Prediction of in-hospital mortality in patients with post traumatic brain injury using National Trauma Registry and Machine Learning Approach

<h3>Background</h3><p dir="ltr">The use of machine learning techniques to predict diseases outcomes has grown significantly in the last decade. Several studies prove that the machine learning predictive techniques outperform the classical multivariate techniques. We aimed...

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Main Author: Ahmad Abujaber (9100064) (author)
Other Authors: Adam Fadlalla (9100067) (author), Diala Gammoh (9100070) (author), Husham Abdelrahman (768893) (author), Monira Mollazehi (9100073) (author), Ayman El-Menyar (440103) (author)
Published: 2022
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_version_ 1864513566573330432
author Ahmad Abujaber (9100064)
author2 Adam Fadlalla (9100067)
Diala Gammoh (9100070)
Husham Abdelrahman (768893)
Monira Mollazehi (9100073)
Ayman El-Menyar (440103)
author2_role author
author
author
author
author
author_facet Ahmad Abujaber (9100064)
Adam Fadlalla (9100067)
Diala Gammoh (9100070)
Husham Abdelrahman (768893)
Monira Mollazehi (9100073)
Ayman El-Menyar (440103)
author_role author
dc.creator.none.fl_str_mv Ahmad Abujaber (9100064)
Adam Fadlalla (9100067)
Diala Gammoh (9100070)
Husham Abdelrahman (768893)
Monira Mollazehi (9100073)
Ayman El-Menyar (440103)
dc.date.none.fl_str_mv 2022-11-22T21:18:14Z
dc.identifier.none.fl_str_mv 10.1186/s13049-020-00738-5
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Prediction_of_in-hospital_mortality_in_patients_with_post_traumatic_brain_injury_using_National_Trauma_Registry_and_Machine_Learning_Approach/21598473
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Clinical sciences
Engineering
Biomedical engineering
Information and computing sciences
Artificial intelligence
Prediction models
Traumatic brain injury
Machine learning approach
dc.title.none.fl_str_mv Prediction of in-hospital mortality in patients with post traumatic brain injury using National Trauma Registry and Machine Learning Approach
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3>Background</h3><p dir="ltr">The use of machine learning techniques to predict diseases outcomes has grown significantly in the last decade. Several studies prove that the machine learning predictive techniques outperform the classical multivariate techniques. We aimed to build a machine learning predictive model to predict the in-hospital mortality for patients who sustained Traumatic Brain Injury (TBI).</p><h3>Methods</h3><p dir="ltr">Adult patients with TBI who were hospitalized in the level 1 trauma center in the period from January 2014 to February 2019 were included in this study. Patients’ demographics, injury characteristics and CT findings were used as predictors. The predictive performance of Artificial Neural Networks (ANN) and Support Vector Machines (SVM) was evaluated in terms of accuracy, Area Under the Curve (AUC), sensitivity, precision, Negative Predictive Value (NPV), specificity and F-score.</p><h3>Results</h3><p dir="ltr">A total of 1620 eligible patients were included in the study (1417 survival and 203 non-survivals). Both models achieved accuracy over 91% and AUC over 93%. SVM achieved the optimal performance with accuracy 95.6% and AUC 96%.</p><h3>Conclusions</h3><p dir="ltr">for prediction of mortality in patients with TBI, SVM outperformed the well-known classical models that utilized the conventional multivariate analytical techniques.</p><h2>Other Information</h2><p dir="ltr">Published in: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1186/s13049-020-00738-5" target="_blank">http://dx.doi.org/10.1186/s13049-020-00738-5</a></p>
eu_rights_str_mv openAccess
id Manara2_dda611ede21c617e3f8b8b07c17fc381
identifier_str_mv 10.1186/s13049-020-00738-5
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/21598473
publishDate 2022
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY 4.0
spelling Prediction of in-hospital mortality in patients with post traumatic brain injury using National Trauma Registry and Machine Learning ApproachAhmad Abujaber (9100064)Adam Fadlalla (9100067)Diala Gammoh (9100070)Husham Abdelrahman (768893)Monira Mollazehi (9100073)Ayman El-Menyar (440103)Biomedical and clinical sciencesClinical sciencesEngineeringBiomedical engineeringInformation and computing sciencesArtificial intelligencePrediction modelsTraumatic brain injuryMachine learning approach<h3>Background</h3><p dir="ltr">The use of machine learning techniques to predict diseases outcomes has grown significantly in the last decade. Several studies prove that the machine learning predictive techniques outperform the classical multivariate techniques. We aimed to build a machine learning predictive model to predict the in-hospital mortality for patients who sustained Traumatic Brain Injury (TBI).</p><h3>Methods</h3><p dir="ltr">Adult patients with TBI who were hospitalized in the level 1 trauma center in the period from January 2014 to February 2019 were included in this study. Patients’ demographics, injury characteristics and CT findings were used as predictors. The predictive performance of Artificial Neural Networks (ANN) and Support Vector Machines (SVM) was evaluated in terms of accuracy, Area Under the Curve (AUC), sensitivity, precision, Negative Predictive Value (NPV), specificity and F-score.</p><h3>Results</h3><p dir="ltr">A total of 1620 eligible patients were included in the study (1417 survival and 203 non-survivals). Both models achieved accuracy over 91% and AUC over 93%. SVM achieved the optimal performance with accuracy 95.6% and AUC 96%.</p><h3>Conclusions</h3><p dir="ltr">for prediction of mortality in patients with TBI, SVM outperformed the well-known classical models that utilized the conventional multivariate analytical techniques.</p><h2>Other Information</h2><p dir="ltr">Published in: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1186/s13049-020-00738-5" target="_blank">http://dx.doi.org/10.1186/s13049-020-00738-5</a></p>2022-11-22T21:18:14ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1186/s13049-020-00738-5https://figshare.com/articles/journal_contribution/Prediction_of_in-hospital_mortality_in_patients_with_post_traumatic_brain_injury_using_National_Trauma_Registry_and_Machine_Learning_Approach/21598473CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/215984732022-11-22T21:18:14Z
spellingShingle Prediction of in-hospital mortality in patients with post traumatic brain injury using National Trauma Registry and Machine Learning Approach
Ahmad Abujaber (9100064)
Biomedical and clinical sciences
Clinical sciences
Engineering
Biomedical engineering
Information and computing sciences
Artificial intelligence
Prediction models
Traumatic brain injury
Machine learning approach
status_str publishedVersion
title Prediction of in-hospital mortality in patients with post traumatic brain injury using National Trauma Registry and Machine Learning Approach
title_full Prediction of in-hospital mortality in patients with post traumatic brain injury using National Trauma Registry and Machine Learning Approach
title_fullStr Prediction of in-hospital mortality in patients with post traumatic brain injury using National Trauma Registry and Machine Learning Approach
title_full_unstemmed Prediction of in-hospital mortality in patients with post traumatic brain injury using National Trauma Registry and Machine Learning Approach
title_short Prediction of in-hospital mortality in patients with post traumatic brain injury using National Trauma Registry and Machine Learning Approach
title_sort Prediction of in-hospital mortality in patients with post traumatic brain injury using National Trauma Registry and Machine Learning Approach
topic Biomedical and clinical sciences
Clinical sciences
Engineering
Biomedical engineering
Information and computing sciences
Artificial intelligence
Prediction models
Traumatic brain injury
Machine learning approach