Overall study design.

<div><p>Parkinson’s disease (PD) is an increasingly prevalent neurologic condition for which symptomatic, but not preventative, treatment is available. Drug repurposing is an innovate drug discovery method that uncovers existing therapeutics to treat or prevent conditions for which they...

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Bibliographic Details
Main Author:	Maria P. Gorenflo (21395538) (author)
Other Authors:	Zhenxiang Gao (15596885) (author), Pamela B. Davis (11588570) (author), David Kaelber (11238188) (author), Rong Xu (296325) (author)
Published:	2025
Subjects:	Medicine Cell Biology Neuroscience Pharmacology Biotechnology Cancer Science Policy Infectious Diseases Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified uncovers existing therapeutics select potential drugs retrospective cohort analysis parkinson &# 8217 observational findings suggest biochemical processes implicated artificial intelligence prediction significantly reduced hazard amphetamine targets many 98 ), 0 hazard ratio 93 ), strongest candidate previous work prevent conditions main diagnosis inverse relationship incurable diseases drug repurposing dopaminergic synapses deidentified patients currently indicated confidence interval clinical corroboration amphetamine use 79 ). 6 years
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Overall study design.

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