Image 5_A comparative analysis of non-invasive respiratory support modalities in the treatment of acute hypercapnic respiratory failure: a network meta-analysis.tif
Aim<p>The purpose of this study is to compare different non-invasive respiratory support methods for the treatment of acute hypercapnic respiratory failure (AHRF).</p>Methods<p>The network meta-analysis was conducted based on studies from PubMed, Embase, the Cochrane Library, and W...
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| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | |
| منشور في: |
2025
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| الموضوعات: | |
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إضافة وسم
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| _version_ | 1852018675992756224 |
|---|---|
| author | Liyu Yan (6172715) |
| author2 | Guishen Wu (21675653) |
| author2_role | author |
| author_facet | Liyu Yan (6172715) Guishen Wu (21675653) |
| author_role | author |
| dc.creator.none.fl_str_mv | Liyu Yan (6172715) Guishen Wu (21675653) |
| dc.date.none.fl_str_mv | 2025-07-08T04:08:34Z |
| dc.identifier.none.fl_str_mv | 10.3389/fmed.2025.1594128.s006 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/Image_5_A_comparative_analysis_of_non-invasive_respiratory_support_modalities_in_the_treatment_of_acute_hypercapnic_respiratory_failure_a_network_meta-analysis_tif/29499155 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Foetal Development and Medicine acute hypercapnic respiratory failure non-invasive respiratory support high-flow nasal cannula non-invasive ventilation conventional oxygen treatment |
| dc.title.none.fl_str_mv | Image 5_A comparative analysis of non-invasive respiratory support modalities in the treatment of acute hypercapnic respiratory failure: a network meta-analysis.tif |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | Aim<p>The purpose of this study is to compare different non-invasive respiratory support methods for the treatment of acute hypercapnic respiratory failure (AHRF).</p>Methods<p>The network meta-analysis was conducted based on studies from PubMed, Embase, the Cochrane Library, and Web of Science, from their inception to September 10, 2024. The outcomes was treatment failure, all-cause mortality, intubation, dyspnea score, length of stay in hospital, respiratory rate, arterial carbon dioxide partial pressure (PaCO<sub>2</sub>), and complications. The results of both direct and indirect comparisons were quantitatively assessed using weighted mean differences or relative risks with their respective 95% confidence intervals, and graphically depicted in forest plots. Additionally, the rank probabilities were presented, demonstrating the likelihood of each non-invasive respiratory support method being the most effective across various measured outcomes.</p>Results<p>Nineteen studies (2,022 participants) were included. The results indicated that the probability of treatment failure with face mask non-invasive ventilation (NIV) was lower than that of high-flow nasal cannula (HFNC) (RR: 1.42, 95% CI: 1.06, 1.93) and conventional oxygen treatment (COT) (RR: 1.87, 95% CI: 1.16, 3.03). Face mask NIV demonstrated superior performance in dyspnea score and PaCO<sub>2</sub> compared to HFNC, helmet NIV, and COT. The length of stay in the hospital for face mask NIV was relatively longer compared to HFNC (WMD: −0.73, 95% CI: −1.35, −0.10) and COT (WMD: −1.09, 95% CI: −2.00, −0.18), and the probability of complications was higher than with HFNC. The rank probability suggested that COT had the lowest likelihood of intubation and all-cause mortality, while helmet NIV may have the best effect on improving respiratory rate.</p>Conclusion<p>Concerning treatment failure, dyspnea score, and PaCO<sub>2</sub> improvement in patients with AHRF, face mask NIV may outperform other methods. For selected patients with AHRF, face mask NIV might be considered for potential first-line method. This study provides a certain level of evidence-based support for the management and treatment of AHRF, but more research is still needed in the future to determine the optimal non-invasive respiratory support method for treating patients with AHRF. In clinic, the efficacy of face mask NIV for better outcomes in patients with AHRH still requires validation.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_00aec8d342c59a08e218991e12e4fb3e |
