A study of 18F-FLT positron emission tomography/computed tomography imaging in cases of prefibrotic/early primary myelofibrosis and essential thrombocythemia

<p dir="ltr">The objectives of this research project are to study in patients with primary myelofibrosis (PMF) and Essential Thrombocythemia (ET); (1) the uptake patterns of 18FLT-PET (FLT-PET) and its value in diagnosing, staging, and treatment response monitoring of malignant hemat...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Mohamed A. Yassin (16322749) (author)
مؤلفون آخرون: Sadek A. Nehmeh (10726435) (author), Abdulqadir J. Nashwan (16328993) (author), Samah A. Kohla (16561317) (author), Shehab F. Mohamed (16561320) (author), Omar M. Ismail (16515229) (author), Ahmad Al Sabbagh (8984087) (author), Firyal Ibrahim (8984078) (author), Dina S. Soliman (16515232) (author), Lajos Szabados (16561323) (author), Hadi Fayad (16561325) (author)
منشور في: 2020
الموضوعات:
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author Mohamed A. Yassin (16322749)
author2 Sadek A. Nehmeh (10726435)
Abdulqadir J. Nashwan (16328993)
Samah A. Kohla (16561317)
Shehab F. Mohamed (16561320)
Omar M. Ismail (16515229)
Ahmad Al Sabbagh (8984087)
Firyal Ibrahim (8984078)
Dina S. Soliman (16515232)
Lajos Szabados (16561323)
Hadi Fayad (16561325)
author2_role author
author
author
author
author
author
author
author
author
author
author_facet Mohamed A. Yassin (16322749)
Sadek A. Nehmeh (10726435)
Abdulqadir J. Nashwan (16328993)
Samah A. Kohla (16561317)
Shehab F. Mohamed (16561320)
Omar M. Ismail (16515229)
Ahmad Al Sabbagh (8984087)
Firyal Ibrahim (8984078)
Dina S. Soliman (16515232)
Lajos Szabados (16561323)
Hadi Fayad (16561325)
author_role author
dc.creator.none.fl_str_mv Mohamed A. Yassin (16322749)
Sadek A. Nehmeh (10726435)
Abdulqadir J. Nashwan (16328993)
Samah A. Kohla (16561317)
Shehab F. Mohamed (16561320)
Omar M. Ismail (16515229)
Ahmad Al Sabbagh (8984087)
Firyal Ibrahim (8984078)
Dina S. Soliman (16515232)
Lajos Szabados (16561323)
Hadi Fayad (16561325)
dc.date.none.fl_str_mv 2020-11-06T00:00:00Z
dc.identifier.none.fl_str_mv 10.1097/md.0000000000023088
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/A_study_of_18F-FLT_positron_emission_tomography_computed_tomography_imaging_in_cases_of_prefibrotic_early_primary_myelofibrosis_and_essential_thrombocythemia/23701695
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Cardiovascular medicine and haematology
Oncology and carcinogenesis
fluorothymidine F-18
positron emission tomography
essential thrombocythemia
prefibrotic/early primary myelofibrosis
dc.title.none.fl_str_mv A study of 18F-FLT positron emission tomography/computed tomography imaging in cases of prefibrotic/early primary myelofibrosis and essential thrombocythemia
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr">The objectives of this research project are to study in patients with primary myelofibrosis (PMF) and Essential Thrombocythemia (ET); (1) the uptake patterns of 18FLT-PET (FLT-PET) and its value in diagnosing, staging, and treatment response monitoring of malignant hematopoiesis, (2) compare imaging findings from FLT-PET with bone marrow biopsy (standard of care), and (3) associate FLT-PET uptake patterns with genetic makeup such as JAK2 (Janus kinase 2), CALR (Calreticulin), MPL (myeloproliferative leukemia protein), Triple negative disease, and allele burden.</p><h2>Other Information</h2><p dir="ltr">Published in: Medicine<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1097/md.0000000000023088" target="_blank">http://dx.doi.org/10.1097/md.0000000000023088</a></p><p dir="ltr">Additional institutions affiliated with: PET-CT Center for Diagnosis and Research - HMC</p>
eu_rights_str_mv openAccess
id Manara2_ef6ece85320d1e97cd442efdd36c3312
identifier_str_mv 10.1097/md.0000000000023088
