Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential
<p dir="ltr">Lung cancer is one of the major causes of death worldwide. Natural molecules with anti-lung cancer potential are of a great interest and considered as very promising alternative to substitute or enhance the efficiency of the conventional drugs. Recently, algae as source...
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2020
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| _version_ | 1864513554528337920 |
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| author | Imen Saadaoui (14159025) |
| author2 | Rihab Rasheed (14153385) Nabeel Abdulrahman (725914) Touria Bounnit (16936899) Maroua Cherif (14153388) Hareb Al Jabri (14150487) Fatima Mraiche (715733) |
| author2_role | author author author author author author |
| author_facet | Imen Saadaoui (14159025) Rihab Rasheed (14153385) Nabeel Abdulrahman (725914) Touria Bounnit (16936899) Maroua Cherif (14153388) Hareb Al Jabri (14150487) Fatima Mraiche (715733) |
| author_role | author |
| dc.creator.none.fl_str_mv | Imen Saadaoui (14159025) Rihab Rasheed (14153385) Nabeel Abdulrahman (725914) Touria Bounnit (16936899) Maroua Cherif (14153388) Hareb Al Jabri (14150487) Fatima Mraiche (715733) |
| dc.date.none.fl_str_mv | 2020-04-08T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.3390/md18040197 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Algae-Derived_Bioactive_Compounds_with_Anti-Lung_Cancer_Potential/27896226 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Oncology and carcinogenesis Pharmacology and pharmaceutical sciences bioactives drug discovery marine algae mode of action molecular target lung cancer |
| dc.title.none.fl_str_mv | Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Lung cancer is one of the major causes of death worldwide. Natural molecules with anti-lung cancer potential are of a great interest and considered as very promising alternative to substitute or enhance the efficiency of the conventional drugs. Recently, algae as source of high value-added compounds are considered as very promising source of these bioactive molecules. These are secondary metabolites that consist mainly of derivatives of peptides, carbohydrates, and lipids with various structures. Accordingly, various mechanisms by which different algae molecules demonstrate attenuation of tumor angiogenesis were stated and discussed. The mode of action of the algae bioactives is closely related to their nature and chemical structure. Furthermore, this literature review considers the synergistic effect between microalgae bioactives and conventional drugs and discuss the economic feasibility of producing microalgae bioactives at large scale to conclude with some future perspectives related to algae-based drug discovery.</p><h2>Other Information</h2><p dir="ltr">Published in: Marine Drugs<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/md18040197" target="_blank">https://dx.doi.org/10.3390/md18040197</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_d4338bd971d4917509bc75b3cddf4bc3 |
| identifier_str_mv | 10.3390/md18040197 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/27896226 |
| publishDate | 2020 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Algae-Derived Bioactive Compounds with Anti-Lung Cancer PotentialImen Saadaoui (14159025)Rihab Rasheed (14153385)Nabeel Abdulrahman (725914)Touria Bounnit (16936899)Maroua Cherif (14153388)Hareb Al Jabri (14150487)Fatima Mraiche (715733)Biomedical and clinical sciencesOncology and carcinogenesisPharmacology and pharmaceutical sciencesbioactivesdrug discoverymarine algaemode of actionmolecular targetlung cancer<p dir="ltr">Lung cancer is one of the major causes of death worldwide. Natural molecules with anti-lung cancer potential are of a great interest and considered as very promising alternative to substitute or enhance the efficiency of the conventional drugs. Recently, algae as source of high value-added compounds are considered as very promising source of these bioactive molecules. These are secondary metabolites that consist mainly of derivatives of peptides, carbohydrates, and lipids with various structures. Accordingly, various mechanisms by which different algae molecules demonstrate attenuation of tumor angiogenesis were stated and discussed. The mode of action of the algae bioactives is closely related to their nature and chemical structure. Furthermore, this literature review considers the synergistic effect between microalgae bioactives and conventional drugs and discuss the economic feasibility of producing microalgae bioactives at large scale to conclude with some future perspectives related to algae-based drug discovery.</p><h2>Other Information</h2><p dir="ltr">Published in: Marine Drugs<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/md18040197" target="_blank">https://dx.doi.org/10.3390/md18040197</a></p>2020-04-08T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.3390/md18040197https://figshare.com/articles/journal_contribution/Algae-Derived_Bioactive_Compounds_with_Anti-Lung_Cancer_Potential/27896226CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/278962262020-04-08T03:00:00Z |
| spellingShingle | Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential Imen Saadaoui (14159025) Biomedical and clinical sciences Oncology and carcinogenesis Pharmacology and pharmaceutical sciences bioactives drug discovery marine algae mode of action molecular target lung cancer |
| status_str | publishedVersion |
| title | Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential |
| title_full | Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential |
| title_fullStr | Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential |
| title_full_unstemmed | Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential |
| title_short | Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential |
| title_sort | Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential |
| topic | Biomedical and clinical sciences Oncology and carcinogenesis Pharmacology and pharmaceutical sciences bioactives drug discovery marine algae mode of action molecular target lung cancer |