Stepwise kinase activation of DDR1 and DDR2 (1 μM protein autophosphorylation assay).
<p><b>A.</b> Schematic diagrams showing the location of key JM4 and A-loop tyrosine residues in DDR1-K-WT and DDR2-K-WT constructs. Anti-pY JM4 #1 binds to pY569 in DDR1 and to pY521 in DDR2. Anti-pY JM4 #2 binds to pY586 in DDR1 and to pY538 in DDR2. Anti-pY A-loop antibody was ra...
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2025
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