An overview of diabetes mellitus in pregnant women with obesity

<p>Rates of obesity are increasing world-wide with an estimated 1billion people projected to be obese by 2030 if current trends remain unchanged. Obesity currently considered one of the most significant associated factors of non-communicable diseases poses the greatest threat to health. Diabet...

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Main Author: Mohammed Bashir (5593550) (author)
Other Authors: Yassin Fagier (11304076) (author), Badreldeen Ahmed (21792905) (author), Justin C Konje (21792908) (author)
Published: 2024
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author Mohammed Bashir (5593550)
author2 Yassin Fagier (11304076)
Badreldeen Ahmed (21792905)
Justin C Konje (21792908)
author2_role author
author
author
author_facet Mohammed Bashir (5593550)
Yassin Fagier (11304076)
Badreldeen Ahmed (21792905)
Justin C Konje (21792908)
author_role author
dc.creator.none.fl_str_mv Mohammed Bashir (5593550)
Yassin Fagier (11304076)
Badreldeen Ahmed (21792905)
Justin C Konje (21792908)
dc.date.none.fl_str_mv 2024-02-15T15:00:00Z
dc.identifier.none.fl_str_mv 10.1016/j.bpobgyn.2024.102469
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/An_overview_of_diabetes_mellitus_in_pregnant_women_with_obesity/29651045
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Medical biochemistry and metabolomics
Reproductive medicine
Health sciences
Public health
Obesity
Diabetes in pregnancy
Type 2 diabetes mellitus
Gestational diabetes
Gestational weight gain
Metformin and insulin glucagon-like peptide 1
dc.title.none.fl_str_mv An overview of diabetes mellitus in pregnant women with obesity
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p>Rates of obesity are increasing world-wide with an estimated 1billion people projected to be obese by 2030 if current trends remain unchanged. Obesity currently considered one of the most significant associated factors of non-communicable diseases poses the greatest threat to health. Diabetes mellitus is an important metabolic disorder closely associated with obesity. It is therefore expected that with the increasing rates of obesity, the rates of diabetes in pregnancy will also be rising. This disorder may pre-date pregnancy (diagnosed or undiagnosed and diagnosed for the first time in pregnancy) or may be of onset in pregnancy. Irrespective of the timing of onset, diabetes in pregnancy is associated with both fetal and maternal complications. Outcomes are much better if control is maximised. Early diagnosis, multidisciplinary care and tailored management with optimum glycaemic control is associated with a significant reduction in not only pregnancy complications but long-term consequences on both the mother and offspring. This review brings together the current understanding of the pathogenesis of the endocrine derangements that are associated with diabetes in pregnancy how screening should be offered and management including pre-pregnancy care and the role of newer agents in management.</p><h2>Other Information</h2> <p> Published in: Best Practice & Research Clinical Obstetrics & Gynaecology<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.bpobgyn.2024.102469" target="_blank">https://dx.doi.org/10.1016/j.bpobgyn.2024.102469</a></p>
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identifier_str_mv 10.1016/j.bpobgyn.2024.102469
network_acronym_str Manara2
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oai_identifier_str oai:figshare.com:article/29651045
publishDate 2024
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spelling An overview of diabetes mellitus in pregnant women with obesityMohammed Bashir (5593550)Yassin Fagier (11304076)Badreldeen Ahmed (21792905)Justin C Konje (21792908)Biomedical and clinical sciencesMedical biochemistry and metabolomicsReproductive medicineHealth sciencesPublic healthObesityDiabetes in pregnancyType 2 diabetes mellitusGestational diabetesGestational weight gainMetformin and insulin glucagon-like peptide 1<p>Rates of obesity are increasing world-wide with an estimated 1billion people projected to be obese by 2030 if current trends remain unchanged. Obesity currently considered one of the most significant associated factors of non-communicable diseases poses the greatest threat to health. Diabetes mellitus is an important metabolic disorder closely associated with obesity. It is therefore expected that with the increasing rates of obesity, the rates of diabetes in pregnancy will also be rising. This disorder may pre-date pregnancy (diagnosed or undiagnosed and diagnosed for the first time in pregnancy) or may be of onset in pregnancy. Irrespective of the timing of onset, diabetes in pregnancy is associated with both fetal and maternal complications. Outcomes are much better if control is maximised. Early diagnosis, multidisciplinary care and tailored management with optimum glycaemic control is associated with a significant reduction in not only pregnancy complications but long-term consequences on both the mother and offspring. This review brings together the current understanding of the pathogenesis of the endocrine derangements that are associated with diabetes in pregnancy how screening should be offered and management including pre-pregnancy care and the role of newer agents in management.</p><h2>Other Information</h2> <p> Published in: Best Practice & Research Clinical Obstetrics & Gynaecology<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.bpobgyn.2024.102469" target="_blank">https://dx.doi.org/10.1016/j.bpobgyn.2024.102469</a></p>2024-02-15T15:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.bpobgyn.2024.102469https://figshare.com/articles/journal_contribution/An_overview_of_diabetes_mellitus_in_pregnant_women_with_obesity/29651045CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/296510452024-02-15T15:00:00Z
spellingShingle An overview of diabetes mellitus in pregnant women with obesity
Mohammed Bashir (5593550)
Biomedical and clinical sciences
Medical biochemistry and metabolomics
Reproductive medicine
Health sciences
Public health
Obesity
Diabetes in pregnancy
Type 2 diabetes mellitus
Gestational diabetes
Gestational weight gain
Metformin and insulin glucagon-like peptide 1
status_str publishedVersion
title An overview of diabetes mellitus in pregnant women with obesity
title_full An overview of diabetes mellitus in pregnant women with obesity
title_fullStr An overview of diabetes mellitus in pregnant women with obesity
title_full_unstemmed An overview of diabetes mellitus in pregnant women with obesity
title_short An overview of diabetes mellitus in pregnant women with obesity
title_sort An overview of diabetes mellitus in pregnant women with obesity
topic Biomedical and clinical sciences
Medical biochemistry and metabolomics
Reproductive medicine
Health sciences
Public health
Obesity
Diabetes in pregnancy
Type 2 diabetes mellitus
Gestational diabetes
Gestational weight gain
Metformin and insulin glucagon-like peptide 1