Prevalence of polypharmacy and factors impacting psychotropic prescribing patterns in women of childbearing potential at inpatient mental health services in Qatar
<h3>Aims</h3><p dir="ltr">Women may experience unique mental disorders due to hormone shifts. Rates of schizophrenia and bipolar disorder are similar between genders, but onset and symptoms may differ. Women tend to use more psychotropic drugs due to limited therapeutic o...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , , , , , , , |
| منشور في: |
2024
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| الموضوعات: | |
| الوسوم: |
إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
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| _version_ | 1864513541471469568 |
|---|---|
| author | Nervana Elbakary (21480140) |
| author2 | Oraib Abdallah (12506762) Sami Ouanes (9617363) Ahmad Hasanoglu (22047332) Eiman Abedlfattah‐Arafa (22047335) Maha Al‐Shaikhly (22047338) Shatha Alqam (22047341) Sulaiman Alshakhs (22047344) Zainab Hijawi (21397925) Majid Al‐Abdulla (21632894) Noriya Al‐Khuzaei (22047347) Sazgar Hamad (22047350) |
| author2_role | author author author author author author author author author author author |
| author_facet | Nervana Elbakary (21480140) Oraib Abdallah (12506762) Sami Ouanes (9617363) Ahmad Hasanoglu (22047332) Eiman Abedlfattah‐Arafa (22047335) Maha Al‐Shaikhly (22047338) Shatha Alqam (22047341) Sulaiman Alshakhs (22047344) Zainab Hijawi (21397925) Majid Al‐Abdulla (21632894) Noriya Al‐Khuzaei (22047347) Sazgar Hamad (22047350) |
| author_role | author |
| dc.creator.none.fl_str_mv | Nervana Elbakary (21480140) Oraib Abdallah (12506762) Sami Ouanes (9617363) Ahmad Hasanoglu (22047332) Eiman Abedlfattah‐Arafa (22047335) Maha Al‐Shaikhly (22047338) Shatha Alqam (22047341) Sulaiman Alshakhs (22047344) Zainab Hijawi (21397925) Majid Al‐Abdulla (21632894) Noriya Al‐Khuzaei (22047347) Sazgar Hamad (22047350) |
| dc.date.none.fl_str_mv | 2024-08-20T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1002/npr2.12467 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Prevalence_of_polypharmacy_and_factors_impacting_psychotropic_prescribing_patterns_in_women_of_childbearing_potential_at_inpatient_mental_health_services_in_Qatar/29900282 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Pharmacology and pharmaceutical sciences Health sciences Health services and systems Human society Gender studies antipsychotics chlorpromazine hospital stay suicidal history treatment response |
| dc.title.none.fl_str_mv | Prevalence of polypharmacy and factors impacting psychotropic prescribing patterns in women of childbearing potential at inpatient mental health services in Qatar |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Aims</h3><p dir="ltr">Women may experience unique mental disorders due to hormone shifts. Rates of schizophrenia and bipolar disorder are similar between genders, but onset and symptoms may differ. Women tend to use more psychotropic drugs due to limited therapeutic options. This study was aimed to estimate the prevalence of psychotropic polypharmacy among females of childbearing potential and factors impacting prescribing patterns.</p><h3>Methods</h3><p dir="ltr">This was a quantitative retrospective chart review for patients admitted to inpatient units at the Mental Health Hospital in Qatar. SPSS® Statistics was used for data analysis. In addition to descriptive statistics applied, linear regression and binary logistic regression models were used to examine the clinical and sociodemographic factors associated with polypharmacy and full therapeutic response upon discharge, respectively. An alpha value of 0.05 was used.</p><h3>Results</h3><p dir="ltr">Of the 347 patients, 52.7% of the patients received a prescription of at least two psychotropic drugs upon discharge. Around two‐thirds (63.1%) were prescribed at least one antipsychotic. Potential predictors of polypharmacy were age (<i>p</i> = 0.027), longer hospital stay (<i>p</i> = 0.003), family history (<i>p</i> < 0.001), absence of suicidal history (<i>p</i> = 0.005), and a diagnosis of a mood disorder (<i>p</i> = 0.009), or a diagnosis of a psychotic disorder (<i>p</i> = 0.015). A full response upon discharge was less likely to occur in patients with a longer stay (OR = 0.940; <i>p</i> = 0.029) and in those with a substance use disorder (OR = 0.166; <i>p</i>= 0.035).</p><h3>Conclusion</h3><p dir="ltr">There is a notably high prevalence of total polypharmacy upon discharge. Some identified factors are modifiable. Evidence‐based prescription practices through hospital guidelines and education should be emphasized to avoid unreasonable polypharmacy.</p><h2>Other Information</h2><p dir="ltr">Published in: Neuropsychopharmacology Reports<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1002/npr2.12467" target="_blank">https://dx.doi.org/10.1002/npr2.12467</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_d3af0e18360321deda3123f0ff31eb2b |
| identifier_str_mv | 10.1002/npr2.12467 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/29900282 |
