Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin
<p></p><div> <p>Lamotrigine has been repeatedly reported to cause hematologic toxicities, which may be associated with high initial doses or excessive escalation. A 29-year-old lady experienced profound neutropenia after two weeks of lamotrigine high initial dose, started wit...
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2023
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| _version_ | 1864513565692526592 |
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| author | Muhammad Salem (8979428) |
| author2 | Ahmed El‐Bardissy (14777851) |
| author2_role | author |
| author_facet | Muhammad Salem (8979428) Ahmed El‐Bardissy (14777851) |
| author_role | author |
| dc.creator.none.fl_str_mv | Muhammad Salem (8979428) Ahmed El‐Bardissy (14777851) |
| dc.date.none.fl_str_mv | 2023-03-16T06:20:57Z |
| dc.identifier.none.fl_str_mv | 10.1002/ccr3.5136 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Lamotrigine_induced_neutropenia_after_high_dose_concomitant_initiation_with_phenytoin/22257853 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences General Medicine |
| dc.title.none.fl_str_mv | Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p></p><div> <p>Lamotrigine has been repeatedly reported to cause hematologic toxicities, which may be associated with high initial doses or excessive escalation. A 29-year-old lady experienced profound neutropenia after two weeks of lamotrigine high initial dose, started within two days of phenytoin. The too-early dose intensification may have produced lamotrigine-induced blood dyscrasia.</p> </div><p></p><h2>Other Information</h2> <p> Published in: Clinical Case Reports<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1002/ccr3.5136" target="_blank">http://dx.doi.org/10.1002/ccr3.5136</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_db519566758e2b2fe7d8862e844184d6 |
| identifier_str_mv | 10.1002/ccr3.5136 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/22257853 |
| publishDate | 2023 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoinMuhammad Salem (8979428)Ahmed El‐Bardissy (14777851)Biomedical and clinical sciencesClinical sciencesGeneral Medicine<p></p><div> <p>Lamotrigine has been repeatedly reported to cause hematologic toxicities, which may be associated with high initial doses or excessive escalation. A 29-year-old lady experienced profound neutropenia after two weeks of lamotrigine high initial dose, started within two days of phenytoin. The too-early dose intensification may have produced lamotrigine-induced blood dyscrasia.</p> </div><p></p><h2>Other Information</h2> <p> Published in: Clinical Case Reports<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1002/ccr3.5136" target="_blank">http://dx.doi.org/10.1002/ccr3.5136</a></p>2023-03-16T06:20:57ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1002/ccr3.5136https://figshare.com/articles/journal_contribution/Lamotrigine_induced_neutropenia_after_high_dose_concomitant_initiation_with_phenytoin/22257853CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/222578532023-03-16T06:20:57Z |
| spellingShingle | Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin Muhammad Salem (8979428) Biomedical and clinical sciences Clinical sciences General Medicine |
| status_str | publishedVersion |
| title | Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin |
| title_full | Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin |
| title_fullStr | Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin |
| title_full_unstemmed | Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin |
| title_short | Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin |
| title_sort | Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin |
| topic | Biomedical and clinical sciences Clinical sciences General Medicine |