Phloretin attenuates STAT-3 activity and overcomes sorafenib resistance targeting SHP-1–mediated inhibition of STAT3 and Akt/VEGFR2 pathway in hepatocellular carcinoma
<h2>Background</h2><p dir="ltr">Hepatocellular carcinoma (HCC) is the most common primary liver malignancy. Phloretin (PH) possesses anticancer, antitumor, and hepatoprotective effects, however, the effects and potential mechanisms of phloretin remain elusive.</p>&l...
محفوظ في:
| المؤلف الرئيسي: | Sarita Saraswati (7509626) (author) |
|---|---|
| مؤلفون آخرون: | Abdulqader Alhaider (7509629) (author), Abdelgalil Mohamed Abdelgadir (14153268) (author), Pooja Tanwer (7509635) (author), Hesham M. Korashy (1474849) (author) |
| منشور في: |
2019
|
| الموضوعات: | |
| الوسوم: |
إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
|
مواد مشابهة
-
Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling
حسب: Sabah Akhtar (5809925)
منشور في: (2019) -
STAT3 promotes IFNγ/TNFα‐induced muscle wasting in an NF‐κB‐dependent and IL‐6‐independent manner
حسب: Jennifer F Ma (18629359)
منشور في: (2017) -
Signal Transducer and Activator of Transcription 3 (STAT3) Suppresses STAT1/Interferon Signaling Pathway and Inflammation in Senescent Preadipocytes
حسب: Aisha Y. Madani (14152911)
منشور في: (2021) -
The cross-talk between miRNAs and JAK/STAT pathway in cutaneous T cell lymphoma: Emphasis on therapeutic opportunities
حسب: Kalyani Patil (2679424)
منشور في: (2024) -
Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway
حسب: Kirti.S. Prabhu (17191231)
منشور في: (2021)