Ligand Binding to the Membrane-Distal Domain of the Met Receptor Induces Dimerization at the Membrane-Proximal Domain

Ligand Binding to the Membrane-Distal Domain of the Met Receptor Induces Dimerization at the Membrane-Proximal Domain

Activation of cytokine and growth factor receptors by ligands triggers crucial cellular responses in various physiological processes. However, our understanding of their structural basis remains incomplete due to the limited information on the active ligand–receptor complex structure. Their structur...

Бүрэн тодорхойлолт

-д хадгалсан:

Номзүйн дэлгэрэнгүй
Үндсэн зохиолч:	Neval Yilmaz (1544557) (author)
Бусад зохиолчид:	Hiroki Tanino (22686882) (author), Shun Sakuraba (1368381) (author), Romain Amyot (9657017) (author), Holger Flechsig (213426) (author), Atsushi Matsumoto (593817) (author), Hidetoshi Kono (19475) (author), Leonardo Puppulin (11688279) (author), Mikihiro Shibata (2075461) (author), Hiroshi Aoyama (832169) (author), Tsuyoshi Inoue (559318) (author), Kunio Matsumoto (412408) (author), Katsuya Sakai (11688282) (author)
Хэвлэсэн:	2025
Нөхцлүүд:	Biophysics Biochemistry Cell Biology Molecular Biology Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified molecular dynamics simulations luciferase complementary assay hepatocyte growth factor growth factor receptors electron microscopy experiments chemically fixing prior also conducted split various physiological processes proximal domain activation proximal region sema domain ipt4 domain distal domain physiological hgf structural features resolution characterization protein level living cells limited information induced dimerization active complex
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!

Ижил төстэй зүйлс

Ligand Binding to the Membrane-Distal Domain of the Met Receptor Induces Dimerization at the Membrane-Proximal Domain
-н: Neval Yilmaz (1544557)
Хэвлэсэн: (2025)

Ligand Binding to the Membrane-Distal Domain of the Met Receptor Induces Dimerization at the Membrane-Proximal Domain
-н: Neval Yilmaz (1544557)
Хэвлэсэн: (2025)

Ligand Binding to the Membrane-Distal Domain of the Met Receptor Induces Dimerization at the Membrane-Proximal Domain
-н: Neval Yilmaz (1544557)
Хэвлэсэн: (2025)

Ligand Binding to the Membrane-Distal Domain of the Met Receptor Induces Dimerization at the Membrane-Proximal Domain
-н: Neval Yilmaz (1544557)
Хэвлэсэн: (2025)

YajC co-expression does not alter the membrane localization or abundance of LdrA-FLAG.
-н: Yuto Nakamura (1493086)
Хэвлэсэн: (2025)

YajC recognition of LdrA requires both transmembrane and cytoplasmic domains.
-н: Yuto Nakamura (1493086)
Хэвлэсэн: (2025)

Description of neuropsychological measures and cognitive domains assessed.
-н: Lisa Ohlhauser (22676519)
Хэвлэсэн: (2025)

YajC Specifically Neutralizes Ldr Family Toxins.
-н: Yuto Nakamura (1493086)
Хэвлэсэн: (2025)

Overexpression of YajC is sufficient to alleviate LdrA-induced toxicity.
-н: Yuto Nakamura (1493086)
Хэвлэсэн: (2025)

Genetic Screen Identifies YajC as an LdrA-Neutralizing Factor.
-н: Yuto Nakamura (1493086)
Хэвлэсэн: (2025)

LdrA expression causes transient growth arrest and the FLAG tag does not affect its toxicity.
-н: Yuto Nakamura (1493086)
Хэвлэсэн: (2025)

YajC has no effect on unrelated TA toxins.
-н: Yuto Nakamura (1493086)
Хэвлэсэн: (2025)

Full, uncropped Western blot images corresponding to Fig 4A.
-н: Yuto Nakamura (1493086)
Хэвлэсэн: (2025)

Inducible overexpression of YajC-HA.
-н: Yuto Nakamura (1493086)
Хэвлэсэн: (2025)

Controls for LdrA toxicity and recovery experiments.
-н: Yuto Nakamura (1493086)
Хэвлэсэн: (2025)

Supplementary file 1_Twice-exceptional students: a systematic review to outline the distinctive characteristics through a multidimensional lens.docx
-н: Ludovica Rizzo (22687391)
Хэвлэсэн: (2025)

