Epidemiology, clinical characteristics, and associated cost of acute poisoning: a retrospective study

<h3>Introduction </h3><p dir="ltr">Poisoning is a major public health issue and a leading cause of admission to the emergency department (ED). There is a paucity of data describing the epidemiology and cost of acute poisoning. Therefore, this study investigated the epidem...

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Main Author: Waleed Salem (19794156) (author)
Other Authors: Pallivalappila Abdulrouf (21839378) (author), Binny Thomas (5801969) (author), Wessam Elkassem (18472434) (author), Dina Abushanab (10696501) (author), Haseebur Rahman Khan (21839381) (author), Yolande Hanssens (14151507) (author), Rajvir Singh (315457) (author), Hany A. Zaki (17337673) (author), Aftab Mohammed Azad (21839384) (author), Moza Al Hail (2511859) (author), Shaban Mohammed (14150130) (author)
Published: 2024
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_version_ 1864513543088373760
author Waleed Salem (19794156)
author2 Pallivalappila Abdulrouf (21839378)
Binny Thomas (5801969)
Wessam Elkassem (18472434)
Dina Abushanab (10696501)
Haseebur Rahman Khan (21839381)
Yolande Hanssens (14151507)
Rajvir Singh (315457)
Hany A. Zaki (17337673)
Aftab Mohammed Azad (21839384)
Moza Al Hail (2511859)
Shaban Mohammed (14150130)
author2_role author
author
author
author
author
author
author
author
author
author
author
author_facet Waleed Salem (19794156)
Pallivalappila Abdulrouf (21839378)
Binny Thomas (5801969)
Wessam Elkassem (18472434)
Dina Abushanab (10696501)
Haseebur Rahman Khan (21839381)
Yolande Hanssens (14151507)
Rajvir Singh (315457)
Hany A. Zaki (17337673)
Aftab Mohammed Azad (21839384)
Moza Al Hail (2511859)
Shaban Mohammed (14150130)
author_role author
dc.creator.none.fl_str_mv Waleed Salem (19794156)
Pallivalappila Abdulrouf (21839378)
Binny Thomas (5801969)
Wessam Elkassem (18472434)
Dina Abushanab (10696501)
Haseebur Rahman Khan (21839381)
Yolande Hanssens (14151507)
Rajvir Singh (315457)
Hany A. Zaki (17337673)
Aftab Mohammed Azad (21839384)
Moza Al Hail (2511859)
Shaban Mohammed (14150130)
dc.date.none.fl_str_mv 2024-05-10T09:00:00Z
dc.identifier.none.fl_str_mv 10.1080/20523211.2024.2325513
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Epidemiology_clinical_characteristics_and_associated_cost_of_acute_poisoning_a_retrospective_study/29713814
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Pharmacology and pharmaceutical sciences
Health sciences
Epidemiology
Public health
Epidemiology
acute poisoning
emergency department (ED)
cost
Qatar
dc.title.none.fl_str_mv Epidemiology, clinical characteristics, and associated cost of acute poisoning: a retrospective study
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3>Introduction </h3><p dir="ltr">Poisoning is a major public health issue and a leading cause of admission to the emergency department (ED). There is a paucity of data describing the epidemiology and cost of acute poisoning. Therefore, this study investigated the epidemiology, patterns, and associated costs of acute poisoning in emergency department of the largest tertiary care healthcare centre in Qatar. </p><h3>Method</h3><p dir="ltr">This study was a retrospective review of the health records of patients admitted to the ED due to poisoning between January 2015 and December 2019. Incidence, clinical characteristics, and costs associated with acute poisoning were assessed. Frequency and percentages were calculated for categorical variables and mean and SD for continuous variables. The relationship between sociodemographic characteristics and poisoning profile was assessed using the chi-square test. A micro-costing approach using the cost of each resource was applied for cost calculations. </p><h3>Result</h3><p dir="ltr">The incidence of acute poisoning was 178 cases per 100,000 patients. Females (56%) and children below 14 years (44.3%) accounted for the largest proportion. Most of the exposures were accidental involving therapeutic agents (64.2%). The mean length of hospital stay was found to be 1.84 ± 0.81 days, and most patients (76.6%) were discharged within the first 8 h. A statistically significant difference was found between age groups and type of toxin (χ<sup>2</sup> = 23.3, p < 0.001), cause and route of exposure (χ<sup>2</sup> = 42.2, <i>p</i> < 0.001), and length of hospital stay (χ<sup>2</sup> = 113.16, <i>p</i> < 0.001). Admission to intensive care units had the highest cost expenditure (USD 326,008), while general wards accounted for the least (USD 57,709). </p><h3>Conclusion</h3><p dir="ltr">Unintentional poisoning by pharmacological agents is common in infants and children. This study will assist in the development of educational and preventive programmes to minimise exposure to toxic agents. Further studies are required to explore the impact of medical toxicology services, and post discharge monitoring of poisonin</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Pharmaceutical Policy and Practice<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1080/20523211.2024.2325513" target="_blank">https://dx.doi.org/10.1080/20523211.2024.2325513</a></p>
