Pharmacophore-based virtual screening approaches to identify novel molecular candidates against EGFR through comprehensive computational approaches and in-vitro studies

<div><p>Alterations to the EGFR (epidermal growth factor receptor) gene, which primarily occur in the axon 18–21 position, have been linked to a variety of cancers, including ovarian, breast, colon, and lung cancer. The use of TK inhibitors (gefitinib, erlotinib, lapatinib, and afatinib)...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: F A Dain Md Opo (14123109) (author)
مؤلفون آخرون: Mohammed Moulay (575948) (author), Ali Zari (12083666) (author), Afnan Alqaderi (14123112) (author), Saleh Alkarim (5914538) (author), Talal Zari (14123115) (author), Mohiuddin Ahmed Bhuiyan (9670038) (author), Maged Mostafa Mahmoud (14123118) (author), Fadwa Aljoud (14123121) (author), Mohd Suhail (528221) (author), Sherif Edris (521439) (author), Wafaa S. Ramadan (10538127) (author), Mohammad Amjad Kamal (9604771) (author), Saïd Nemmiche (14123124) (author), Foysal Ahammad (9286524) (author)
منشور في: 2022
الموضوعات:
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