Transcriptomic Profiling of Tumor-Infiltrating CD4<sup>+</sup>TIM-3<sup>+</sup> T Cells Reveals Their Suppressive, Exhausted, and Metastatic Characteristics in Colorectal Cancer Patients
<p dir="ltr">T cell immunoglobulin mucin-3 (TIM-3) is an immune checkpoint identified as one of the key players in regulating T-cell responses. Studies have shown that TIM-3 is upregulated in the tumor microenvironment (TME). However, the precise role of TIM-3 in colorectal cancer (C...
محفوظ في:
| المؤلف الرئيسي: | Varun Sasidharan Nair (5396393) (author) |
|---|---|
| مؤلفون آخرون: | Salman M Toor (18623267) (author), Rowaida Z Taha (18719002) (author), Ayman A Ahmed (18719005) (author), Mohamed A Kurer (18719008) (author), Khaled Murshed (8309781) (author), Madiha E Soofi (18719011) (author), Khalid Ouararhni (3145734) (author), Nehad M. Alajez (18197) (author), Mohamed Abu Nada (8309784) (author), Eyad Elkord (5396390) (author) |
| منشور في: |
2020
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| الموضوعات: | |
| الوسوم: |
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مواد مشابهة
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