| publishDate | 2024 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Prevalence of polypharmacy and factors impacting psychotropic prescribing patterns in women of childbearing potential at inpatient mental health services in QatarNervana Elbakary (21480140)Oraib Abdallah (12506762)Sami Ouanes (9617363)Ahmad Hasanoglu (22047332)Eiman Abedlfattah‐Arafa (22047335)Maha Al‐Shaikhly (22047338)Shatha Alqam (22047341)Sulaiman Alshakhs (22047344)Zainab Hijawi (21397925)Majid Al‐Abdulla (21632894)Noriya Al‐Khuzaei (22047347)Sazgar Hamad (22047350)Biomedical and clinical sciencesClinical sciencesPharmacology and pharmaceutical sciencesHealth sciencesHealth services and systemsHuman societyGender studiesantipsychoticschlorpromazinehospital staysuicidal historytreatment response<h3>Aims</h3><p dir="ltr">Women may experience unique mental disorders due to hormone shifts. Rates of schizophrenia and bipolar disorder are similar between genders, but onset and symptoms may differ. Women tend to use more psychotropic drugs due to limited therapeutic options. This study was aimed to estimate the prevalence of psychotropic polypharmacy among females of childbearing potential and factors impacting prescribing patterns.</p><h3>Methods</h3><p dir="ltr">This was a quantitative retrospective chart review for patients admitted to inpatient units at the Mental Health Hospital in Qatar. SPSS® Statistics was used for data analysis. In addition to descriptive statistics applied, linear regression and binary logistic regression models were used to examine the clinical and sociodemographic factors associated with polypharmacy and full therapeutic response upon discharge, respectively. An alpha value of 0.05 was used.</p><h3>Results</h3><p dir="ltr">Of the 347 patients, 52.7% of the patients received a prescription of at least two psychotropic drugs upon discharge. Around two‐thirds (63.1%) were prescribed at least one antipsychotic. Potential predictors of polypharmacy were age (<i>p</i> = 0.027), longer hospital stay (<i>p</i> = 0.003), family history (<i>p</i> < 0.001), absence of suicidal history (<i>p</i> = 0.005), and a diagnosis of a mood disorder (<i>p</i> = 0.009), or a diagnosis of a psychotic disorder (<i>p</i> = 0.015). A full response upon discharge was less likely to occur in patients with a longer stay (OR = 0.940; <i>p</i> = 0.029) and in those with a substance use disorder (OR = 0.166; <i>p</i>= 0.035).</p><h3>Conclusion</h3><p dir="ltr">There is a notably high prevalence of total polypharmacy upon discharge. Some identified factors are modifiable. Evidence‐based prescription practices through hospital guidelines and education should be emphasized to avoid unreasonable polypharmacy.</p><h2>Other Information</h2><p dir="ltr">Published in: Neuropsychopharmacology Reports<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1002/npr2.12467" target="_blank">https://dx.doi.org/10.1002/npr2.12467</a></p>2024-08-20T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1002/npr2.12467https://figshare.com/articles/journal_contribution/Prevalence_of_polypharmacy_and_factors_impacting_psychotropic_prescribing_patterns_in_women_of_childbearing_potential_at_inpatient_mental_health_services_in_Qatar/29900282CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/299002822024-08-20T03:00:00Z |
| spellingShingle | Prevalence of polypharmacy and factors impacting psychotropic prescribing patterns in women of childbearing potential at inpatient mental health services in Qatar Nervana Elbakary (21480140) Biomedical and clinical sciences Clinical sciences Pharmacology and pharmaceutical sciences Health sciences Health services and systems Human society Gender studies antipsychotics chlorpromazine hospital stay suicidal history treatment response |
| status_str | publishedVersion |
| title | Prevalence of polypharmacy and factors impacting psychotropic prescribing patterns in women of childbearing potential at inpatient mental health services in Qatar |
| title_full | Prevalence of polypharmacy and factors impacting psychotropic prescribing patterns in women of childbearing potential at inpatient mental health services in Qatar |
| title_fullStr | Prevalence of polypharmacy and factors impacting psychotropic prescribing patterns in women of childbearing potential at inpatient mental health services in Qatar |
| title_full_unstemmed | Prevalence of polypharmacy and factors impacting psychotropic prescribing patterns in women of childbearing potential at inpatient mental health services in Qatar |
| title_short | Prevalence of polypharmacy and factors impacting psychotropic prescribing patterns in women of childbearing potential at inpatient mental health services in Qatar |
| title_sort | Prevalence of polypharmacy and factors impacting psychotropic prescribing patterns in women of childbearing potential at inpatient mental health services in Qatar |
| topic | Biomedical and clinical sciences Clinical sciences Pharmacology and pharmaceutical sciences Health sciences Health services and systems Human society Gender studies antipsychotics chlorpromazine hospital stay suicidal history treatment response |