Extensive Foreign Body Reaction to Synthetic Dural Replacement After Decompressive Craniectomy with Radiological and Histopathology Evidence: Observational Case Series
<h3>Background</h3><p dir="ltr">Though the indications are quite varied, decompressive craniectomy is considered a life-saving procedure. Maximal effectiveness of craniectomy is achieved when, in addition to bone removal, the dura mater is opened properly and is augmented...
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| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , , , |
| منشور في: |
2023
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| الموضوعات: | |
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| _version_ | 1864513528403066880 |
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| author | Kazim Mohammed (17884289) |
| author2 | Javeed Iqbal (5514728) Mohsin Arshad (17884292) Ala Saleem Abu-Dayeh (17884295) Issam Albozom (17545668) Abdulnasser Alyafei (17542458) Tarek ben Zabih (17884298) Sirajeddin Belkhair (17151106) |
| author2_role | author author author author author author author |
| author_facet | Kazim Mohammed (17884289) Javeed Iqbal (5514728) Mohsin Arshad (17884292) Ala Saleem Abu-Dayeh (17884295) Issam Albozom (17545668) Abdulnasser Alyafei (17542458) Tarek ben Zabih (17884298) Sirajeddin Belkhair (17151106) |
| author_role | author |
| dc.creator.none.fl_str_mv | Kazim Mohammed (17884289) Javeed Iqbal (5514728) Mohsin Arshad (17884292) Ala Saleem Abu-Dayeh (17884295) Issam Albozom (17545668) Abdulnasser Alyafei (17542458) Tarek ben Zabih (17884298) Sirajeddin Belkhair (17151106) |
| dc.date.none.fl_str_mv | 2023-04-01T00:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1016/j.wneu.2023.01.089 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Extensive_Foreign_Body_Reaction_to_Synthetic_Dural_Replacement_After_Decompressive_Craniectomy_with_Radiological_and_Histopathology_Evidence_Observational_Case_Series/25124396 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Neurosciences Cerebrospinal fluid leak Craniectomy Cranioplasty CSF Duraplasty Extensive foreign body reaction Granulomatous reaction Synthetic dural materials |
| dc.title.none.fl_str_mv | Extensive Foreign Body Reaction to Synthetic Dural Replacement After Decompressive Craniectomy with Radiological and Histopathology Evidence: Observational Case Series |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Background</h3><p dir="ltr">Though the indications are quite varied, decompressive craniectomy is considered a life-saving procedure. Maximal effectiveness of craniectomy is achieved when, in addition to bone removal, the dura mater is opened properly and is augmented with duraplasty. Different synthetic materials have been used over the decades to replace the dura during decompressive craniectomy. We have used different synthetic dural replacements at our institution, including Neuro-Patch, DuraGen, and Lyoplant. In this case series, we described 4 cases that had excessive granulation tissue formation in response to a newly used synthetic dural substitute (ReDura) after emergent decompressive craniectomy. During follow-up brain imaging at different intervals, these cases were found to have foreign body reaction in the form of excessive granulation tissue formation; additionally, 1 case had a sterile pus-like collection. The granulation tissue diagnosis was affirmed by histopathology in all 4 cases.</p><p><br></p><h3>Methods</h3><p dir="ltr">This study was an observational retrograde case series, with data obtained from electronic medical records.</p><p><br></p><h3>Results</h3><p dir="ltr">The study showed extensive foreign body giant cell reactions on preoperative computed tomography scans, indicating a very high occurrence rate of 72.4%, when ReDura was used as dural replacement.</p><p><br></p><h3>Conclusions</h3><p dir="ltr">Our experience showed that patients are prone to develop severe foreign body giant cell reactions with ReDura. Neurosurgical centers using this material should monitor patients for possible abnormal foreign body reaction and report it to establish the safety and efficacy profile of this material.</p><h2>Other Information</h2><p dir="ltr">Published in: World Neurosurgery<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.wneu.2023.01.089" target="_blank">https://dx.doi.org/10.1016/j.wneu.2023.01.089</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_e4605c21e071f4a0475e94219df69f98 |
| identifier_str_mv | 10.1016/j.wneu.2023.01.089 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/25124396 |
