This figure is similar to Fig 3, except that we use arm-3 instead of arm-2.
<p>The overall replication for arm-3 within the interval <i>i</i> ∈ [175, 350] is estimated at <i>p</i> ≲ 10<sup>3</sup>. Note that the SNP-overlap between arm-1 and arm-3 is only ∼ 50%.</p>
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , |
| منشور في: |
2025
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| الموضوعات: | |
| الوسوم: |
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| _version_ | 1852023186420400128 |
|---|---|
| author | Caroline C. McGrouther (5216153) |
| author2 | Aaditya V. Rangan (14659986) Arianna Di Florio (20636356) Jeremy A. Elman (9602147) Nicholas J. Schork (176346) John Kelsoe (3437189) |
| author2_role | author author author author author |
| author_facet | Caroline C. McGrouther (5216153) Aaditya V. Rangan (14659986) Arianna Di Florio (20636356) Jeremy A. Elman (9602147) Nicholas J. Schork (176346) John Kelsoe (3437189) |
| author_role | author |
| dc.creator.none.fl_str_mv | Caroline C. McGrouther (5216153) Aaditya V. Rangan (14659986) Arianna Di Florio (20636356) Jeremy A. Elman (9602147) Nicholas J. Schork (176346) John Kelsoe (3437189) |
| dc.date.none.fl_str_mv | 2025-01-29T18:23:49Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.pone.0314288.g004 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/This_figure_is_similar_to_Fig_3_except_that_we_use_arm-3_instead_of_arm-2_/28304638 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Genetics Neuroscience Pharmacology Biotechnology Evolutionary Biology Marine Biology Mental Health Infectious Diseases Plant Biology Biological Sciences not elsewhere classified termed &# 8216 psychiatric genomics consortium leverage recent advances e ., biclusters corrected biclustering algorithm subgroup may represent subgroup &# 8217 pgc containing 5781 various bd studies bd subtype information improve risk prediction specific pattern highlighted homogeneous genetic subgroup relatively small subset genetically homogeneous subtype discovered without using bicluster &# 8217 specific genetic pattern correlated genetic risk 2524 bd cases genetic heterogeneity delineating disorder </ p specific pattern genetic subgroup bd cases genetic level genetic data pgc ). 9752 cases bipolar disorder xlink "> successfully identified subphenotypic data subjects define set aside remaining data related signal prs ), primary focus particularly notable one way informed polygenic gwas analyses fully understood first apply expression across eliminate noise driven subgroups challenging task broad phenotype |
| dc.title.none.fl_str_mv | This figure is similar to Fig 3, except that we use arm-3 instead of arm-2. |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <p>The overall replication for arm-3 within the interval <i>i</i> ∈ [175, 350] is estimated at <i>p</i> ≲ 10<sup>3</sup>. Note that the SNP-overlap between arm-1 and arm-3 is only ∼ 50%.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_05d71dfb72068cff5535b5652bd79cb0 |
| identifier_str_mv | 10.1371/journal.pone.0314288.g004 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/28304638 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | This figure is similar to Fig 3, except that we use arm-3 instead of arm-2.Caroline C. McGrouther (5216153)Aaditya V. Rangan (14659986)Arianna Di Florio (20636356)Jeremy A. Elman (9602147)Nicholas J. Schork (176346)John Kelsoe (3437189)GeneticsNeurosciencePharmacologyBiotechnologyEvolutionary BiologyMarine BiologyMental HealthInfectious DiseasesPlant BiologyBiological Sciences not elsewhere classifiedtermed &# 8216psychiatric genomics consortiumleverage recent advancese ., biclusterscorrected biclustering algorithmsubgroup may representsubgroup &# 8217pgc containing 5781various bd studiesbd subtype informationimprove risk predictionspecific pattern highlightedhomogeneous genetic subgrouprelatively small subsetgenetically homogeneous subtypediscovered without usingbicluster &# 8217specific genetic patterncorrelated genetic risk2524 bd casesgenetic heterogeneity delineatingdisorder </ pspecific patterngenetic subgroupbd casesgenetic levelgenetic datapgc ).9752 casesbipolar disorderxlink ">successfully identifiedsubphenotypic datasubjects defineset asideremaining datarelated signalprs ),primary focusparticularly notableone wayinformed polygenicgwas analysesfully understoodfirst applyexpression acrosseliminate noisedriven subgroupschallenging taskbroad phenotype<p>The overall replication for arm-3 within the interval <i>i</i> ∈ [175, 350] is estimated at <i>p</i> ≲ 10<sup>3</sup>. Note that the SNP-overlap between arm-1 and arm-3 is only ∼ 50%.</p>2025-01-29T18:23:49ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.pone.0314288.g004https://figshare.com/articles/figure/This_figure_is_similar_to_Fig_3_except_that_we_use_arm-3_instead_of_arm-2_/28304638CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/283046382025-01-29T18:23:49Z |
| spellingShingle | This figure is similar to Fig 3, except that we use arm-3 instead of arm-2. Caroline C. McGrouther (5216153) Genetics Neuroscience Pharmacology Biotechnology Evolutionary Biology Marine Biology Mental Health Infectious Diseases Plant Biology Biological Sciences not elsewhere classified termed &# 8216 psychiatric genomics consortium leverage recent advances e ., biclusters corrected biclustering algorithm subgroup may represent subgroup &# 8217 pgc containing 5781 various bd studies bd subtype information improve risk prediction specific pattern highlighted homogeneous genetic subgroup relatively small subset genetically homogeneous subtype discovered without using bicluster &# 8217 specific genetic pattern correlated genetic risk 2524 bd cases genetic heterogeneity delineating disorder </ p specific pattern genetic subgroup bd cases genetic level genetic data pgc ). 9752 cases bipolar disorder xlink "> successfully identified subphenotypic data subjects define set aside remaining data related signal prs ), primary focus particularly notable one way informed polygenic gwas analyses fully understood first apply expression across eliminate noise driven subgroups challenging task broad phenotype |
| status_str | publishedVersion |
| title | This figure is similar to Fig 3, except that we use arm-3 instead of arm-2. |
| title_full | This figure is similar to Fig 3, except that we use arm-3 instead of arm-2. |
| title_fullStr | This figure is similar to Fig 3, except that we use arm-3 instead of arm-2. |
| title_full_unstemmed | This figure is similar to Fig 3, except that we use arm-3 instead of arm-2. |
| title_short | This figure is similar to Fig 3, except that we use arm-3 instead of arm-2. |
| title_sort | This figure is similar to Fig 3, except that we use arm-3 instead of arm-2. |
| topic | Genetics Neuroscience Pharmacology Biotechnology Evolutionary Biology Marine Biology Mental Health Infectious Diseases Plant Biology Biological Sciences not elsewhere classified termed &# 8216 psychiatric genomics consortium leverage recent advances e ., biclusters corrected biclustering algorithm subgroup may represent subgroup &# 8217 pgc containing 5781 various bd studies bd subtype information improve risk prediction specific pattern highlighted homogeneous genetic subgroup relatively small subset genetically homogeneous subtype discovered without using bicluster &# 8217 specific genetic pattern correlated genetic risk 2524 bd cases genetic heterogeneity delineating disorder </ p specific pattern genetic subgroup bd cases genetic level genetic data pgc ). 9752 cases bipolar disorder xlink "> successfully identified subphenotypic data subjects define set aside remaining data related signal prs ), primary focus particularly notable one way informed polygenic gwas analyses fully understood first apply expression across eliminate noise driven subgroups challenging task broad phenotype |