Characterization of a loss-of-function NSF attachment protein beta mutation in monozygotic triplets affected with epilepsy and autism using cortical neurons from proband-derived and CRISPR-corrected induced pluripotent stem cell lines

<p dir="ltr">We investigated whether a homozygous recessive genetic variant of NSF attachment protein beta (NAPB) gene inherited by monozygotic triplets contributed to their phenotype of early-onset epilepsy and autism. Induced pluripotent stem cell (iPSC) lines were generated from a...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Gowher Ali (14152593) (author)
مؤلفون آخرون: Kyung Chul Shin (13913556) (author), Wesal Habbab (17346961) (author), Ghaneya Alkhadairi (17346964) (author), Alice AbdelAleem (17753799) (author), Fouad A. AlShaban (17753802) (author), Yongsoo Park (761850) (author), Lawrence W. Stanton (6707191) (author)
منشور في: 2024
الموضوعات:
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!