Potential Medical Applications of Chitooligosaccharides
<p dir="ltr">Chitooligosaccharides, also known as chitosan oligomers or chitooligomers, are made up of chitosan with a degree of polymerization (DP) that is less than 20 and an average molecular weight (MW) that is lower than 3.9 kDa. COS can be produced through enzymatic conversions...
محفوظ في:
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| منشور في: |
2022
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| _version_ | 1864513547841568768 |
|---|---|
| author | Sukumaran Anil (14158935) |
| author_facet | Sukumaran Anil (14158935) |
| author_role | author |
| dc.creator.none.fl_str_mv | Sukumaran Anil (14158935) |
| dc.date.none.fl_str_mv | 2022-08-29T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.3390/polym14173558 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Potential_Medical_Applications_of_Chitooligosaccharides/29098511 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Medical biotechnology Pharmacology and pharmaceutical sciences chitooligosaccharides chitin chitosan anti-inflammatory antioxidant tissue engineering wound healing antimicrobial drug delivery antitumor |
| dc.title.none.fl_str_mv | Potential Medical Applications of Chitooligosaccharides |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Chitooligosaccharides, also known as chitosan oligomers or chitooligomers, are made up of chitosan with a degree of polymerization (DP) that is less than 20 and an average molecular weight (MW) that is lower than 3.9 kDa. COS can be produced through enzymatic conversions using chitinases, physical and chemical applications, or a combination of these strategies. COS is of significant interest for pharmacological and medical applications due to its increased water solubility and non-toxicity, with a wide range of bioactivities, including antibacterial, anti-inflammatory, anti-obesity, neuroprotective, anticancer, and antioxidant effects. This review aims to outline the recent advances and potential applications of COS in various diseases and conditions based on the available literature, mainly from preclinical research. The prospects of further in vivo studies and translational research on COS in the medical field are highlighted.</p><h2>Other Information</h2><p dir="ltr">Published in: Polymers<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/polym14173558" target="_blank">https://dx.doi.org/10.3390/polym14173558</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_cfc72a1930ffb76f5a575834b5a6f7c8 |
| identifier_str_mv | 10.3390/polym14173558 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/29098511 |
| publishDate | 2022 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Potential Medical Applications of ChitooligosaccharidesSukumaran Anil (14158935)Biomedical and clinical sciencesMedical biotechnologyPharmacology and pharmaceutical scienceschitooligosaccharideschitinchitosananti-inflammatoryantioxidanttissue engineeringwound healingantimicrobialdrug deliveryantitumor<p dir="ltr">Chitooligosaccharides, also known as chitosan oligomers or chitooligomers, are made up of chitosan with a degree of polymerization (DP) that is less than 20 and an average molecular weight (MW) that is lower than 3.9 kDa. COS can be produced through enzymatic conversions using chitinases, physical and chemical applications, or a combination of these strategies. COS is of significant interest for pharmacological and medical applications due to its increased water solubility and non-toxicity, with a wide range of bioactivities, including antibacterial, anti-inflammatory, anti-obesity, neuroprotective, anticancer, and antioxidant effects. This review aims to outline the recent advances and potential applications of COS in various diseases and conditions based on the available literature, mainly from preclinical research. The prospects of further in vivo studies and translational research on COS in the medical field are highlighted.</p><h2>Other Information</h2><p dir="ltr">Published in: Polymers<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/polym14173558" target="_blank">https://dx.doi.org/10.3390/polym14173558</a></p>2022-08-29T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.3390/polym14173558https://figshare.com/articles/journal_contribution/Potential_Medical_Applications_of_Chitooligosaccharides/29098511CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/290985112022-08-29T09:00:00Z |
| spellingShingle | Potential Medical Applications of Chitooligosaccharides Sukumaran Anil (14158935) Biomedical and clinical sciences Medical biotechnology Pharmacology and pharmaceutical sciences chitooligosaccharides chitin chitosan anti-inflammatory antioxidant tissue engineering wound healing antimicrobial drug delivery antitumor |
| status_str | publishedVersion |
| title | Potential Medical Applications of Chitooligosaccharides |
| title_full | Potential Medical Applications of Chitooligosaccharides |
| title_fullStr | Potential Medical Applications of Chitooligosaccharides |
| title_full_unstemmed | Potential Medical Applications of Chitooligosaccharides |
| title_short | Potential Medical Applications of Chitooligosaccharides |
| title_sort | Potential Medical Applications of Chitooligosaccharides |
| topic | Biomedical and clinical sciences Medical biotechnology Pharmacology and pharmaceutical sciences chitooligosaccharides chitin chitosan anti-inflammatory antioxidant tissue engineering wound healing antimicrobial drug delivery antitumor |