Severe Immune Thrombocytopenia Following MMR Vaccination with Rapid Recovery: A Case Report and Review of Literature

<p dir="ltr">Immune thrombocytopenia (ITP) is an autoimmune disease that occurs following viral illnesses and may also infrequently occur after measles, mumps, and rubella (MMR) vaccination. ITP typically presents with the sudden appearance of a petechial rash, bruising, and/or bleed...

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Main Author: Majd Akbik (20382075) (author)
Other Authors: Dima Naddeh (20382078) (author), Anas A Ashour (20382081) (author), Azzam Ashour (20382084) (author)
Published: 2020
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author Majd Akbik (20382075)
author2 Dima Naddeh (20382078)
Anas A Ashour (20382081)
Azzam Ashour (20382084)
author2_role author
author
author
author_facet Majd Akbik (20382075)
Dima Naddeh (20382078)
Anas A Ashour (20382081)
Azzam Ashour (20382084)
author_role author
dc.creator.none.fl_str_mv Majd Akbik (20382075)
Dima Naddeh (20382078)
Anas A Ashour (20382081)
Azzam Ashour (20382084)
dc.date.none.fl_str_mv 2020-12-15T03:00:00Z
dc.identifier.none.fl_str_mv 10.2147/imcrj.s286335
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Severe_Immune_Thrombocytopenia_Following_MMR_Vaccination_with_Rapid_Recovery_A_Case_Report_and_Review_of_Literature/27959838
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Immunology
Paediatrics
immune thrombocytopenia
MMR vaccine
thrombocytopenia
case report
dc.title.none.fl_str_mv Severe Immune Thrombocytopenia Following MMR Vaccination with Rapid Recovery: A Case Report and Review of Literature
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr">Immune thrombocytopenia (ITP) is an autoimmune disease that occurs following viral illnesses and may also infrequently occur after measles, mumps, and rubella (MMR) vaccination. ITP typically presents with the sudden appearance of a petechial rash, bruising, and/or bleeding in an otherwise healthy-appearing child. However, ITP following MMR vaccine does not commonly cause severely depleted platelets. We report a case of ITP after MMR vaccination in a 13-month-old baby boy, who presented with petechial rash all over his body. The child had severe thrombocytopenia but was successfully treated with a single dose of intravenous immunoglobulin without complications. The study highlights that ITP post-MMR vaccine is an easily treatable condition.</p><h2>Other Information</h2><p dir="ltr">Published in: International Medical Case Reports Journal<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.2147/imcrj.s286335" target="_blank">https://dx.doi.org/10.2147/imcrj.s286335</a></p>
eu_rights_str_mv openAccess
id Manara2_e489362f733b1807eeda0a621a65fba8
identifier_str_mv 10.2147/imcrj.s286335
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/27959838
publishDate 2020
repository.mail.fl_str_mv
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rights_invalid_str_mv CC BY 4.0
spelling Severe Immune Thrombocytopenia Following MMR Vaccination with Rapid Recovery: A Case Report and Review of LiteratureMajd Akbik (20382075)Dima Naddeh (20382078)Anas A Ashour (20382081)Azzam Ashour (20382084)Biomedical and clinical sciencesImmunologyPaediatricsimmune thrombocytopeniaMMR vaccinethrombocytopeniacase report<p dir="ltr">Immune thrombocytopenia (ITP) is an autoimmune disease that occurs following viral illnesses and may also infrequently occur after measles, mumps, and rubella (MMR) vaccination. ITP typically presents with the sudden appearance of a petechial rash, bruising, and/or bleeding in an otherwise healthy-appearing child. However, ITP following MMR vaccine does not commonly cause severely depleted platelets. We report a case of ITP after MMR vaccination in a 13-month-old baby boy, who presented with petechial rash all over his body. The child had severe thrombocytopenia but was successfully treated with a single dose of intravenous immunoglobulin without complications. The study highlights that ITP post-MMR vaccine is an easily treatable condition.</p><h2>Other Information</h2><p dir="ltr">Published in: International Medical Case Reports Journal<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.2147/imcrj.s286335" target="_blank">https://dx.doi.org/10.2147/imcrj.s286335</a></p>2020-12-15T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.2147/imcrj.s286335https://figshare.com/articles/journal_contribution/Severe_Immune_Thrombocytopenia_Following_MMR_Vaccination_with_Rapid_Recovery_A_Case_Report_and_Review_of_Literature/27959838CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/279598382020-12-15T03:00:00Z
spellingShingle Severe Immune Thrombocytopenia Following MMR Vaccination with Rapid Recovery: A Case Report and Review of Literature
Majd Akbik (20382075)
Biomedical and clinical sciences
Immunology
Paediatrics
immune thrombocytopenia
MMR vaccine
thrombocytopenia
case report
status_str publishedVersion
title Severe Immune Thrombocytopenia Following MMR Vaccination with Rapid Recovery: A Case Report and Review of Literature
title_full Severe Immune Thrombocytopenia Following MMR Vaccination with Rapid Recovery: A Case Report and Review of Literature
title_fullStr Severe Immune Thrombocytopenia Following MMR Vaccination with Rapid Recovery: A Case Report and Review of Literature
title_full_unstemmed Severe Immune Thrombocytopenia Following MMR Vaccination with Rapid Recovery: A Case Report and Review of Literature
title_short Severe Immune Thrombocytopenia Following MMR Vaccination with Rapid Recovery: A Case Report and Review of Literature
title_sort Severe Immune Thrombocytopenia Following MMR Vaccination with Rapid Recovery: A Case Report and Review of Literature
topic Biomedical and clinical sciences
Immunology
Paediatrics
immune thrombocytopenia
MMR vaccine
thrombocytopenia
case report