Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy

Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy

<div><p>Esophageal cancer (EC) is a disease often marked by aggressive growth and poor prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant metastases among patients with advanced disease account for the high mortality rate. The tumor microenvironment...

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Main Author: Ajaz A. Bhat (12984701) (author)
Other Authors: Sabah Nisar (12561961) (author), Selma Maacha (501715) (author), Tatiana Correa Carneiro-Lobo (18459033) (author), Sabah Akhtar (5809925) (author), Kodappully Sivaraman Siveen (9440771) (author), Nissar A. Wani (15070399) (author), Arshi Rizwan (18278773) (author), Puneet Bagga (4055866) (author), Mayank Singh (793077) (author), Ravinder Reddy (564813) (author), Shahab Uddin (154400) (author), Jean-Charles Grivel (284645) (author), Gyan Chand (452737) (author), Michael P. Frenneaux (9538623) (author), Mushtaq A. Siddiqi (18459036) (author), Davide Bedognetti (2632474) (author), Wael El-Rifai (303374) (author), Muzafar A. Macha (11605200) (author), Mohammad Haris (564809) (author)
Published: 2021
Subjects:
Biomedical and clinical sciences
Immunology
Oncology and carcinogenesis
Esophageal cancer
Cytokines
Chemokines
Inflammation
Tumor microenvironment
Epithelial-Mesenchymal transition
Drug targets
Immune evasion
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