Selective ROCK Inhibitor Enhances Blood Flow Recovery after Hindlimb Ischemia

Selective ROCK Inhibitor Enhances Blood Flow Recovery after Hindlimb Ischemia

<p dir="ltr">The impairment in microvascular network formation could delay the restoration of blood flow after acute limb ischemia. A high-content screen of a GSK-published kinase inhibitor library identified a set of ROCK inhibitor hits enhancing endothelial network formation. Subse...

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Bibliographic Details
Main Author: Hend Salah Fayed (17732622) (author)
Other Authors: Mouayad Zuheir Bakleh (19450432) (author), Jasni Viralippurath Ashraf (18518943) (author), Alison Howarth (7356479) (author), Daniel Ebner (5556488) (author), Ayman Al Haj Zen (16614801) (author)
Published: 2023
Subjects:
Biological sciences
Biochemistry and cell biology
Biomedical and clinical sciences
Pharmacology and pharmaceutical sciences
high content screening
kinase inhibitors
ROCK inhibitor
blood flow
limb ischemia
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