Neuroreceptor Activation by Vibration-Assisted Tunneling

Neuroreceptor Activation by Vibration-Assisted Tunneling

<p dir="ltr">G protein-coupled receptors (GPCRs) constitute a large family of receptor proteinsthat sense molecular signals on the exterior of a cell and activate signaltransduction pathways within the cell. Modeling how an agonist activates such areceptor is fundamental for an under...

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Bibliographic Details
Main Author: Ross D. Hoehn (1836382) (author)
Other Authors: David Nichols (3527624) (author), Hartmut Neven (19651873) (author), Sabre Kais (1409968) (author)
Published: 2015
Subjects:
Biomedical and clinical sciences
Medical biochemistry and metabolomics
Medical physiology
Neurosciences
Pharmacology and pharmaceutical sciences
Information and computing sciences
Theory of computation
Biophysical chemistry
Mechanism of action
Drug design
Serotonin receptor
Deuterated isotopologues
Neurobiology
Quantum chemical modeling
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