| identifier_str_mv | 10.3389/fmed.2025.1594128.s006 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/29499155 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Image 5_A comparative analysis of non-invasive respiratory support modalities in the treatment of acute hypercapnic respiratory failure: a network meta-analysis.tifLiyu Yan (6172715)Guishen Wu (21675653)Foetal Development and Medicineacute hypercapnic respiratory failurenon-invasive respiratory supporthigh-flow nasal cannulanon-invasive ventilationconventional oxygen treatmentAim<p>The purpose of this study is to compare different non-invasive respiratory support methods for the treatment of acute hypercapnic respiratory failure (AHRF).</p>Methods<p>The network meta-analysis was conducted based on studies from PubMed, Embase, the Cochrane Library, and Web of Science, from their inception to September 10, 2024. The outcomes was treatment failure, all-cause mortality, intubation, dyspnea score, length of stay in hospital, respiratory rate, arterial carbon dioxide partial pressure (PaCO<sub>2</sub>), and complications. The results of both direct and indirect comparisons were quantitatively assessed using weighted mean differences or relative risks with their respective 95% confidence intervals, and graphically depicted in forest plots. Additionally, the rank probabilities were presented, demonstrating the likelihood of each non-invasive respiratory support method being the most effective across various measured outcomes.</p>Results<p>Nineteen studies (2,022 participants) were included. The results indicated that the probability of treatment failure with face mask non-invasive ventilation (NIV) was lower than that of high-flow nasal cannula (HFNC) (RR: 1.42, 95% CI: 1.06, 1.93) and conventional oxygen treatment (COT) (RR: 1.87, 95% CI: 1.16, 3.03). Face mask NIV demonstrated superior performance in dyspnea score and PaCO<sub>2</sub> compared to HFNC, helmet NIV, and COT. The length of stay in the hospital for face mask NIV was relatively longer compared to HFNC (WMD: −0.73, 95% CI: −1.35, −0.10) and COT (WMD: −1.09, 95% CI: −2.00, −0.18), and the probability of complications was higher than with HFNC. The rank probability suggested that COT had the lowest likelihood of intubation and all-cause mortality, while helmet NIV may have the best effect on improving respiratory rate.</p>Conclusion<p>Concerning treatment failure, dyspnea score, and PaCO<sub>2</sub> improvement in patients with AHRF, face mask NIV may outperform other methods. For selected patients with AHRF, face mask NIV might be considered for potential first-line method. This study provides a certain level of evidence-based support for the management and treatment of AHRF, but more research is still needed in the future to determine the optimal non-invasive respiratory support method for treating patients with AHRF. In clinic, the efficacy of face mask NIV for better outcomes in patients with AHRH still requires validation.</p>2025-07-08T04:08:34ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.3389/fmed.2025.1594128.s006https://figshare.com/articles/figure/Image_5_A_comparative_analysis_of_non-invasive_respiratory_support_modalities_in_the_treatment_of_acute_hypercapnic_respiratory_failure_a_network_meta-analysis_tif/29499155CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/294991552025-07-08T04:08:34Z |
| spellingShingle | Image 5_A comparative analysis of non-invasive respiratory support modalities in the treatment of acute hypercapnic respiratory failure: a network meta-analysis.tif Liyu Yan (6172715) Foetal Development and Medicine acute hypercapnic respiratory failure non-invasive respiratory support high-flow nasal cannula non-invasive ventilation conventional oxygen treatment |
| status_str | publishedVersion |
| title | Image 5_A comparative analysis of non-invasive respiratory support modalities in the treatment of acute hypercapnic respiratory failure: a network meta-analysis.tif |
| title_full | Image 5_A comparative analysis of non-invasive respiratory support modalities in the treatment of acute hypercapnic respiratory failure: a network meta-analysis.tif |
| title_fullStr | Image 5_A comparative analysis of non-invasive respiratory support modalities in the treatment of acute hypercapnic respiratory failure: a network meta-analysis.tif |
| title_full_unstemmed | Image 5_A comparative analysis of non-invasive respiratory support modalities in the treatment of acute hypercapnic respiratory failure: a network meta-analysis.tif |
| title_short | Image 5_A comparative analysis of non-invasive respiratory support modalities in the treatment of acute hypercapnic respiratory failure: a network meta-analysis.tif |
| title_sort | Image 5_A comparative analysis of non-invasive respiratory support modalities in the treatment of acute hypercapnic respiratory failure: a network meta-analysis.tif |
| topic | Foetal Development and Medicine acute hypercapnic respiratory failure non-invasive respiratory support high-flow nasal cannula non-invasive ventilation conventional oxygen treatment |