<i>N. brasiliensis</i> infection is comparable between iLck<sup>cre</sup>IL-4Rα<sup>−/lox</sup> and Lck<sup>cre</sup>IL-4Rα<sup>−/lox</sup> mice.
<p>iLck<sup>cre</sup>IL-4Rα<sup>−/lox</sup>, Lck<sup>cre</sup>IL-4Rα<sup>−/lox</sup> and control mice were infected with 750 <i>N. brasiliensis</i> L3 larvae. Faeces were collected from day 5 to 10 post infection (PI) and egg producti...
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2025
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| Sažetak: | <p>iLck<sup>cre</sup>IL-4Rα<sup>−/lox</sup>, Lck<sup>cre</sup>IL-4Rα<sup>−/lox</sup> and control mice were infected with 750 <i>N. brasiliensis</i> L3 larvae. Faeces were collected from day 5 to 10 post infection (PI) and egg production was calculated using the modified McMaster technique (A). At days 7 and 10 PI the worm burden in the small intestine was assessed (B). Intestinal goblet cell hyperplasia was assessed by determining the total number of PAS-positive goblet cells per 5 villi in histological sections of the small intestine at day 7 and 10 PI (C). Total IgE production in the serum was measured by ELISA at day 7 and 10 PI (D). The data are representative of the results of two independent experiments with mean values+SEM and n = 4 or 5 mice per group. ND, not detected, ns = not significant. One-Way-ANOVA, *<i>P<.05</i>, **<i>P<.01</i>.</p> <p>(TIF)</p> |
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