TEM observations of the vesicular structures and cell wall-plasma membrane interface ultrastructure of <i>N. benthamiana</i> epidermal cells in p33-expressing and control cells.
-н: Vicken Aknadibossian (22676694)
Хэвлэсэн: (2025)

Health Epidemiology in the women’s Rugby (HER) World Cup 2025
-н: Izzy Moore (6690647)
Хэвлэсэн: (2025)

<b>Excessive Lipolysis and Inflammatory Response in Adipose Tissue Are Associated with Elevated Serum Growth Hormone in Dairy Cows with Clinical Ketosis</b>
-н: Xinxing Gao (22653201)
Хэвлэсэн: (2025)

The p33 deletion mutant GFP:p33ΔN30 is localized in cytoplasmic aggregates compared to the plasma membrane and vesicle localization of GFP:p33 when ectopically expressed in <i>N. benthamiana</i> epidermal cells.
-н: Vicken Aknadibossian (22676694)
Хэвлэсэн: (2025)

Validation of the intermediary proteins between β-catenin and SMAD4.
-н: Lin Xie (136792)
Хэвлэсэн: (2025)

Application of STUPPIT to identify novel intermediary proteins between SMAD4 and β-catenin, central hubs of BMP and Wnt pathway.
-н: Lin Xie (136792)
Хэвлэсэн: (2025)

Validating the intermediary protein labeling efficiency of STUPPIT by mass spectrometry analysis.
-н: Lin Xie (136792)
Хэвлэсэн: (2025)

Proximity labeling of the intermediary protein LATS1 between MOB1A and YAP1 by STUPPIT.
-н: Lin Xie (136792)
Хэвлэсэн: (2025)

Proximity labeling of the intermediary protein AMOT between β-actin and YAP1 by STUPPIT.
-н: Lin Xie (136792)
Хэвлэсэн: (2025)

Design of STUPPIT for labeling and capturing intermediary proteins between two non-interacting proteins.
-н: Lin Xie (136792)
Хэвлэсэн: (2025)

Validation of the interaction of RNF20 with β-catenin and SMAD4 using PUP-IT system.
-н: Lin Xie (136792)
Хэвлэсэн: (2025)

Immunofluorescence analysis of the indicated proteins expressed in HeLa cells.
-н: Lin Xie (136792)
Хэвлэсэн: (2025)

Analysis of TRIM33 interactions with β-catenin and SMAD proteins.
-н: Lin Xie (136792)
Хэвлэсэн: (2025)

Validation of the YAP1 and actin related plasmids expression in the approach II of STUPPIT.
-н: Lin Xie (136792)
Хэвлэсэн: (2025)

Proximity labeling of the intermediary protein α-catenin between actin and β-catenin by STUPPIT.
-н: Lin Xie (136792)
Хэвлэсэн: (2025)

Immunoblotting confirmation that β-actin-PafA-Myc ligates 3 × Flag-TbN-PupE substrate to HA-AMOT.
-н: Lin Xie (136792)
Хэвлэсэн: (2025)

Western blot of purified p33 protein transiently expressed in <i>N. benthamiana</i> displaying protein bands which correspond to the expected sizes of p33 monomers, dimers, and tetramers.
-н: Vicken Aknadibossian (22676694)
Хэвлэсэн: (2025)

BTB domain and CNC homolog 1 (BACH1) is stabilized by Polo-like kinase 1 (PLK1).
-н: Fengyi Mao (15073242)
Хэвлэсэн: (2025)

Data Sheet 1_Enhancing preoperative HER2 status classification of invasive breast cancers using machine learning models based on clinicopathological and MRI features: a multicenter study.docx
-н: Suhong Zhao (10057478)
Хэвлэсэн: (2025)

FGFs in CKD
-н: Guillermo Gervasini (9650945)
Хэвлэсэн: (2025)

Summary of the multi-level models to predict cognition on seven difference neuropsychological outcome measures over five years.
-н: Lisa Ohlhauser (22676519)
Хэвлэсэн: (2025)

Participant demographics and descriptive statistics.
-н: Lisa Ohlhauser (22676519)
Хэвлэсэн: (2025)

Multi-level model specification equations to predict neuropsychological outcome measures.
-н: Lisa Ohlhauser (22676519)
Хэвлэсэн: (2025)

Cognitive Assessment Scores over time.
-н: Lisa Ohlhauser (22676519)
Хэвлэсэн: (2025)

Cannot write session to /tmp/vufind_sessions/sess_4o6tf5cnrct65c7qn2sornpg39