The outcomes of total hip arthroplasty in developmental dysplasia of hip versus osteoarthritis: a systematic review and meta-analysis

<h3>Purpose</h3><p dir="ltr">This systematic review and meta-analysis aimed to compare the outcomes of total hip arthroplasty (THA) in patients with developmental dysplasia of the hip (DDH) and those with osteoarthritis (OA).</p><h3>Methods</h3><p dir...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Loay A. Salman (14150322) (author)
مؤلفون آخرون: Osama Z. Alzobi (17346922) (author), Abdallah Al-Ani (10687939) (author), Ashraf T. Hantouly (14150319) (author), Mohammed Al-Juboori (15449046) (author), Ghalib Ahmed (14146800) (author)
منشور في: 2023
الموضوعات:
الوسوم: إضافة وسم
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author Loay A. Salman (14150322)
author2 Osama Z. Alzobi (17346922)
Abdallah Al-Ani (10687939)
Ashraf T. Hantouly (14150319)
Mohammed Al-Juboori (15449046)
Ghalib Ahmed (14146800)
author2_role author
author
author
author
author
author_facet Loay A. Salman (14150322)
Osama Z. Alzobi (17346922)
Abdallah Al-Ani (10687939)
Ashraf T. Hantouly (14150319)
Mohammed Al-Juboori (15449046)
Ghalib Ahmed (14146800)
author_role author
dc.creator.none.fl_str_mv Loay A. Salman (14150322)
Osama Z. Alzobi (17346922)
Abdallah Al-Ani (10687939)
Ashraf T. Hantouly (14150319)
Mohammed Al-Juboori (15449046)
Ghalib Ahmed (14146800)
dc.date.none.fl_str_mv 2023-07-06T03:00:00Z
dc.identifier.none.fl_str_mv 10.1007/s00590-023-03635-6
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/The_outcomes_of_total_hip_arthroplasty_in_developmental_dysplasia_of_hip_versus_osteoarthritis_a_systematic_review_and_meta-analysis/24980835
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Clinical sciences
Mathematical sciences
Statistics
Developmental dysplasia of the hip
Osteoarthritis
Total hip arthroplasty
Revision
Outcome
dc.title.none.fl_str_mv The outcomes of total hip arthroplasty in developmental dysplasia of hip versus osteoarthritis: a systematic review and meta-analysis
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3>Purpose</h3><p dir="ltr">This systematic review and meta-analysis aimed to compare the outcomes of total hip arthroplasty (THA) in patients with developmental dysplasia of the hip (DDH) and those with osteoarthritis (OA).</p><h3>Methods</h3><p dir="ltr">Four databases were searched from inception till February 2023 for original studies that compared the outcomes of THA in DDH and OA. The primary outcome was the revision rate; the secondary outcomes were dislocation and failure modes (i.e. aseptic loosening, PJI, instability, and periprosthetic fractures), hospital stay and costs. This review was conducted as per PRISMA guidelines, and the risk of bias was assessed using the Newcastle–Ottawa scale.</p><h3>Results</h3><p dir="ltr">A total of 9 observational studies with 575,255 THA (469,224 hips) were included, with a mean age of 50.6 years and 62.1 years for DDH and OA groups, respectively. There was a statistically significant difference in revision rate between DDH and OA patients in favour of OA (OR, 1.66; 95% CI 1.11–2.48; p-value, 0.0251). However, dislocation rate (OR, 1.78, 95% CI 0.58–5.51; p-value, 0.200), aseptic loosening (OR, 1.69; 95% CI 0.26–10.84; p-value, 0.346) and PJI (OR, 0.76; 95% CI 0.56–1.03; p-value, 0.063) were comparable across both groups.</p><h3>Conclusion</h3><p dir="ltr">A higher revision rate following total hip arthroplasty was associated with DDH compared with osteoarthritis. However, both groups had similar dislocation rates, aseptic loosening and PJI. Consideration of confounding factors, such as patient age and activity level, is crucial when interpreting these findings.</p><h3>Level of evidence</h3><p dir="ltr">III.</p><h3>Trial registration</h3><p dir="ltr">PROSPERO registration: CRD42023396192.</p><h2>Other Information</h2><p dir="ltr">Published in: European Journal of Orthopaedic Surgery & Traumatology<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s00590-023-03635-6" target="_blank">https://dx.doi.org/10.1007/s00590-023-03635-6</a></p><p dir="ltr">Additional institutions affiliated with: Surgical Specialty Center - HMC</p>
eu_rights_str_mv openAccess
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identifier_str_mv 10.1007/s00590-023-03635-6
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oai_identifier_str oai:figshare.com:article/24980835