| publishDate | 2023 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Extensive Foreign Body Reaction to Synthetic Dural Replacement After Decompressive Craniectomy with Radiological and Histopathology Evidence: Observational Case SeriesKazim Mohammed (17884289)Javeed Iqbal (5514728)Mohsin Arshad (17884292)Ala Saleem Abu-Dayeh (17884295)Issam Albozom (17545668)Abdulnasser Alyafei (17542458)Tarek ben Zabih (17884298)Sirajeddin Belkhair (17151106)Biomedical and clinical sciencesClinical sciencesNeurosciencesCerebrospinal fluid leakCraniectomyCranioplastyCSFDuraplastyExtensive foreign body reactionGranulomatous reactionSynthetic dural materials<h3>Background</h3><p dir="ltr">Though the indications are quite varied, decompressive craniectomy is considered a life-saving procedure. Maximal effectiveness of craniectomy is achieved when, in addition to bone removal, the dura mater is opened properly and is augmented with duraplasty. Different synthetic materials have been used over the decades to replace the dura during decompressive craniectomy. We have used different synthetic dural replacements at our institution, including Neuro-Patch, DuraGen, and Lyoplant. In this case series, we described 4 cases that had excessive granulation tissue formation in response to a newly used synthetic dural substitute (ReDura) after emergent decompressive craniectomy. During follow-up brain imaging at different intervals, these cases were found to have foreign body reaction in the form of excessive granulation tissue formation; additionally, 1 case had a sterile pus-like collection. The granulation tissue diagnosis was affirmed by histopathology in all 4 cases.</p><p><br></p><h3>Methods</h3><p dir="ltr">This study was an observational retrograde case series, with data obtained from electronic medical records.</p><p><br></p><h3>Results</h3><p dir="ltr">The study showed extensive foreign body giant cell reactions on preoperative computed tomography scans, indicating a very high occurrence rate of 72.4%, when ReDura was used as dural replacement.</p><p><br></p><h3>Conclusions</h3><p dir="ltr">Our experience showed that patients are prone to develop severe foreign body giant cell reactions with ReDura. Neurosurgical centers using this material should monitor patients for possible abnormal foreign body reaction and report it to establish the safety and efficacy profile of this material.</p><h2>Other Information</h2><p dir="ltr">Published in: World Neurosurgery<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.wneu.2023.01.089" target="_blank">https://dx.doi.org/10.1016/j.wneu.2023.01.089</a></p>2023-04-01T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.wneu.2023.01.089https://figshare.com/articles/journal_contribution/Extensive_Foreign_Body_Reaction_to_Synthetic_Dural_Replacement_After_Decompressive_Craniectomy_with_Radiological_and_Histopathology_Evidence_Observational_Case_Series/25124396CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/251243962023-04-01T00:00:00Z |
| spellingShingle | Extensive Foreign Body Reaction to Synthetic Dural Replacement After Decompressive Craniectomy with Radiological and Histopathology Evidence: Observational Case Series Kazim Mohammed (17884289) Biomedical and clinical sciences Clinical sciences Neurosciences Cerebrospinal fluid leak Craniectomy Cranioplasty CSF Duraplasty Extensive foreign body reaction Granulomatous reaction Synthetic dural materials |
| status_str | publishedVersion |
| title | Extensive Foreign Body Reaction to Synthetic Dural Replacement After Decompressive Craniectomy with Radiological and Histopathology Evidence: Observational Case Series |
| title_full | Extensive Foreign Body Reaction to Synthetic Dural Replacement After Decompressive Craniectomy with Radiological and Histopathology Evidence: Observational Case Series |
| title_fullStr | Extensive Foreign Body Reaction to Synthetic Dural Replacement After Decompressive Craniectomy with Radiological and Histopathology Evidence: Observational Case Series |
| title_full_unstemmed | Extensive Foreign Body Reaction to Synthetic Dural Replacement After Decompressive Craniectomy with Radiological and Histopathology Evidence: Observational Case Series |
| title_short | Extensive Foreign Body Reaction to Synthetic Dural Replacement After Decompressive Craniectomy with Radiological and Histopathology Evidence: Observational Case Series |
| title_sort | Extensive Foreign Body Reaction to Synthetic Dural Replacement After Decompressive Craniectomy with Radiological and Histopathology Evidence: Observational Case Series |
| topic | Biomedical and clinical sciences Clinical sciences Neurosciences Cerebrospinal fluid leak Craniectomy Cranioplasty CSF Duraplasty Extensive foreign body reaction Granulomatous reaction Synthetic dural materials |