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/23701695
publishDate 2020
repository.mail.fl_str_mv
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rights_invalid_str_mv CC BY 4.0
spelling A study of 18F-FLT positron emission tomography/computed tomography imaging in cases of prefibrotic/early primary myelofibrosis and essential thrombocythemiaMohamed A. Yassin (16322749)Sadek A. Nehmeh (10726435)Abdulqadir J. Nashwan (16328993)Samah A. Kohla (16561317)Shehab F. Mohamed (16561320)Omar M. Ismail (16515229)Ahmad Al Sabbagh (8984087)Firyal Ibrahim (8984078)Dina S. Soliman (16515232)Lajos Szabados (16561323)Hadi Fayad (16561325)Biomedical and clinical sciencesCardiovascular medicine and haematologyOncology and carcinogenesisfluorothymidine F-18positron emission tomographyessential thrombocythemiaprefibrotic/early primary myelofibrosis<p dir="ltr">The objectives of this research project are to study in patients with primary myelofibrosis (PMF) and Essential Thrombocythemia (ET); (1) the uptake patterns of 18FLT-PET (FLT-PET) and its value in diagnosing, staging, and treatment response monitoring of malignant hematopoiesis, (2) compare imaging findings from FLT-PET with bone marrow biopsy (standard of care), and (3) associate FLT-PET uptake patterns with genetic makeup such as JAK2 (Janus kinase 2), CALR (Calreticulin), MPL (myeloproliferative leukemia protein), Triple negative disease, and allele burden.</p><h2>Other Information</h2><p dir="ltr">Published in: Medicine<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1097/md.0000000000023088" target="_blank">http://dx.doi.org/10.1097/md.0000000000023088</a></p><p dir="ltr">Additional institutions affiliated with: PET-CT Center for Diagnosis and Research - HMC</p>2020-11-06T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1097/md.0000000000023088https://figshare.com/articles/journal_contribution/A_study_of_18F-FLT_positron_emission_tomography_computed_tomography_imaging_in_cases_of_prefibrotic_early_primary_myelofibrosis_and_essential_thrombocythemia/23701695CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/237016952020-11-06T00:00:00Z
spellingShingle A study of 18F-FLT positron emission tomography/computed tomography imaging in cases of prefibrotic/early primary myelofibrosis and essential thrombocythemia
Mohamed A. Yassin (16322749)
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Oncology and carcinogenesis
fluorothymidine F-18
positron emission tomography
essential thrombocythemia
prefibrotic/early primary myelofibrosis
status_str publishedVersion
title A study of 18F-FLT positron emission tomography/computed tomography imaging in cases of prefibrotic/early primary myelofibrosis and essential thrombocythemia
title_full A study of 18F-FLT positron emission tomography/computed tomography imaging in cases of prefibrotic/early primary myelofibrosis and essential thrombocythemia
title_fullStr A study of 18F-FLT positron emission tomography/computed tomography imaging in cases of prefibrotic/early primary myelofibrosis and essential thrombocythemia
title_full_unstemmed A study of 18F-FLT positron emission tomography/computed tomography imaging in cases of prefibrotic/early primary myelofibrosis and essential thrombocythemia
title_short A study of 18F-FLT positron emission tomography/computed tomography imaging in cases of prefibrotic/early primary myelofibrosis and essential thrombocythemia
title_sort A study of 18F-FLT positron emission tomography/computed tomography imaging in cases of prefibrotic/early primary myelofibrosis and essential thrombocythemia
topic Biomedical and clinical sciences
Cardiovascular medicine and haematology
Oncology and carcinogenesis
fluorothymidine F-18
positron emission tomography
essential thrombocythemia
prefibrotic/early primary myelofibrosis