Patient with clinical celiac disease mimicking triple‐negative essential thrombocythemia
<p>Platelets are acute-phase reactants, which can be elevated due to a secondary cause or less commonly because of a primary mechanism. Primary disorders include hematological conditions such as myelodysplastic syndrome, acute myeloid leukemia, chronic myeloid leukemia, polycythemia vera, and...
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2023
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| _version_ | 1864513565686235136 |
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| author | Elrazi A. Ali (14777365) |
| author2 | Kamran Mushtaq (14150814) Elabbass Abdelmahmuod (14777287) Mohamed A. Yassin (8361183) |
| author2_role | author author author |
| author_facet | Elrazi A. Ali (14777365) Kamran Mushtaq (14150814) Elabbass Abdelmahmuod (14777287) Mohamed A. Yassin (8361183) |
| author_role | author |
| dc.creator.none.fl_str_mv | Elrazi A. Ali (14777365) Kamran Mushtaq (14150814) Elabbass Abdelmahmuod (14777287) Mohamed A. Yassin (8361183) |
| dc.date.none.fl_str_mv | 2023-03-16T06:21:05Z |
| dc.identifier.none.fl_str_mv | 10.1002/ccr3.5197 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Patient_with_clinical_celiac_disease_mimicking_triple_negative_essential_thrombocythemia/22257874 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences General Medicine |
| dc.title.none.fl_str_mv | Patient with clinical celiac disease mimicking triple‐negative essential thrombocythemia |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p>Platelets are acute-phase reactants, which can be elevated due to a secondary cause or less commonly because of a primary mechanism. Primary disorders include hematological conditions such as myelodysplastic syndrome, acute myeloid leukemia, chronic myeloid leukemia, polycythemia vera, and essential thrombocythemia (ET). Most ET patients have a mutation in the genes regulating thrombopoiesis, <em>JAK2</em>, <em>CALR</em>, or <em>MPL</em> genes. But 10%–15% of ET patients are triple-negative, where patients have no detectable mutation. We report a young patient with no significant past medical history evaluated for persistent thrombocytosis. She was initially diagnosed as triple-negative ET based on a bone marrow biopsy. She had positive antibodies for celiac disease, and the diagnosis was confirmed by a small bowel biopsy, which is confirmatory for diagnosing celiac disease in adults. We recommend screening triple-negative ET patients for celiac disease before going to more expensive tests. </p> <h2>Other Information</h2> <p>Published in: Clinical Case Reports<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br> See article on publisher's website: <a href="http://dx.doi.org/10.1002/ccr3.5197" target="_blank">http://dx.doi.org/10.1002/ccr3.5197</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_d9ba3892f07ef6de1b01d91175b7ae8a |
| identifier_str_mv | 10.1002/ccr3.5197 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/22257874 |
| publishDate | 2023 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Patient with clinical celiac disease mimicking triple‐negative essential thrombocythemiaElrazi A. Ali (14777365)Kamran Mushtaq (14150814)Elabbass Abdelmahmuod (14777287)Mohamed A. Yassin (8361183)Biomedical and clinical sciencesClinical sciencesGeneral Medicine<p>Platelets are acute-phase reactants, which can be elevated due to a secondary cause or less commonly because of a primary mechanism. Primary disorders include hematological conditions such as myelodysplastic syndrome, acute myeloid leukemia, chronic myeloid leukemia, polycythemia vera, and essential thrombocythemia (ET). Most ET patients have a mutation in the genes regulating thrombopoiesis, <em>JAK2</em>, <em>CALR</em>, or <em>MPL</em> genes. But 10%–15% of ET patients are triple-negative, where patients have no detectable mutation. We report a young patient with no significant past medical history evaluated for persistent thrombocytosis. She was initially diagnosed as triple-negative ET based on a bone marrow biopsy. She had positive antibodies for celiac disease, and the diagnosis was confirmed by a small bowel biopsy, which is confirmatory for diagnosing celiac disease in adults. We recommend screening triple-negative ET patients for celiac disease before going to more expensive tests. </p> <h2>Other Information</h2> <p>Published in: Clinical Case Reports<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br> See article on publisher's website: <a href="http://dx.doi.org/10.1002/ccr3.5197" target="_blank">http://dx.doi.org/10.1002/ccr3.5197</a></p>2023-03-16T06:21:05ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1002/ccr3.5197https://figshare.com/articles/journal_contribution/Patient_with_clinical_celiac_disease_mimicking_triple_negative_essential_thrombocythemia/22257874CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/222578742023-03-16T06:21:05Z |
| spellingShingle | Patient with clinical celiac disease mimicking triple‐negative essential thrombocythemia Elrazi A. Ali (14777365) Biomedical and clinical sciences Clinical sciences General Medicine |
| status_str | publishedVersion |
| title | Patient with clinical celiac disease mimicking triple‐negative essential thrombocythemia |
| title_full | Patient with clinical celiac disease mimicking triple‐negative essential thrombocythemia |
| title_fullStr | Patient with clinical celiac disease mimicking triple‐negative essential thrombocythemia |
| title_full_unstemmed | Patient with clinical celiac disease mimicking triple‐negative essential thrombocythemia |
| title_short | Patient with clinical celiac disease mimicking triple‐negative essential thrombocythemia |
| title_sort | Patient with clinical celiac disease mimicking triple‐negative essential thrombocythemia |
| topic | Biomedical and clinical sciences Clinical sciences General Medicine |