Maternal microbiota and gestational diabetes: impact on infant health
<div><p>Gestational diabetes mellitus (GDM) is a common complication of pregnancy that has been associated with an increased risk of obesity and diabetes in the offspring. Pregnancy is accompanied by tightly regulated changes in the endocrine, metabolic, immune, and microbial systems, an...
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| مؤلفون آخرون: | , , , |
| منشور في: |
2023
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إضافة وسم
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| _version_ | 1864513526560718848 |
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| author | Parul Singh (191877) |
| author2 | Duaa Ahmed Idris Elhaj (18002446) Ibrahim Ibrahim (673877) Hala Abdullahi (11304082) Souhaila Al Khodor (89983) |
| author2_role | author author author author |
| author_facet | Parul Singh (191877) Duaa Ahmed Idris Elhaj (18002446) Ibrahim Ibrahim (673877) Hala Abdullahi (11304082) Souhaila Al Khodor (89983) |
| author_role | author |
| dc.creator.none.fl_str_mv | Parul Singh (191877) Duaa Ahmed Idris Elhaj (18002446) Ibrahim Ibrahim (673877) Hala Abdullahi (11304082) Souhaila Al Khodor (89983) |
| dc.date.none.fl_str_mv | 2023-06-06T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1186/s12967-023-04230-3 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Maternal_microbiota_and_gestational_diabetes_impact_on_infant_health/25257160 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biological sciences Biochemistry and cell biology Microbiome GDM Neonatal health 16S rRNA |
| dc.title.none.fl_str_mv | Maternal microbiota and gestational diabetes: impact on infant health |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <div><p>Gestational diabetes mellitus (GDM) is a common complication of pregnancy that has been associated with an increased risk of obesity and diabetes in the offspring. Pregnancy is accompanied by tightly regulated changes in the endocrine, metabolic, immune, and microbial systems, and deviations from these changes can alter the mother’s metabolism resulting in adverse pregnancy outcomes and a negative impact on the health of her infant. Maternal microbiomes are significant drivers of mother and child health outcomes, and many microbial metabolites are likely to influence the host health. This review discusses the current understanding of how the microbiota and microbial metabolites may contribute to the development of GDM and how GDM-associated changes in the maternal microbiome can affect infant’s health. We also describe microbiota-based interventions that aim to improve metabolic health and outline future directions for precision medicine research in this emerging field.</p><p> </p></div><h2>Other Information</h2> <p> Published in: Journal of Translational Medicine<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1186/s12967-023-04230-3" target="_blank">https://dx.doi.org/10.1186/s12967-023-04230-3</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_fc1869af51c0aad3cf2964da423eff7d |
| identifier_str_mv | 10.1186/s12967-023-04230-3 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/25257160 |
| publishDate | 2023 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Maternal microbiota and gestational diabetes: impact on infant healthParul Singh (191877)Duaa Ahmed Idris Elhaj (18002446)Ibrahim Ibrahim (673877)Hala Abdullahi (11304082)Souhaila Al Khodor (89983)Biological sciencesBiochemistry and cell biologyMicrobiomeGDMNeonatal health16S rRNA<div><p>Gestational diabetes mellitus (GDM) is a common complication of pregnancy that has been associated with an increased risk of obesity and diabetes in the offspring. Pregnancy is accompanied by tightly regulated changes in the endocrine, metabolic, immune, and microbial systems, and deviations from these changes can alter the mother’s metabolism resulting in adverse pregnancy outcomes and a negative impact on the health of her infant. Maternal microbiomes are significant drivers of mother and child health outcomes, and many microbial metabolites are likely to influence the host health. This review discusses the current understanding of how the microbiota and microbial metabolites may contribute to the development of GDM and how GDM-associated changes in the maternal microbiome can affect infant’s health. We also describe microbiota-based interventions that aim to improve metabolic health and outline future directions for precision medicine research in this emerging field.</p><p> </p></div><h2>Other Information</h2> <p> Published in: Journal of Translational Medicine<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1186/s12967-023-04230-3" target="_blank">https://dx.doi.org/10.1186/s12967-023-04230-3</a></p>2023-06-06T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1186/s12967-023-04230-3https://figshare.com/articles/journal_contribution/Maternal_microbiota_and_gestational_diabetes_impact_on_infant_health/25257160CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/252571602023-06-06T03:00:00Z |
| spellingShingle | Maternal microbiota and gestational diabetes: impact on infant health Parul Singh (191877) Biological sciences Biochemistry and cell biology Microbiome GDM Neonatal health 16S rRNA |
| status_str | publishedVersion |
| title | Maternal microbiota and gestational diabetes: impact on infant health |
| title_full | Maternal microbiota and gestational diabetes: impact on infant health |
| title_fullStr | Maternal microbiota and gestational diabetes: impact on infant health |
| title_full_unstemmed | Maternal microbiota and gestational diabetes: impact on infant health |
| title_short | Maternal microbiota and gestational diabetes: impact on infant health |
| title_sort | Maternal microbiota and gestational diabetes: impact on infant health |
| topic | Biological sciences Biochemistry and cell biology Microbiome GDM Neonatal health 16S rRNA |