Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis
<h3>Background</h3><p dir="ltr">The increasing prevalence of diabetic ketoacidosis (DKA) related admissions poses a significant burden on the healthcare systems globally. However, data regarding the predictors of healthcare resource utilization in DKA is limited and incon...
محفوظ في:
| المؤلف الرئيسي: | |
|---|---|
| مؤلفون آخرون: | , , , , , , , , , , , |
| منشور في: |
2023
|
| الموضوعات: | |
| الوسوم: |
إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
|
| _version_ | 1864513528287723520 |
|---|---|
| author | Fateen Ata (12217764) |
| author2 | Adeel Ahmad Khan (14152953) Ibrahim Khamees (14153301) Phool Iqbal (12217770) Zohaib Yousaf (9617058) Bayan Z. M. Mohammed (14572840) Reham Aboshdid (14572843) Sandy K. K. Marzouk (14572846) Haidar Barjas (14572849) Madiha Khalid (10196725) Ihab El Madhoun (14151594) Mohammed Bashir (5593550) Anand Kartha (9658520) |
| author2_role | author author author author author author author author author author author author |
| author_facet | Fateen Ata (12217764) Adeel Ahmad Khan (14152953) Ibrahim Khamees (14153301) Phool Iqbal (12217770) Zohaib Yousaf (9617058) Bayan Z. M. Mohammed (14572840) Reham Aboshdid (14572843) Sandy K. K. Marzouk (14572846) Haidar Barjas (14572849) Madiha Khalid (10196725) Ihab El Madhoun (14151594) Mohammed Bashir (5593550) Anand Kartha (9658520) |
| author_role | author |
| dc.creator.none.fl_str_mv | Fateen Ata (12217764) Adeel Ahmad Khan (14152953) Ibrahim Khamees (14153301) Phool Iqbal (12217770) Zohaib Yousaf (9617058) Bayan Z. M. Mohammed (14572840) Reham Aboshdid (14572843) Sandy K. K. Marzouk (14572846) Haidar Barjas (14572849) Madiha Khalid (10196725) Ihab El Madhoun (14151594) Mohammed Bashir (5593550) Anand Kartha (9658520) |
| dc.date.none.fl_str_mv | 2023-02-06T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1080/07853890.2023.2175031 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Clinical_and_biochemical_determinants_of_length_of_stay_readmission_and_recurrence_in_patients_admitted_with_diabetic_ketoacidosis/25150958 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Nutrition and dietetics Diabetic ketoacidosis DKA type 1 diabetes type 2 diabetes length of stay recurrence readmission |
| dc.title.none.fl_str_mv | Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Background</h3><p dir="ltr">The increasing prevalence of diabetic ketoacidosis (DKA) related admissions poses a significant burden on the healthcare systems globally. However, data regarding the predictors of healthcare resource utilization in DKA is limited and inconsistent. This study aimed to identify key predictors of hospital length of stay (LOS), readmission and recurrent DKA episodes.</p><h3>Methods</h3><p dir="ltr">We undertook a retrospective cross-sectional analysis of all DKA admissions from 2015 to 2021 across four hospitals in Qatar. The primary outcomes were the length of stay (LOS), 90-day readmission and 6-month and 1-year DKA recurrence.</p><h3>Results</h3><p dir="ltr">We included 922 patients with a median age of 35 years (25–45). 62% were males with type-1 diabetes-mellitus (T1DM) and type-2 DM (T2DM), present in 52% and 48% of patients. The median LOS was 2.6 days (IQR 1.1–4.8), and the median DKA resolution time was 18 h (10.5–29). Male-gender, new-onset DM, higher Charlson Comorbidity Index (CCI), lower haemoglobin, sodium and potassium, higher urea, longer DKA duration and MICU admission predicted a longer LOS in a multivariate regression analysis. None of the factors were significantly associated with 90-day readmission. Patients with pre-existing T1DM were more likely to have a six-month DKA recurrence than pre-existing T2DM. Patients with a 6-month DKA recurrence, female gender and T1DM had higher odds of 12-month recurrence, whereas a consult with a diabetes educator at the index admission was associated with decreased odds of recurrence.</p><h3>Conclusions/interpretation</h3><p dir="ltr">This is the most extensive study from the Middle-East region reporting on LOS, readmissions and the recurrence of DKA. Results from this study with a diverse population may be valuable for physicians and healthcare systems to decrease the diabetes-related healthcare burden in DKA patients.</p><h2>Other Information</h2><p dir="ltr">Published in: Annals of Medicine<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1080/07853890.2023.2175031" target="_blank">https://dx.doi.org/10.1080/07853890.2023.2175031</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_d70ac473e50c52d607faf630d0ce9953 |
