Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine
<p dir="ltr">The global burden of influenza-associated respiratory mortality is higher than previous estimates, with over 0.6 million deaths per year and additional mortality rates attributed to non-respiratory but influenza-related illnesses [1]. Numerous vaccines have been develope...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , |
| منشور في: |
2020
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| الموضوعات: | |
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إضافة وسم
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| _version_ | 1864513512272822272 |
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| author | Salman M. Toor (8854751) |
| author2 | Varun Sasidharan Nair (5396393) Eyad Elkord (5396390) |
| author2_role | author author |
| author_facet | Salman M. Toor (8854751) Varun Sasidharan Nair (5396393) Eyad Elkord (5396390) |
| author_role | author |
| dc.creator.none.fl_str_mv | Salman M. Toor (8854751) Varun Sasidharan Nair (5396393) Eyad Elkord (5396390) |
| dc.date.none.fl_str_mv | 2020-07-01T00:00:00Z |
| dc.identifier.none.fl_str_mv | 10.3390/vaccines8030376 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Editorial_of_Harnessing_the_Power_of_T_Cells_The_Promising_Hope_for_a_Universal_Influenza_Vaccine/26114458 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Pharmacology and pharmaceutical sciences Influenza vaccines Universal influenza vaccine Memory T cells T cell epitopes Viral immune evasion |
| dc.title.none.fl_str_mv | Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">The global burden of influenza-associated respiratory mortality is higher than previous estimates, with over 0.6 million deaths per year and additional mortality rates attributed to non-respiratory but influenza-related illnesses [1]. Numerous vaccines have been developed to protect against influenza infections. However, the efficacies of current influenza vaccines, which include cell-based vaccines, recombinant vaccines, inactivated influenza vaccine (IIV) and live attenuated influenza vaccine (LAIV) have dropped in recent years and do not provide long-term viral defense. Moreover, the hemagglutination inhibition (HAI) titers are widely considered to correlate with protection against influenza; however, patients with high titers have also been infected by influenza, while others without titers were protected [2]. Therefore, there is a real need to explore novel candidates of vaccine development and decrease mortality rates.</p><h2>Other Information</h2><p dir="ltr">Published in: Vaccines<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/vaccines8030376" target="_blank">https://dx.doi.org/10.3390/vaccines8030376</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_e7e2bdd618b785ea19122b3ab321553a |
| identifier_str_mv | 10.3390/vaccines8030376 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/26114458 |
| publishDate | 2020 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza VaccineSalman M. Toor (8854751)Varun Sasidharan Nair (5396393)Eyad Elkord (5396390)Biomedical and clinical sciencesClinical sciencesPharmacology and pharmaceutical sciencesInfluenza vaccinesUniversal influenza vaccineMemory T cellsT cell epitopesViral immune evasion<p dir="ltr">The global burden of influenza-associated respiratory mortality is higher than previous estimates, with over 0.6 million deaths per year and additional mortality rates attributed to non-respiratory but influenza-related illnesses [1]. Numerous vaccines have been developed to protect against influenza infections. However, the efficacies of current influenza vaccines, which include cell-based vaccines, recombinant vaccines, inactivated influenza vaccine (IIV) and live attenuated influenza vaccine (LAIV) have dropped in recent years and do not provide long-term viral defense. Moreover, the hemagglutination inhibition (HAI) titers are widely considered to correlate with protection against influenza; however, patients with high titers have also been infected by influenza, while others without titers were protected [2]. Therefore, there is a real need to explore novel candidates of vaccine development and decrease mortality rates.</p><h2>Other Information</h2><p dir="ltr">Published in: Vaccines<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/vaccines8030376" target="_blank">https://dx.doi.org/10.3390/vaccines8030376</a></p>2020-07-01T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.3390/vaccines8030376https://figshare.com/articles/journal_contribution/Editorial_of_Harnessing_the_Power_of_T_Cells_The_Promising_Hope_for_a_Universal_Influenza_Vaccine/26114458CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/261144582020-07-01T00:00:00Z |
| spellingShingle | Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine Salman M. Toor (8854751) Biomedical and clinical sciences Clinical sciences Pharmacology and pharmaceutical sciences Influenza vaccines Universal influenza vaccine Memory T cells T cell epitopes Viral immune evasion |
| status_str | publishedVersion |
| title | Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine |
| title_full | Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine |
| title_fullStr | Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine |
| title_full_unstemmed | Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine |
| title_short | Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine |
| title_sort | Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine |
| topic | Biomedical and clinical sciences Clinical sciences Pharmacology and pharmaceutical sciences Influenza vaccines Universal influenza vaccine Memory T cells T cell epitopes Viral immune evasion |