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identifier_str_mv 10.1080/20523211.2024.2325513
network_acronym_str Manara2
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oai_identifier_str oai:figshare.com:article/29713814
publishDate 2024
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spelling Epidemiology, clinical characteristics, and associated cost of acute poisoning: a retrospective studyWaleed Salem (19794156)Pallivalappila Abdulrouf (21839378)Binny Thomas (5801969)Wessam Elkassem (18472434)Dina Abushanab (10696501)Haseebur Rahman Khan (21839381)Yolande Hanssens (14151507)Rajvir Singh (315457)Hany A. Zaki (17337673)Aftab Mohammed Azad (21839384)Moza Al Hail (2511859)Shaban Mohammed (14150130)Biomedical and clinical sciencesPharmacology and pharmaceutical sciencesHealth sciencesEpidemiologyPublic healthEpidemiologyacute poisoningemergency department (ED)costQatar<h3>Introduction </h3><p dir="ltr">Poisoning is a major public health issue and a leading cause of admission to the emergency department (ED). There is a paucity of data describing the epidemiology and cost of acute poisoning. Therefore, this study investigated the epidemiology, patterns, and associated costs of acute poisoning in emergency department of the largest tertiary care healthcare centre in Qatar. </p><h3>Method</h3><p dir="ltr">This study was a retrospective review of the health records of patients admitted to the ED due to poisoning between January 2015 and December 2019. Incidence, clinical characteristics, and costs associated with acute poisoning were assessed. Frequency and percentages were calculated for categorical variables and mean and SD for continuous variables. The relationship between sociodemographic characteristics and poisoning profile was assessed using the chi-square test. A micro-costing approach using the cost of each resource was applied for cost calculations. </p><h3>Result</h3><p dir="ltr">The incidence of acute poisoning was 178 cases per 100,000 patients. Females (56%) and children below 14 years (44.3%) accounted for the largest proportion. Most of the exposures were accidental involving therapeutic agents (64.2%). The mean length of hospital stay was found to be 1.84 ± 0.81 days, and most patients (76.6%) were discharged within the first 8 h. A statistically significant difference was found between age groups and type of toxin (χ<sup>2</sup> = 23.3, p < 0.001), cause and route of exposure (χ<sup>2</sup> = 42.2, <i>p</i> < 0.001), and length of hospital stay (χ<sup>2</sup> = 113.16, <i>p</i> < 0.001). Admission to intensive care units had the highest cost expenditure (USD 326,008), while general wards accounted for the least (USD 57,709). </p><h3>Conclusion</h3><p dir="ltr">Unintentional poisoning by pharmacological agents is common in infants and children. This study will assist in the development of educational and preventive programmes to minimise exposure to toxic agents. Further studies are required to explore the impact of medical toxicology services, and post discharge monitoring of poisonin</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Pharmaceutical Policy and Practice<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1080/20523211.2024.2325513" target="_blank">https://dx.doi.org/10.1080/20523211.2024.2325513</a></p>2024-05-10T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1080/20523211.2024.2325513https://figshare.com/articles/journal_contribution/Epidemiology_clinical_characteristics_and_associated_cost_of_acute_poisoning_a_retrospective_study/29713814CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/297138142024-05-10T09:00:00Z
spellingShingle Epidemiology, clinical characteristics, and associated cost of acute poisoning: a retrospective study
Waleed Salem (19794156)
Biomedical and clinical sciences
Pharmacology and pharmaceutical sciences
Health sciences
Epidemiology
Public health
Epidemiology
acute poisoning
emergency department (ED)
cost
Qatar
status_str publishedVersion
title Epidemiology, clinical characteristics, and associated cost of acute poisoning: a retrospective study
title_full Epidemiology, clinical characteristics, and associated cost of acute poisoning: a retrospective study
title_fullStr Epidemiology, clinical characteristics, and associated cost of acute poisoning: a retrospective study
title_full_unstemmed Epidemiology, clinical characteristics, and associated cost of acute poisoning: a retrospective study
title_short Epidemiology, clinical characteristics, and associated cost of acute poisoning: a retrospective study
title_sort Epidemiology, clinical characteristics, and associated cost of acute poisoning: a retrospective study
topic Biomedical and clinical sciences
Pharmacology and pharmaceutical sciences
Health sciences
Epidemiology
Public health
Epidemiology
acute poisoning
emergency department (ED)
cost
Qatar