Blockade of TGF-β signaling to enhance the antitumor response is accompanied by dysregulation of the functional activity of CD4<sup>+</sup>CD25<sup>+</sup>Foxp3<sup>+</sup> and CD4<sup>+</sup>CD25<sup>−</sup>Foxp3<sup>+</sup> T cells
<h3>Background</h3><p dir="ltr">The pleiotropic cytokine, transforming growth factor (TGF)-β, and CD4<sup>+</sup>CD25<sup>+</sup>Foxp3<sup>+</sup> regulatory T cells (Tregs) play a critical role in actively suppressing antitumor immune...
محفوظ في:
| المؤلف الرئيسي: | Magdalena J. Polanczyk (14153283) (author) |
|---|---|
| مؤلفون آخرون: | Edwin Walker (4705993) (author), Daniel Haley (14153286) (author), Bella S. Guerrouahen (14153289) (author), Emmanuel T. Akporiaye (8335038) (author) |
| منشور في: |
2019
|
| الموضوعات: | |
| الوسوم: |
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