Perioperative diabetes insipidus: Report of two unusual cases
<p>Diabetes insipidus (DI) is a rare clinical condition in the postoperative period. Post-surgery polyuria is a common finding, as the body excretes the excessive fluid given during surgery. It is important to diagnose and differentiate the DI from post-operative polyuria, as DI can lead to se...
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2022
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| _version_ | 1864513536530579456 |
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| author | Nissar Shaikh (11659441) |
| author2 | Muhammad Z. Labathkhan (17545617) Qazi Zeeshan (17545620) Lance Marcus (17545623) Abdulqadir J. Nashwan (11659453) |
| author2_role | author author author author |
| author_facet | Nissar Shaikh (11659441) Muhammad Z. Labathkhan (17545617) Qazi Zeeshan (17545620) Lance Marcus (17545623) Abdulqadir J. Nashwan (11659453) |
| author_role | author |
| dc.creator.none.fl_str_mv | Nissar Shaikh (11659441) Muhammad Z. Labathkhan (17545617) Qazi Zeeshan (17545620) Lance Marcus (17545623) Abdulqadir J. Nashwan (11659453) |
| dc.date.none.fl_str_mv | 2022-09-01T00:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1016/j.jecr.2022.100121 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Perioperative_diabetes_insipidus_Report_of_two_unusual_cases/24720327 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Cervical discectomy Diabetes insipidus Desmopressin polyuria Hypernatremia Ventricular cyst |
| dc.title.none.fl_str_mv | Perioperative diabetes insipidus: Report of two unusual cases |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p>Diabetes insipidus (DI) is a rare clinical condition in the postoperative period. Post-surgery polyuria is a common finding, as the body excretes the excessive fluid given during surgery. It is important to diagnose and differentiate the DI from post-operative polyuria, as DI can lead to severe dehydration and electrolyte disturbances. We report two unusual cases of perioperative DI requiring desmopressin therapy. Case 1 A 46-year-old healthy male patient developed intraoperative DI leading to hypernatremia during the anterior cervical discectomy and fusion. Anesthesia was maintained with propofol and remifentanil target-controlled infusion (TCI). After two hours of surgery, the patient became polyuric and was passing diluted urine. He received desmopressin and hydration. The patient recovered and was transferred to the ward, then, discharged home without any clinical or neurological problems. Case 2 A 36-year-old healthy male patient underwent elective 3rd ventricular cyst excision. Pre-anesthesia assessment did not reveal any comorbidities and the surgery was uneventful. His anesthesia was maintained with propofol and remifentanil TCI (target-controlled infusion). In the postoperative period, he developed DI requiring hydration and desmopressin. The patient's further recovery was uneventful. He was discharged home through the ward. Conclusion The occurrence of DI in the above-mentioned surgeries is very rare. Both surgical procedures and anesthesia medications can cause perioperative DI.</p><h2>Other Information</h2> <p> Published in: Journal of Clinical and Translational Endocrinology: Case Reports<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.jecr.2022.100121" target="_blank">https://dx.doi.org/10.1016/j.jecr.2022.100121</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_ea35a6bcef6e94bc4659446ef48315e8 |
| identifier_str_mv | 10.1016/j.jecr.2022.100121 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/24720327 |
| publishDate | 2022 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Perioperative diabetes insipidus: Report of two unusual casesNissar Shaikh (11659441)Muhammad Z. Labathkhan (17545617)Qazi Zeeshan (17545620)Lance Marcus (17545623)Abdulqadir J. Nashwan (11659453)Biomedical and clinical sciencesClinical sciencesCervical discectomyDiabetes insipidusDesmopressin polyuriaHypernatremiaVentricular cyst<p>Diabetes insipidus (DI) is a rare clinical condition in the postoperative period. Post-surgery polyuria is a common finding, as the body excretes the excessive fluid given during surgery. It is important to diagnose and differentiate the DI from post-operative polyuria, as DI can lead to severe dehydration and electrolyte disturbances. We report two unusual cases of perioperative DI requiring desmopressin therapy. Case 1 A 46-year-old healthy male patient developed intraoperative DI leading to hypernatremia during the anterior cervical discectomy and fusion. Anesthesia was maintained with propofol and remifentanil target-controlled infusion (TCI). After two hours of surgery, the patient became polyuric and was passing diluted urine. He received desmopressin and hydration. The patient recovered and was transferred to the ward, then, discharged home without any clinical or neurological problems. Case 2 A 36-year-old healthy male patient underwent elective 3rd ventricular cyst excision. Pre-anesthesia assessment did not reveal any comorbidities and the surgery was uneventful. His anesthesia was maintained with propofol and remifentanil TCI (target-controlled infusion). In the postoperative period, he developed DI requiring hydration and desmopressin. The patient's further recovery was uneventful. He was discharged home through the ward. Conclusion The occurrence of DI in the above-mentioned surgeries is very rare. Both surgical procedures and anesthesia medications can cause perioperative DI.</p><h2>Other Information</h2> <p> Published in: Journal of Clinical and Translational Endocrinology: Case Reports<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.jecr.2022.100121" target="_blank">https://dx.doi.org/10.1016/j.jecr.2022.100121</a></p>2022-09-01T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.jecr.2022.100121https://figshare.com/articles/journal_contribution/Perioperative_diabetes_insipidus_Report_of_two_unusual_cases/24720327CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/247203272022-09-01T00:00:00Z |
| spellingShingle | Perioperative diabetes insipidus: Report of two unusual cases Nissar Shaikh (11659441) Biomedical and clinical sciences Clinical sciences Cervical discectomy Diabetes insipidus Desmopressin polyuria Hypernatremia Ventricular cyst |
| status_str | publishedVersion |
| title | Perioperative diabetes insipidus: Report of two unusual cases |
| title_full | Perioperative diabetes insipidus: Report of two unusual cases |
| title_fullStr | Perioperative diabetes insipidus: Report of two unusual cases |
| title_full_unstemmed | Perioperative diabetes insipidus: Report of two unusual cases |
| title_short | Perioperative diabetes insipidus: Report of two unusual cases |
| title_sort | Perioperative diabetes insipidus: Report of two unusual cases |
| topic | Biomedical and clinical sciences Clinical sciences Cervical discectomy Diabetes insipidus Desmopressin polyuria Hypernatremia Ventricular cyst |