iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes

iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes

<p><strong>Poster by Noura Aldous, Ahmed Elsayed, Nehad Alajez, and Essam M. Abdelalim (Hamad Bin Khalifa University)</strong></p> <p>Background: Generation of pancreatic beta cells from human pluripotent stem cells (hPSCs) is a promising approach for studying diabetes...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Noura Aldous (15429873) (author)
مؤلفون آخرون:	Ahmed Elsayed (10311269) (author), Nehad Alajez (3563309) (author), Essam M. Abdelalim (14152596) (author)
منشور في:	2023
الموضوعات:	Biomedical and clinical sciences Medical biotechnology Pancreatic Development Endocrine Pancreas Transcription Factors β-cells miRNA-seq RNA-Seq
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة

iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes
حسب: Noura Aldous (15429873)
منشور في: (2023)

Identifying miRNA Signatures Associated with Pancreatic Islet Dysfunction in a FOXA2-Deficient iPSC Model
حسب: Ahmed K. Elsayed (13275302)
منشور في: (2024)

Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
حسب: Noura Aldous (15429873)
منشور في: (2024)

Genome-wide differential expression profiling of long non-coding RNAs in FOXA2 knockout iPSC-derived pancreatic cells
حسب: Ahmed K. Elsayed (13275302)
منشور في: (2023)

OutSingle: a novel method of detecting and injecting outliers in RNA-Seq count data using the optimal hard threshold for singular values
حسب: Edin Salkovic (16891479)
منشور في: (2023)

Single-cell transcriptomics identifies master regulators of neurodegeneration in SOD1 ALS iPSC-derived motor neurons
حسب: Seema C. Namboori (11031624)
منشور في: (2021)

RFX3 is essential for the generation of functional human pancreatic islets from stem cells
حسب: Bushra Memon (4792767)
منشور في: (2025)

Integrated Transcriptome and Pathway Analyses Revealed Multiple Activated Pathways in Breast Cancer
حسب: Radhakrishnan Vishnubalaji (3563306)
منشور في: (2019)

Identification of Novel Circulating miRNAs in Patients with Acute Ischemic Stroke
حسب: Eman K. Aldous (13914057)
منشور في: (2022)

Differentiation of human pluripotent stem cells into two distinct NKX6.1 populations of pancreatic progenitors
حسب: Idil I. Aigha (14913774)
منشور في: (2018)

Development and application of an integrated allele-specific pipeline for methylomic and epigenomic analysis (MEA)
حسب: Julien Richard Albert (655437)
منشور في: (2018)

Technical assessment of different extraction methods and transcriptome profiling of RNA isolated from small volumes of blood
حسب: Mahesh Kumar Reddy Kalikiri (17886695)
منشور في: (2023)

Immunoprofile of childhood diabetes
حسب: Meritxell Espino-Guarch (15430868)
منشور في: (2023)

A Generative AI Chatbot in High School Advising: A Qualitative Analysis of Domain-Specific Chatbot a ChatGPT
حسب: Khalil Assayed, Suha
منشور في: (2023)

Deep Learning Speech-Text Chatbot for High School Advising
حسب: Assayed, Suha Khalil
منشور في: (2024)

miRCOVID-19: Potential Targets of Human miRNAs in SARS-CoV-2 for RNA-Based Drug Discovery
حسب: Tanvir Alam (638619)
منشور في: (2021)

Circulating miRNAs, Small but Promising Biomarkers for Autism Spectrum Disorder
حسب: Salam Salloum-Asfar (656363)
منشور في: (2019)

OutPyR: Bayesian inference for RNA-Seq outlier detection
حسب: Edin Salkovic (16891479)
منشور في: (2020)

Genome-wide differential expression profiling of long non-coding RNAs (lncRNAs) in pancreatic cells derived from FOXA2-/- iPSCs
حسب: Ahmed K. Elsayed (13275302)
منشور في: (2023)

Scalable Generation of Mesenchymal Stem Cells and Adipocytes from Human Pluripotent Stem Cells
حسب: Manale Karam (3619412)
منشور في: (2020)

Correction to: Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1
حسب: Bushra Memon (4792767)
منشور في: (2018)

Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1
حسب: Bushra Memon (4792767)
منشور في: (2018)

Flavin Adenine Dinucleotide (FAD) and Pyridoxal 5′-Phosphate (PLP) Bind to Sox9 and Alter the Expression of Key Pancreatic Progenitor Transcription Factors
حسب: Zeyaul Islam (5867387)
منشور في: (2022)

Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model
حسب: Sahar Isa Da’as (18288880)
منشور في: (2022)

miRNA-dependent regulation of STIM1 expression in breast cancer
حسب: Rashmi P. Kulkarni (18618634)
منشور في: (2019)

Stem Cell Therapy for Diabetes: Beta Cells versus Pancreatic Progenitors
حسب: Bushra Memon (4792767)
منشور في: (2020)

NKX6.1 transcription factor: a crucial regulator of pancreatic β cell development, identity, and proliferation
حسب: Idil I. Aigha (14913774)
منشور في: (2020)

β-cell mitochondria in diabetes mellitus: a missing puzzle piece in the generation of hPSC-derived pancreatic β-cells?
حسب: Abdoulaye Diane (14152749)
منشور في: (2022)

Aberrant miRNA expression and protein arginine methyltransferase 5 (PRMT5) in cancer: A review
حسب: Saïd Sif (13616740)
منشور في: (2025)

Preclinical Evaluation of Human Pluripotent Stem Cells-Derived Pancreatic Progenitor Cells (hPSCs-PPs) Using Transgenic Zebrafish Models
حسب: Zahra Morshed (15430067)
منشور في: (2023)

Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
حسب: Khalil, Nathalie
منشور في: (2017)

Reciprocal interplays between MicroRNAs and pluripotency transcription factors in dictating stemness features in human cancers
حسب: Radhakrishnan Vishnubalaji (3563306)
منشور في: (2022)

Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas
حسب: Abu Saleh Md Moin (6189512)
منشور في: (2019)

Integrated whole transcriptome and small RNA analysis revealed multiple regulatory networks in colorectal cancer
حسب: Hibah Shaath (5599658)
منشور في: (2021)

Aberrant development of pancreatic beta cells derived from human iPSCs with FOXA2 deficiency
حسب: Ahmed K. Elsayed (13275302)
منشور في: (2022)

In vitro modeling of GCK mutation-associated monogenic diabetes using human iPSC and gene-editing technologies
حسب: Yasmin Abu Aqel (15430057)
منشور في: (2023)

Insights Into the Role of CircRNAs: Biogenesis, Characterization, Functional, and Clinical Impact in Human Malignancies
حسب: Sabah Nisar (12561961)
منشور في: (2021)

Trouble in Tiger country: isolated traumatic pancreatic transection – a case report
حسب: Ahmed Faidh Ramzee (17945120)
منشور في: (2023)

Epigenetic memory as crucial contributing factor in directing the differentiation of human iPSC into pancreatic β-cells in vitro
حسب: Abdoulaye Diane (14152749)
منشور في: (2025)

LNCRI: Long Non-Coding RNA Identifier in Multiple Species
حسب: Saleh Musleh (15279190)
منشور في: (2021)