| identifier_str_mv | 10.1080/07853890.2023.2175031 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/25150958 |
| publishDate | 2023 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosisFateen Ata (12217764)Adeel Ahmad Khan (14152953)Ibrahim Khamees (14153301)Phool Iqbal (12217770)Zohaib Yousaf (9617058)Bayan Z. M. Mohammed (14572840)Reham Aboshdid (14572843)Sandy K. K. Marzouk (14572846)Haidar Barjas (14572849)Madiha Khalid (10196725)Ihab El Madhoun (14151594)Mohammed Bashir (5593550)Anand Kartha (9658520)Biomedical and clinical sciencesClinical sciencesNutrition and dieteticsDiabetic ketoacidosisDKAtype 1 diabetestype 2 diabeteslength of stayrecurrencereadmission<h3>Background</h3><p dir="ltr">The increasing prevalence of diabetic ketoacidosis (DKA) related admissions poses a significant burden on the healthcare systems globally. However, data regarding the predictors of healthcare resource utilization in DKA is limited and inconsistent. This study aimed to identify key predictors of hospital length of stay (LOS), readmission and recurrent DKA episodes.</p><h3>Methods</h3><p dir="ltr">We undertook a retrospective cross-sectional analysis of all DKA admissions from 2015 to 2021 across four hospitals in Qatar. The primary outcomes were the length of stay (LOS), 90-day readmission and 6-month and 1-year DKA recurrence.</p><h3>Results</h3><p dir="ltr">We included 922 patients with a median age of 35 years (25–45). 62% were males with type-1 diabetes-mellitus (T1DM) and type-2 DM (T2DM), present in 52% and 48% of patients. The median LOS was 2.6 days (IQR 1.1–4.8), and the median DKA resolution time was 18 h (10.5–29). Male-gender, new-onset DM, higher Charlson Comorbidity Index (CCI), lower haemoglobin, sodium and potassium, higher urea, longer DKA duration and MICU admission predicted a longer LOS in a multivariate regression analysis. None of the factors were significantly associated with 90-day readmission. Patients with pre-existing T1DM were more likely to have a six-month DKA recurrence than pre-existing T2DM. Patients with a 6-month DKA recurrence, female gender and T1DM had higher odds of 12-month recurrence, whereas a consult with a diabetes educator at the index admission was associated with decreased odds of recurrence.</p><h3>Conclusions/interpretation</h3><p dir="ltr">This is the most extensive study from the Middle-East region reporting on LOS, readmissions and the recurrence of DKA. Results from this study with a diverse population may be valuable for physicians and healthcare systems to decrease the diabetes-related healthcare burden in DKA patients.</p><h2>Other Information</h2><p dir="ltr">Published in: Annals of Medicine<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1080/07853890.2023.2175031" target="_blank">https://dx.doi.org/10.1080/07853890.2023.2175031</a></p>2023-02-06T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1080/07853890.2023.2175031https://figshare.com/articles/journal_contribution/Clinical_and_biochemical_determinants_of_length_of_stay_readmission_and_recurrence_in_patients_admitted_with_diabetic_ketoacidosis/25150958CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/251509582023-02-06T03:00:00Z |
| spellingShingle | Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis Fateen Ata (12217764) Biomedical and clinical sciences Clinical sciences Nutrition and dietetics Diabetic ketoacidosis DKA type 1 diabetes type 2 diabetes length of stay recurrence readmission |
| status_str | publishedVersion |
| title | Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis |
| title_full | Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis |
| title_fullStr | Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis |
| title_full_unstemmed | Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis |
| title_short | Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis |
| title_sort | Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis |
| topic | Biomedical and clinical sciences Clinical sciences Nutrition and dietetics Diabetic ketoacidosis DKA type 1 diabetes type 2 diabetes length of stay recurrence readmission |