Forging the path to precision medicine in Qatar: a public health perspective on pharmacogenomics initiatives
<p dir="ltr">Pharmacogenomics (PGx) is an important component of precision medicine that promises tailored treatment approaches based on an individual’s genetic information. Exploring the initiatives in research that help to integrate PGx test into clinical setting, identifying the p...
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2024
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| _version_ | 1864513509852708864 |
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| author | Kholoud Bastaki (18434094) |
| author2 | Dinesh Velayutham (5444072) Areeba Irfan (19255795) Mohd Adnan (11125607) Sawsan Mohammed (19255798) Hamdi Mbarek (134997) M. Waild Qoronfleh (19255801) Puthen Veettil Jithesh (12040358) |
| author2_role | author author author author author author author |
| author_facet | Kholoud Bastaki (18434094) Dinesh Velayutham (5444072) Areeba Irfan (19255795) Mohd Adnan (11125607) Sawsan Mohammed (19255798) Hamdi Mbarek (134997) M. Waild Qoronfleh (19255801) Puthen Veettil Jithesh (12040358) |
| author_role | author |
| dc.creator.none.fl_str_mv | Kholoud Bastaki (18434094) Dinesh Velayutham (5444072) Areeba Irfan (19255795) Mohd Adnan (11125607) Sawsan Mohammed (19255798) Hamdi Mbarek (134997) M. Waild Qoronfleh (19255801) Puthen Veettil Jithesh (12040358) |
| dc.date.none.fl_str_mv | 2024-03-14T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.3389/fpubh.2024.1364221 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Forging_the_path_to_precision_medicine_in_Qatar_a_public_health_perspective_on_pharmacogenomics_initiatives/26403100 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biological sciences Genetics Biomedical and clinical sciences Clinical sciences Pharmacology and pharmaceutical sciences Health sciences Public health pharmacogenomics (PGx) population health precision health precision medicine Middle East Qatar |
| dc.title.none.fl_str_mv | Forging the path to precision medicine in Qatar: a public health perspective on pharmacogenomics initiatives |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Pharmacogenomics (PGx) is an important component of precision medicine that promises tailored treatment approaches based on an individual’s genetic information. Exploring the initiatives in research that help to integrate PGx test into clinical setting, identifying the potential barriers and challenges as well as planning the future directions, are all important for fruitful PGx implementation in any population. Qatar serves as an exemplar case study for the Middle East, having a small native population compared to a diverse immigrant population, advanced healthcare system, national genome program, and several educational initiatives on PGx and precision medicine. This paper attempts to outline the current state of PGx research and implementation in Qatar within the global context, emphasizing ongoing initiatives and educational efforts. The inclusion of PGx in university curricula and healthcare provider training, alongside precision medicine conferences, showcase Qatar’s commitment to advancing this field. However, challenges persist, including the requirement for population specific implementation strategies, complex genetic data interpretation, lack of standardization, and limited awareness. The review suggests policy development for future directions in continued research investment, conducting clinical trials for the feasibility of PGx implementation, ethical considerations, technological advancements, and global collaborations to overcome these barriers.</p><h2>Other Information</h2><p dir="ltr">Published in: Frontiers in Public Health<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fpubh.2024.1364221" target="_blank">https://dx.doi.org/10.3389/fpubh.2024.1364221</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_f4f7180c92be10a3b8b104b9b80d816c |
| identifier_str_mv | 10.3389/fpubh.2024.1364221 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/26403100 |
| publishDate | 2024 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Forging the path to precision medicine in Qatar: a public health perspective on pharmacogenomics initiativesKholoud Bastaki (18434094)Dinesh Velayutham (5444072)Areeba Irfan (19255795)Mohd Adnan (11125607)Sawsan Mohammed (19255798)Hamdi Mbarek (134997)M. Waild Qoronfleh (19255801)Puthen Veettil Jithesh (12040358)Biological sciencesGeneticsBiomedical and clinical sciencesClinical sciencesPharmacology and pharmaceutical sciencesHealth sciencesPublic healthpharmacogenomics (PGx)population healthprecision healthprecision medicineMiddle EastQatar<p dir="ltr">Pharmacogenomics (PGx) is an important component of precision medicine that promises tailored treatment approaches based on an individual’s genetic information. Exploring the initiatives in research that help to integrate PGx test into clinical setting, identifying the potential barriers and challenges as well as planning the future directions, are all important for fruitful PGx implementation in any population. Qatar serves as an exemplar case study for the Middle East, having a small native population compared to a diverse immigrant population, advanced healthcare system, national genome program, and several educational initiatives on PGx and precision medicine. This paper attempts to outline the current state of PGx research and implementation in Qatar within the global context, emphasizing ongoing initiatives and educational efforts. The inclusion of PGx in university curricula and healthcare provider training, alongside precision medicine conferences, showcase Qatar’s commitment to advancing this field. However, challenges persist, including the requirement for population specific implementation strategies, complex genetic data interpretation, lack of standardization, and limited awareness. The review suggests policy development for future directions in continued research investment, conducting clinical trials for the feasibility of PGx implementation, ethical considerations, technological advancements, and global collaborations to overcome these barriers.</p><h2>Other Information</h2><p dir="ltr">Published in: Frontiers in Public Health<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fpubh.2024.1364221" target="_blank">https://dx.doi.org/10.3389/fpubh.2024.1364221</a></p>2024-03-14T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.3389/fpubh.2024.1364221https://figshare.com/articles/journal_contribution/Forging_the_path_to_precision_medicine_in_Qatar_a_public_health_perspective_on_pharmacogenomics_initiatives/26403100CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/264031002024-03-14T09:00:00Z |
| spellingShingle | Forging the path to precision medicine in Qatar: a public health perspective on pharmacogenomics initiatives Kholoud Bastaki (18434094) Biological sciences Genetics Biomedical and clinical sciences Clinical sciences Pharmacology and pharmaceutical sciences Health sciences Public health pharmacogenomics (PGx) population health precision health precision medicine Middle East Qatar |
| status_str | publishedVersion |
| title | Forging the path to precision medicine in Qatar: a public health perspective on pharmacogenomics initiatives |
| title_full | Forging the path to precision medicine in Qatar: a public health perspective on pharmacogenomics initiatives |
| title_fullStr | Forging the path to precision medicine in Qatar: a public health perspective on pharmacogenomics initiatives |
| title_full_unstemmed | Forging the path to precision medicine in Qatar: a public health perspective on pharmacogenomics initiatives |
| title_short | Forging the path to precision medicine in Qatar: a public health perspective on pharmacogenomics initiatives |
| title_sort | Forging the path to precision medicine in Qatar: a public health perspective on pharmacogenomics initiatives |
| topic | Biological sciences Genetics Biomedical and clinical sciences Clinical sciences Pharmacology and pharmaceutical sciences Health sciences Public health pharmacogenomics (PGx) population health precision health precision medicine Middle East Qatar |