Mechanical overloading through mouse treadmill running increases HMGB1 levels in tendon matrix.

Mechanical overloading through mouse treadmill running increases HMGB1 levels in tendon matrix.

<p>(<b>A</b>) Immunostaining for HMGB1 under various mechanical loading conditions. (<b>a</b>) Achilles tendon (AT) from cage control mouse shows minimal HMGB1 staining in tendon matrix. (<b>e</b>) 20x magnification of (<b>a</b>) clearly shows th...

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Bibliographic Details
Main Author: Guangyi Zhao (187499) (author)
Other Authors: Jianying Zhang (256508) (author), Daibang Nie (7439201) (author), Yiqin Zhou (753373) (author), Feng Li (30515) (author), Kentaro Onishi (7439204) (author), Timothy Billiar (5767349) (author), James H-C. Wang (7439207) (author)
Published: 2019
Subjects:
Biophysics
Microbiology
Cell Biology
Molecular Biology
Physiology
Immunology
Developmental Biology
Marine Biology
Hematology
Infectious Diseases
Plant Biology
Biological Sciences not elsewhere classified
prostaglandin E 2
MMP
mobility group box 1
PGE
matrix metalloproteinase -3
HMGB 1 release
overloading Mechanical overloading
GL
tendon extracellular matrix
response
tendinopathy
tendon cells
HMGB 1 mediates
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