Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity

Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity

<p dir="ltr">Sedentary lifestyle and excessive energy intake are prominent contributors to obesity; a major risk factors for the development of insulin resistance, type 2 diabetes and cardiovascular diseases. Elucidating the molecular mechanisms underlying these chronic conditions is...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Mohamed Abu-Farha (18535590) (author)
مؤلفون آخرون:	Ali Tiss (437068) (author), Jehad Abubaker (18535605) (author), Abdelkrim Khadir (437074) (author), Fahad Al-Ghimlas (412125) (author), Irina Al-Khairi (437069) (author), Engin Baturcam (309036) (author), Preethi Cherian (437070) (author), Naser Elkum (79418) (author), Maha Hammad (437071) (author), Jeena John (437072) (author), Sina Kavalakatt (437073) (author), Samia Warsame (437075) (author), Kazem Behbehani (412126) (author), Said Dermime (15263545) (author), Mohammed Dehbi (14152758) (author)
منشور في:	2013
الموضوعات:	Biomedical and clinical sciences Clinical sciences Medical biochemistry and metabolomics Medical physiology Chemical sciences Medicinal and biomolecular chemistry Obesity Exercise DNA-binding proteins Adipose tissue Protein expression Computer software Cytoskeletal proteins Inflammation
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة

The Role of AEBP1 in Sex-Specific Diet-Induced Obesity
حسب: Zhang, Lei
منشور في: (2005)

Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue
حسب: Ali Tiss (437068)
منشور في: (2014)

The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polycystic Ovary Syndrome
حسب: Thozhukat Sathyapalan (704787)
منشور في: (2019)

Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese
حسب: Abdelkrim Khadir (437074)
منشور في: (2018)

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
حسب: Shadi Nejat (19457212)
منشور في: (2023)

The role of genetic and epigenetic GNAS alterations in the development of early-onset obesity
حسب: Alaa, Abbas
منشور في: (2023)

Mammary adipose dysfunction in the dual epidemic of obesity and breast cancer
حسب: Elvina Jeyakumar (22997311)
منشور في: (2025)

Expression, purification and characterization of α-synuclein fibrillar specific scFv from inclusion bodies
حسب: Vijay Gupta (209146)
منشور في: (2020)

Loss of the yeast transporter Agp2 upregulates the pleiotropic drug-resistant pump Pdr5 and confers resistance to the protein synthesis inhibitor cycloheximide
حسب: Yusra Manzoor (18599180)
منشور في: (2024)

The regulation of Rhoa in focal adhesions by starD13 is essential for astrocytoma cell motility. (c2011)
حسب: Khalil, Bassem D.
منشور في: (2011)

Antibody stability: A key to performance - Analysis, influences and improvement
حسب: Hui Ma (290168)
منشور في: (2020)

Inflammation-Modulating Biomedical Interventions for Diabetic Wound Healing: An Overview of Preclinical and Clinical Studies
حسب: Nouf N. Mahmoud (9133074)
منشور في: (2024)

Molecular forces driving protein complexation of lentil and whey proteins: Structure-function relationships of trehalose-conjugated protein complexes on protein digestibility and solubility
حسب: Mohammad, Alrosan
منشور في: (2024)

Paracrine Mechanisms of Mesenchymal Stromal Cells in Angiogenesis
حسب: Selma Maacha (501715)
منشور في: (2020)

Alterations in blood Lipoprotein & Apolipoprotein B profile induced by moderate acute & chronic alcohol intake in the rat model. (c2002)
حسب: Berberi, Rania
منشور في: (2002)

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss
حسب: Meritxell Espino Guarch (18810097)
منشور في: (2018)

Electrostatic regulation of the cis- and trans-membrane interactions of synaptotagmin-1
حسب: Houda Yasmine Ali Moussa (16855182)
منشور في: (2022)

Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 Cohort
حسب: Muneerah Smith (12542939)
منشور في: (2021)

Detecting protein complexes in protein interaction networks using Mapper and Graph Convolution Networks
حسب: Daou, Leonardo
منشور في: (2024)

Author Correction: Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation
حسب: Mona Elsafadi (18614905)
منشور في: (2019)

Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation
حسب: Mona Elsafadi (18614905)
منشور في: (2019)

Structural interactions of complex proteins with trehalose: mechanisms for improving the multilevel structure and functional properties of lentil-quinoa protein complexes
حسب: Mohammad Alrosan (20089263)
منشور في: (2024)

Insights Into the Role of CircRNAs: Biogenesis, Characterization, Functional, and Clinical Impact in Human Malignancies
حسب: Sabah Nisar (12561961)
منشور في: (2021)

20-HETE and EETs in Diabetic Nephropathy: A Novel Mechanistic Pathway
حسب: Stephanie Eid (440990)
منشور في: (2013)

Molecular docking, synthesis and biological evaluation of Vascular Endothelial Growth Factor (VEGF) B based peptide as antiangiogenic agent targeting the second domain of the Vascular Endothelial Growth Factor Receptor 1 (VEGFR1D2) for anticancer application
حسب: Afsaneh Sadremomtaz (11210280)
منشور في: (2020)

Proteomic analysis of <i>T. qataranse</i> exposed to lead (Pb) stress reveal new proteins with potential roles in Pb tolerance and detoxification mechanism
حسب: Kamal Usman (11482990)
منشور في: (2022)

Virome-wide serological profiling reveals association of herpesviruses with obesity
حسب: Mohammad Rubayet Hasan (8602080)
منشور في: (2021)

Reversal of Insulin Resistance in Overweight and Obese Subjects by trans-Resveratrol and Hesperetin Combination—Link to Dysglycemia, Blood Pressure, Dyslipidemia, and Low-Grade Inflammation
حسب: Naila Rabbani (291722)
منشور في: (2021)

Evaluation of cell disruption methods for protein and coenzyme Q10 quantification in purple non-sulfur bacteria
حسب: Ojima Z. Wada (14155734)
منشور في: (2024)

Concurrent targeting of BMI1 and CDK4/6 abrogates tumor growth in vitro and in vivo
حسب: Ramesh Elango (7542068)
منشور في: (2019)

Adipocyte Enhancer-Binding Protein 1 (AEBP1) (a Novel Macrophage Proinflammatory Mediator) Overexpression Promotes and Ablation Attenuates Atherosclerosis in ApoE⁻′⁻ and LDLR⁻′⁻ Mice
حسب: Bogachev, Oleg
منشور في: (2011)

The Yeast Permease Agp2 Senses Cycloheximide and Undergoes Degradation That Requires the Small Protein Brp1-Cellular Fate of Agp2 in Response to Cycloheximide
حسب: Ashima Mohanty (18599183)
منشور في: (2023)

Prediction and mechanistic analysis of drug-induced liver injury (DILI) based on chemical structure
حسب: Anika Liu (8411805)
منشور في: (2021)

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
حسب: Jinit, Masania
منشور في: (2023)

Caloric restriction reduces trabecular bone loss during aging and improves bone marrow adipocyte endocrine function in male mice
حسب: Charlotte Rinne (18766966)
منشور في: (2024)

Modification and Glycation Microalgae Proteins by Non-Thermal Assisted Process
حسب: Tahra El Obeid (20487143)
منشور في: (2024)

Salivary α-amylase activity is associated with cardiometabolic and inflammatory biomarkers in overweight/obese, non-diabetic Qatari women
حسب: Neyla S. Al Akl (15189997)
منشور في: (2024)

STAT1‐ and NFAT‐independent amplification of purinoceptor function integrates cellular senescence with interleukin‐6 production in preadipocytes
حسب: Yasser Majeed (9417974)
منشور في: (2022)

Enhancing the quality of lentil proteins via combination with whey proteins based on a dual process: a novel strategy through the incorporation of complexation and fermentation
حسب: Mohammad Alrosan (20089263)
منشور في: (2024)

An Intein-based Strategy for the Production of Tag-free Huntingtin Exon 1 Proteins Enables New Insights into the Polyglutamine Dependence of Httex1 Aggregation and Fibril Formation
حسب: Sophie Vieweg (7165526)
منشور في: (2016)