Material Extrusion 3D Printing (ME3DP) Process Simulations of Polymeric Porous Scaffolds for Bone Tissue Engineering
<p dir="ltr">Bone tissue engineering (BTE) is an active area of research for bone defect treatment. Some polymeric materials have recently gained adequate attention as potential materials for BTE applications, as they are biocompatible, biodegradable, inexpensive, lightweight, easy t...
محفوظ في:
| المؤلف الرئيسي: | |
|---|---|
| مؤلفون آخرون: | , |
| منشور في: |
2023
|
| الموضوعات: | |
| الوسوم: |
إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
|
| _version_ | 1864513508083761152 |
|---|---|
| author | Ramsha Imran (12431698) |
| author2 | Ans Al Rashid (14777050) Muammer Koç (8350053) |
| author2_role | author author |
| author_facet | Ramsha Imran (12431698) Ans Al Rashid (14777050) Muammer Koç (8350053) |
| author_role | author |
| dc.creator.none.fl_str_mv | Ramsha Imran (12431698) Ans Al Rashid (14777050) Muammer Koç (8350053) |
| dc.date.none.fl_str_mv | 2023-03-20T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.3390/ma16062475 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Material_Extrusion_3D_Printing_ME3DP_Process_Simulations_of_Polymeric_Porous_Scaffolds_for_Bone_Tissue_Engineering/26661541 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biological sciences Biochemistry and cell biology Engineering Biomedical engineering Materials engineering 3D printing bone tissue engineering process simulation porous scaffolds biodegradable |
| dc.title.none.fl_str_mv | Material Extrusion 3D Printing (ME3DP) Process Simulations of Polymeric Porous Scaffolds for Bone Tissue Engineering |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Bone tissue engineering (BTE) is an active area of research for bone defect treatment. Some polymeric materials have recently gained adequate attention as potential materials for BTE applications, as they are biocompatible, biodegradable, inexpensive, lightweight, easy to process, and recyclable. Polyetherimide (PEI), acrylonitrile butadiene styrene (ABS), and polyamide-12 (PA12) are potential biocompatible materials for biomedical applications due to their excellent physical, chemical, and mechanical properties. The current study presents preliminary findings on the process simulations for 3D-printed polymeric porous scaffolds for a material extrusion 3D printing (ME3DP) process to observe the manufacturing constraints and scaffold quality with respect to designed structures (porous scaffolds). Different unit cell designs (ventils, grid, and octet) for porous scaffolds, virtually fabricated using three polymeric materials (PEI, ABS, and PA12), were investigated for process-induced defections and residual stresses. The numerical simulation results concluded that higher dimensional accuracy and control were achieved for grid unit cell scaffolds manufactured using PEI material; however, minimum residual stresses were achieved for grid unit cell scaffolds fabricated using PA12 material. Future studies will include the experimental validation of numerical simulation results and the biomechanical performance of 3D-printed polymeric scaffolds.</p><h2>Other Information</h2><p dir="ltr">Published in: Materials<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/ma16062475" target="_blank">https://dx.doi.org/10.3390/ma16062475</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_f3015a2ac67bb7e7f4964568fc93dc57 |
| identifier_str_mv | 10.3390/ma16062475 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/26661541 |
| publishDate | 2023 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Material Extrusion 3D Printing (ME3DP) Process Simulations of Polymeric Porous Scaffolds for Bone Tissue EngineeringRamsha Imran (12431698)Ans Al Rashid (14777050)Muammer Koç (8350053)Biological sciencesBiochemistry and cell biologyEngineeringBiomedical engineeringMaterials engineering3D printingbone tissue engineeringprocess simulationporous scaffoldsbiodegradable<p dir="ltr">Bone tissue engineering (BTE) is an active area of research for bone defect treatment. Some polymeric materials have recently gained adequate attention as potential materials for BTE applications, as they are biocompatible, biodegradable, inexpensive, lightweight, easy to process, and recyclable. Polyetherimide (PEI), acrylonitrile butadiene styrene (ABS), and polyamide-12 (PA12) are potential biocompatible materials for biomedical applications due to their excellent physical, chemical, and mechanical properties. The current study presents preliminary findings on the process simulations for 3D-printed polymeric porous scaffolds for a material extrusion 3D printing (ME3DP) process to observe the manufacturing constraints and scaffold quality with respect to designed structures (porous scaffolds). Different unit cell designs (ventils, grid, and octet) for porous scaffolds, virtually fabricated using three polymeric materials (PEI, ABS, and PA12), were investigated for process-induced defections and residual stresses. The numerical simulation results concluded that higher dimensional accuracy and control were achieved for grid unit cell scaffolds manufactured using PEI material; however, minimum residual stresses were achieved for grid unit cell scaffolds fabricated using PA12 material. Future studies will include the experimental validation of numerical simulation results and the biomechanical performance of 3D-printed polymeric scaffolds.</p><h2>Other Information</h2><p dir="ltr">Published in: Materials<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/ma16062475" target="_blank">https://dx.doi.org/10.3390/ma16062475</a></p>2023-03-20T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.3390/ma16062475https://figshare.com/articles/journal_contribution/Material_Extrusion_3D_Printing_ME3DP_Process_Simulations_of_Polymeric_Porous_Scaffolds_for_Bone_Tissue_Engineering/26661541CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/266615412023-03-20T09:00:00Z |
| spellingShingle | Material Extrusion 3D Printing (ME3DP) Process Simulations of Polymeric Porous Scaffolds for Bone Tissue Engineering Ramsha Imran (12431698) Biological sciences Biochemistry and cell biology Engineering Biomedical engineering Materials engineering 3D printing bone tissue engineering process simulation porous scaffolds biodegradable |
| status_str | publishedVersion |
| title | Material Extrusion 3D Printing (ME3DP) Process Simulations of Polymeric Porous Scaffolds for Bone Tissue Engineering |
| title_full | Material Extrusion 3D Printing (ME3DP) Process Simulations of Polymeric Porous Scaffolds for Bone Tissue Engineering |
| title_fullStr | Material Extrusion 3D Printing (ME3DP) Process Simulations of Polymeric Porous Scaffolds for Bone Tissue Engineering |
| title_full_unstemmed | Material Extrusion 3D Printing (ME3DP) Process Simulations of Polymeric Porous Scaffolds for Bone Tissue Engineering |
| title_short | Material Extrusion 3D Printing (ME3DP) Process Simulations of Polymeric Porous Scaffolds for Bone Tissue Engineering |
| title_sort | Material Extrusion 3D Printing (ME3DP) Process Simulations of Polymeric Porous Scaffolds for Bone Tissue Engineering |
| topic | Biological sciences Biochemistry and cell biology Engineering Biomedical engineering Materials engineering 3D printing bone tissue engineering process simulation porous scaffolds biodegradable |