Medicinal Phytocompounds as Potential Inhibitors of p300-HIF1α Interaction: A Structure-Based Screening and Molecular Dynamics Simulation Study
<h3>Background</h3><p dir="ltr">Hypoxia plays a key role in cancer progression, mainly by stabilizing and activating hypoxia-inducible factor-1 (HIF-1). For HIF-1 to function under low oxygen conditions, it must interact with the transcriptional coactivator p300, a critic...
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| Main Author: | Muhammad Suleman (3829027) (author) |
|---|---|
| Other Authors: | Abrar Mohammad Sayaf (11644294) (author), Sohail Aftab (22443284) (author), Mohammed Alissa (18607830) (author), Abdullah Alghamdi (14375904) (author), Suad A. Alghamdi (21998691) (author), Mohammed A. Alshehri (18696547) (author), Kar Kheng Yeoh (1933633) (author), Sergio Crovella (20921252) (author), Abdullah Shaito (20545181) (author) |
| Published: |
2025
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| Subjects: | |
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