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spelling The outcomes of total hip arthroplasty in developmental dysplasia of hip versus osteoarthritis: a systematic review and meta-analysisLoay A. Salman (14150322)Osama Z. Alzobi (17346922)Abdallah Al-Ani (10687939)Ashraf T. Hantouly (14150319)Mohammed Al-Juboori (15449046)Ghalib Ahmed (14146800)Biomedical and clinical sciencesClinical sciencesMathematical sciencesStatisticsDevelopmental dysplasia of the hipOsteoarthritisTotal hip arthroplastyRevisionOutcome<h3>Purpose</h3><p dir="ltr">This systematic review and meta-analysis aimed to compare the outcomes of total hip arthroplasty (THA) in patients with developmental dysplasia of the hip (DDH) and those with osteoarthritis (OA).</p><h3>Methods</h3><p dir="ltr">Four databases were searched from inception till February 2023 for original studies that compared the outcomes of THA in DDH and OA. The primary outcome was the revision rate; the secondary outcomes were dislocation and failure modes (i.e. aseptic loosening, PJI, instability, and periprosthetic fractures), hospital stay and costs. This review was conducted as per PRISMA guidelines, and the risk of bias was assessed using the Newcastle–Ottawa scale.</p><h3>Results</h3><p dir="ltr">A total of 9 observational studies with 575,255 THA (469,224 hips) were included, with a mean age of 50.6 years and 62.1 years for DDH and OA groups, respectively. There was a statistically significant difference in revision rate between DDH and OA patients in favour of OA (OR, 1.66; 95% CI 1.11–2.48; p-value, 0.0251). However, dislocation rate (OR, 1.78, 95% CI 0.58–5.51; p-value, 0.200), aseptic loosening (OR, 1.69; 95% CI 0.26–10.84; p-value, 0.346) and PJI (OR, 0.76; 95% CI 0.56–1.03; p-value, 0.063) were comparable across both groups.</p><h3>Conclusion</h3><p dir="ltr">A higher revision rate following total hip arthroplasty was associated with DDH compared with osteoarthritis. However, both groups had similar dislocation rates, aseptic loosening and PJI. Consideration of confounding factors, such as patient age and activity level, is crucial when interpreting these findings.</p><h3>Level of evidence</h3><p dir="ltr">III.</p><h3>Trial registration</h3><p dir="ltr">PROSPERO registration: CRD42023396192.</p><h2>Other Information</h2><p dir="ltr">Published in: European Journal of Orthopaedic Surgery & Traumatology<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s00590-023-03635-6" target="_blank">https://dx.doi.org/10.1007/s00590-023-03635-6</a></p><p dir="ltr">Additional institutions affiliated with: Surgical Specialty Center - HMC</p>2023-07-06T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s00590-023-03635-6https://figshare.com/articles/journal_contribution/The_outcomes_of_total_hip_arthroplasty_in_developmental_dysplasia_of_hip_versus_osteoarthritis_a_systematic_review_and_meta-analysis/24980835CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/249808352023-07-06T03:00:00Z
spellingShingle The outcomes of total hip arthroplasty in developmental dysplasia of hip versus osteoarthritis: a systematic review and meta-analysis
Loay A. Salman (14150322)
Biomedical and clinical sciences
Clinical sciences
Mathematical sciences
Statistics
Developmental dysplasia of the hip
Osteoarthritis
Total hip arthroplasty
Revision
Outcome
status_str publishedVersion
title The outcomes of total hip arthroplasty in developmental dysplasia of hip versus osteoarthritis: a systematic review and meta-analysis
title_full The outcomes of total hip arthroplasty in developmental dysplasia of hip versus osteoarthritis: a systematic review and meta-analysis
title_fullStr The outcomes of total hip arthroplasty in developmental dysplasia of hip versus osteoarthritis: a systematic review and meta-analysis
title_full_unstemmed The outcomes of total hip arthroplasty in developmental dysplasia of hip versus osteoarthritis: a systematic review and meta-analysis
title_short The outcomes of total hip arthroplasty in developmental dysplasia of hip versus osteoarthritis: a systematic review and meta-analysis
title_sort The outcomes of total hip arthroplasty in developmental dysplasia of hip versus osteoarthritis: a systematic review and meta-analysis
topic Biomedical and clinical sciences
Clinical sciences
Mathematical sciences
Statistics
Developmental dysplasia of the hip
Osteoarthritis
Total hip arthroplasty
Revision
Outcome