Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin

<p></p><div> <p>Lamotrigine has been repeatedly reported to cause hematologic toxicities, which may be associated with high initial doses or excessive escalation. A 29-year-old lady experienced profound neutropenia after two weeks of lamotrigine high initial dose, started wit...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Muhammad Salem (8979428) (author)
مؤلفون آخرون: Ahmed El‐Bardissy (14777851) (author)
منشور في: 2023
الموضوعات:
الوسوم: إضافة وسم
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الوصف
الملخص:<p></p><div> <p>Lamotrigine has been repeatedly reported to cause hematologic toxicities, which may be associated with high initial doses or excessive escalation. A 29-year-old lady experienced profound neutropenia after two weeks of lamotrigine high initial dose, started within two days of phenytoin. The too-early dose intensification may have produced lamotrigine-induced blood dyscrasia.</p> </div><p></p><h2>Other Information</h2> <p> Published in: Clinical Case Reports<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1002/ccr3.5136" target="_blank">http://dx.doi.org/10.1002/ccr3.5136</a></p>