Association between 23 urinary VOC metabolites and cardiovascular disease among NHANES participants
<p dir="ltr">This paper reports on the association between urine concentrations of Volatile Organic Compounds (UVOCs) metabolites and Cardiovascular Diseases (CVDs). This cross-sectional study uses a sample of participants from the NHANES (2017–2020). We assessed the dose association...
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| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , , , , , |
| منشور في: |
2025
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| _version_ | 1864513513495461888 |
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| author | Lubna A. Zar (20495582) |
| author2 | Munirah Altaissan (20495585) Haya Rahimi (20495588) Rayyan Mukhtar (20495591) Sara Alailah (20495594) Hamad Almahdi (20495597) Abdulla Al-Kaabi (20495600) Rafif Abdulaziz Mahmood (20495603) Salma Mawfek Khaled (14159013) Giridhara Rathnaiah Babu (17933762) |
| author2_role | author author author author author author author author author |
| author_facet | Lubna A. Zar (20495582) Munirah Altaissan (20495585) Haya Rahimi (20495588) Rayyan Mukhtar (20495591) Sara Alailah (20495594) Hamad Almahdi (20495597) Abdulla Al-Kaabi (20495600) Rafif Abdulaziz Mahmood (20495603) Salma Mawfek Khaled (14159013) Giridhara Rathnaiah Babu (17933762) |
| author_role | author |
| dc.creator.none.fl_str_mv | Lubna A. Zar (20495582) Munirah Altaissan (20495585) Haya Rahimi (20495588) Rayyan Mukhtar (20495591) Sara Alailah (20495594) Hamad Almahdi (20495597) Abdulla Al-Kaabi (20495600) Rafif Abdulaziz Mahmood (20495603) Salma Mawfek Khaled (14159013) Giridhara Rathnaiah Babu (17933762) |
| dc.date.none.fl_str_mv | 2025-01-02T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1080/00207233.2024.2444195 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Association_between_23_urinary_VOC_metabolites_and_cardiovascular_disease_among_NHANES_participants/30173527 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Cardiovascular medicine and haematology Health sciences Epidemiology Public health NHANES VOCs CVD metabolites BTEX stroke myocardial infarction |
| dc.title.none.fl_str_mv | Association between 23 urinary VOC metabolites and cardiovascular disease among NHANES participants |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">This paper reports on the association between urine concentrations of Volatile Organic Compounds (UVOCs) metabolites and Cardiovascular Diseases (CVDs). This cross-sectional study uses a sample of participants from the NHANES (2017–2020). We assessed the dose association of UVOCs with CVD by running multivariable logistic regression models at the second, third and fourth quartiles. Among 2,363 participants in the National Health and Nutrition Examination Survey (NHANES) who had complete UVOC and CVD disease data, 11.9% (<i>N</i> = 282) had at least one cardiovascular disease event. The UVOCs of Acrolein (aOR 2.26, 95%CI 1.24–4.12 <i>p</i> = 0.01), Acrylamide (aOR 1.81, 95%CI 1.20–2.73, <i>p</i> = 0.006), 1,3-Butadiene (aOR 2.06 95%CI 1.13–3.75, <i>p</i> = 0.019), Propylene oxide (2.12, 95%CI 1.22–3.70, <i>p</i> = 0.01) in quartile-4 were associated with higher odds of CVDs. At high concentrations, metabolites of Benzene, Acrolein, Acrylonitrile, 1,3-Butadiene, and Crotonaldehyde increase the odds of developing stroke.</p><h2>Other Information</h2><p dir="ltr">Published in: International Journal of Environmental Studies<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1080/00207233.2024.2444195" target="_blank">https://dx.doi.org/10.1080/00207233.2024.2444195</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_e5fd1ede6996318da293ecee37088fe4 |
| identifier_str_mv | 10.1080/00207233.2024.2444195 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/30173527 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Association between 23 urinary VOC metabolites and cardiovascular disease among NHANES participantsLubna A. Zar (20495582)Munirah Altaissan (20495585)Haya Rahimi (20495588)Rayyan Mukhtar (20495591)Sara Alailah (20495594)Hamad Almahdi (20495597)Abdulla Al-Kaabi (20495600)Rafif Abdulaziz Mahmood (20495603)Salma Mawfek Khaled (14159013)Giridhara Rathnaiah Babu (17933762)Biomedical and clinical sciencesCardiovascular medicine and haematologyHealth sciencesEpidemiologyPublic healthNHANESVOCsCVDmetabolitesBTEXstrokemyocardial infarction<p dir="ltr">This paper reports on the association between urine concentrations of Volatile Organic Compounds (UVOCs) metabolites and Cardiovascular Diseases (CVDs). This cross-sectional study uses a sample of participants from the NHANES (2017–2020). We assessed the dose association of UVOCs with CVD by running multivariable logistic regression models at the second, third and fourth quartiles. Among 2,363 participants in the National Health and Nutrition Examination Survey (NHANES) who had complete UVOC and CVD disease data, 11.9% (<i>N</i> = 282) had at least one cardiovascular disease event. The UVOCs of Acrolein (aOR 2.26, 95%CI 1.24–4.12 <i>p</i> = 0.01), Acrylamide (aOR 1.81, 95%CI 1.20–2.73, <i>p</i> = 0.006), 1,3-Butadiene (aOR 2.06 95%CI 1.13–3.75, <i>p</i> = 0.019), Propylene oxide (2.12, 95%CI 1.22–3.70, <i>p</i> = 0.01) in quartile-4 were associated with higher odds of CVDs. At high concentrations, metabolites of Benzene, Acrolein, Acrylonitrile, 1,3-Butadiene, and Crotonaldehyde increase the odds of developing stroke.</p><h2>Other Information</h2><p dir="ltr">Published in: International Journal of Environmental Studies<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1080/00207233.2024.2444195" target="_blank">https://dx.doi.org/10.1080/00207233.2024.2444195</a></p>2025-01-02T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1080/00207233.2024.2444195https://figshare.com/articles/journal_contribution/Association_between_23_urinary_VOC_metabolites_and_cardiovascular_disease_among_NHANES_participants/30173527CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/301735272025-01-02T03:00:00Z |
| spellingShingle | Association between 23 urinary VOC metabolites and cardiovascular disease among NHANES participants Lubna A. Zar (20495582) Biomedical and clinical sciences Cardiovascular medicine and haematology Health sciences Epidemiology Public health NHANES VOCs CVD metabolites BTEX stroke myocardial infarction |
| status_str | publishedVersion |
| title | Association between 23 urinary VOC metabolites and cardiovascular disease among NHANES participants |
| title_full | Association between 23 urinary VOC metabolites and cardiovascular disease among NHANES participants |
| title_fullStr | Association between 23 urinary VOC metabolites and cardiovascular disease among NHANES participants |
| title_full_unstemmed | Association between 23 urinary VOC metabolites and cardiovascular disease among NHANES participants |
| title_short | Association between 23 urinary VOC metabolites and cardiovascular disease among NHANES participants |
| title_sort | Association between 23 urinary VOC metabolites and cardiovascular disease among NHANES participants |
| topic | Biomedical and clinical sciences Cardiovascular medicine and haematology Health sciences Epidemiology Public health NHANES VOCs CVD metabolites BTEX stroke myocardial infarction |