_Review/25449430 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Oncology and carcinogenesis apolipoproteins carcinogenesis gene expression therapeutics |
| dc.title.none.fl_str_mv | The Role of Apolipoproteins in the Commonest Cancers: A Review |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <div><p>Apolipoproteins (APOs) are vital structural components of plasma lipoproteins that are involved in lipid metabolism and transport. Recent studies have reported an association between apolipoprotein dysregulation and the onset of a variety of human cancers; however, the role of certain APOs in cancer development remains unknown. Based on recent work, we hypothesize that APOs might be involved in the onset of cancer, with a focus on the most common cancers, including breast, lung, gynecological, colorectal, thyroid, gastric, pancreatic, hepatic, and prostate cancers. This review will focus on the evidence supporting this hypothesis, the mechanisms linking APOs to the onset of cancer, and the potential clinical relevance of its various inhibitors.</p><p> </p></div><h2>Other Information</h2> <p> Published in: Cancers<br> License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/cancers15235565" target="_blank">https://dx.doi.org/10.3390/cancers15235565</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_cd98a01ace6601cdca61707fe31cd5e3 |
| identifier_str_mv | 10.3390/cancers15235565 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/25449430 |
| publishDate | 2023 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | The Role of Apolipoproteins in the Commonest Cancers: A ReviewNour M. Darwish (18192730)Mooza Kh. Al-Hail (18192733)Youssef Mohamed (10869765)Rafif Al Saady (18192736)Sara Mohsen (18192739)Amna Zar (18192742)Layla Al-Mansoori (9522518)Shona Pedersen (2792278)Biomedical and clinical sciencesOncology and carcinogenesisapolipoproteinscarcinogenesisgene expressiontherapeutics<div><p>Apolipoproteins (APOs) are vital structural components of plasma lipoproteins that are involved in lipid metabolism and transport. Recent studies have reported an association between apolipoprotein dysregulation and the onset of a variety of human cancers; however, the role of certain APOs in cancer development remains unknown. Based on recent work, we hypothesize that APOs might be involved in the onset of cancer, with a focus on the most common cancers, including breast, lung, gynecological, colorectal, thyroid, gastric, pancreatic, hepatic, and prostate cancers. This review will focus on the evidence supporting this hypothesis, the mechanisms linking APOs to the onset of cancer, and the potential clinical relevance of its various inhibitors.</p><p> </p></div><h2>Other Information</h2> <p> Published in: Cancers<br> License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/cancers15235565" target="_blank">https://dx.doi.org/10.3390/cancers15235565</a></p>2023-11-24T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.3390/cancers15235565https://figshare.com/articles/journal_contribution/The_Role_of_Apolipoproteins_in_the_Commonest_Cancers_A_Review/25449430CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/254494302023-11-24T03:00:00Z |
| spellingShingle | The Role of Apolipoproteins in the Commonest Cancers: A Review Nour M. Darwish (18192730) Biomedical and clinical sciences Oncology and carcinogenesis apolipoproteins carcinogenesis gene expression therapeutics |
| status_str | publishedVersion |
| title | The Role of Apolipoproteins in the Commonest Cancers: A Review |
| title_full | The Role of Apolipoproteins in the Commonest Cancers: A Review |
| title_fullStr | The Role of Apolipoproteins in the Commonest Cancers: A Review |
| title_full_unstemmed | The Role of Apolipoproteins in the Commonest Cancers: A Review |
| title_short | The Role of Apolipoproteins in the Commonest Cancers: A Review |
| title_sort | The Role of Apolipoproteins in the Commonest Cancers: A Review |
| topic | Biomedical and clinical sciences Oncology and carcinogenesis apolipoproteins carcinogenesis gene expression therapeutics |